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Author

Shinsuke Toba

Observed names: Toba, Shinsuke, 鳥羽, 晋輔, 鳥羽晋輔
ORCID: 0000-0001-6185-1587
Observed ORCID: 0000-0001-6185-1587
OpenAlex ID: A5011713489
Discovery of S-217622, a Noncovalent Oral SARS-CoV-2 3CL Protease Inhibitor Clinical Candidate for Treating COVID-19
2022 · Yuto Unoh, Shota Uehara, et al. · Journal of Medicinal Chemistry · 646
In Vitro Antibacterial Properties of Cefiderocol, a Novel Siderophore Cephalosporin, against Gram-Negative Bacteria
2017 · Akinobu Ito, Takafumi Sato, et al. · Antimicrobial Agents and Chemotherapy · 428
SARS-CoV-2 variants with mutations at the S1/S2 cleavage site are generated in vitro during propagation in TMPRSS2-deficient cells
2021 · Michihito Sasaki, Kentaro Uemura, et al. · PLoS Pathogens · 183
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In Vivo Pharmacodynamic Study of Cefiderocol, a Novel Parenteral Siderophore Cephalosporin, in Murine Thigh and Lung Infection Models
2019 · Rio Nakamura, Tsukasa Ito-Horiyama, et al. · Antimicrobial Agents and Chemotherapy · 119
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S-217622, a SARS-CoV-2 main protease inhibitor, decreases viral load and ameliorates COVID-19 severity in hamsters
2022 · Michihito Sasaki, Koshiro Tabata, et al. · Science Translational Medicine · 110
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Discovery of Chlorofluoroacetamide-Based Covalent Inhibitors for Severe Acute Respiratory Syndrome Coronavirus 2 3CL Protease
2022 · Yuya Hirose, Naoya Shindo, et al. · Journal of Medicinal Chemistry · 57
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SARS-CoV-2 Bearing a Mutation at the S1/S2 Cleavage Site Exhibits Attenuated Virulence and Confers Protective Immunity
2021 · Michihito Sasaki, Shinsuke Toba, et al. · mBio · 46
Inhibition of avian-origin influenza A(H7N9) virus by the novel cap-dependent endonuclease inhibitor baloxavir marboxil
2019 · Keiichi Taniguchi, Yoshinori Ando, et al. · Scientific Reports · 39
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MRC5 cells engineered to express ACE2 serve as a model system for the discovery of antivirals targeting SARS-CoV-2
2021 · Kentaro Uemura, Michihito Sasaki, et al. · Scientific Reports · 32
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Efficacy of ensitrelvir against SARS-CoV-2 in a delayed-treatment mouse model
2022 · Haruaki Nobori, Keita Fukao, et al. · Journal of Antimicrobial Chemotherapy · 31
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Identification of Compound-B, a novel anti-dengue virus agent targeting the non-structural protein 4A
2018 · Haruaki Nobori, Shinsuke Toba, et al. · Antiviral Research · 29
Identification of cap-dependent endonuclease inhibitors with broad-spectrum activity against bunyaviruses
2022 · Shinsuke Toba, Akihiko Sato, et al. · Proceedings of the National Academy of Sciences · 27
Air-liquid interphase culture confers SARS-CoV-2 susceptibility to A549 alveolar epithelial cells
2021 · Michihito Sasaki, Mai Kishimoto, et al. · Biochemical and Biophysical Research Communications · 26
Characterization of the In Vitro and In Vivo Efficacy of Baloxavir Marboxil against H5 Highly Pathogenic Avian Influenza Virus Infection
2022 · Keiichi Taniguchi, Yoshinori Ando, et al. · Viruses · 25
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2-thiouridine is a broad-spectrum antiviral nucleoside analogue against positive-strand RNA viruses
2023 · Kentaro Uemura, Haruaki Nobori, et al. · Proceedings of the National Academy of Sciences · 24
Comprehensive analysis of resistance-nodulation-cell division superfamily (RND) efflux pumps from Serratia marcescens, Db10
2019 · Shinsuke Toba, Yusuke Minato, et al. · Scientific Reports · 24
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Combination therapy with oral antiviral and anti-inflammatory drugs improves the efficacy of delayed treatment in a COVID-19 hamster model
2023 · Michihito Sasaki, Tatsuki Sugi, et al. · EBioMedicine · 20
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5-Hydroxymethyltubercidin exhibits potent antiviral activity against flaviviruses and coronaviruses, including SARS-CoV-2
2021 · Kentaro Uemura, Haruaki Nobori, et al. · iScience · 16
Identification of quinolone derivatives as effective anti-Dengue virus agents
2020 · Haruaki Nobori, Kentaro Uemura, et al. · Antiviral Research · 11
Viral uptake and pathophysiology of the lung endothelial cells in age‐associated severe SARS‐CoV ‐2 infection models
2023 · Takuya Tsumita, Ryo Takeda, et al. · Aging Cell · 10
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Structure-activity relationship studies of anti-bunyaviral cap-dependent endonuclease inhibitors
2023 · Yoshiyuki Taoda, Akihiko Sato, et al. · Bioorganic & Medicinal Chemistry Letters · 10
Immunogenicity and protective efficacy of a co-formulated two-in-one inactivated whole virus particle COVID-19/influenza vaccine
2024 · Chimuka Handabile, Marumi Ohno, et al. · Scientific Reports · 8
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Isolation and Characterization of Distinct Rotavirus A in Bat and Rodent Hosts
2023 · Mai Kishimoto, Masahiro Kajihara, et al. · Journal of Virology · 8
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Serological characterization of lineage II insect-specific flaviviruses compared with pathogenic mosquito-borne flaviviruses
2022 · Koshiro Tabata, Yukari Itakura, et al. · Biochemical and Biophysical Research Communications · 5
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Synergistic antiviral activity of a cathepsin B/L inhibitor and a TMPRSS2 inhibitor against SARS-CoV-2 in vitro and in vivo
2025 · Shinsuke Toba, Kentaro Uemura, et al. · Virology · 4
Works count: 40
Citation count: 1,931
H-index: 17
I10-index: 21
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