Author

Müge Didem Orhan

Observed names: Didem Müge Orhan, Muge D. Orhan, Muge Didem Orhan, Orhan, Muge Didem, Timuçin Avşar

Observed institution: Bahçeşehir University

ORCID: 0000-0001-9014-3838

Observed ORCID: 0000-0001-9014-3838

OpenAlex ID: A5011759979

Near-physiological-temperature serial crystallography reveals conformations of SARS-CoV-2 main protease active site for improved drug repurposing

2021 · Serdar Durdagi, Çağdaş Dağ, et al. · Structure · 45

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The neutralization effect of montelukast on SARS-CoV-2 is shown by multiscale in silico simulations and combined in vitro studies

2021 · Serdar Durdagi, Timucin Avsar, et al. · Molecular Therapy · 35

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Integrating Ligand and Target-Driven Based Virtual Screening Approaches With in vitro Human Cell Line Models and Time-Resolved Fluorescence Resonance Energy Transfer Assay to Identify Novel Hit Compounds Against BCL-2

2020 · Gurbet Tutumlu, Berna Dogan, et al. · Frontiers in Chemistry · 35

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Instant determination of the artemisinin from various Artemisia annua L. extracts by LC‐ESI‐MS/MS and their in‐silico modelling and in vitro antiviral activity studies against SARS‐CoV‐2

2021 · Kubra Dogan, Ebru Erol, et al. · Phytochemical Analysis · 23

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An Integrated in silico Approach and in vitro Study for the Discovery of Small‐Molecule USP7 Inhibitors as Potential Cancer Therapies

2020 · Duaa Kanan, Tarek Kanan, et al. · ChemMedChem · 22

Anti-SARS-CoV-2 and cytotoxic activity of two marine alkaloids from green alga Caulerpa cylindracea Sonder in the Dardanelles

2022 · Ebru Erol, Muge Didem Orhan, et al. · RSC Advances · 19

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Hybrid In Silico and TR-FRET-Guided Discovery of Novel BCL-2 Inhibitors

2021 · Kader Sahin, Muge Didem Orhan, et al. · ACS Pharmacology & Translational Science · 19

Screening of Clinically Approved and Investigation Drugs as Potential Inhibitors of SARS‐CoV‐2: A Combinedin silicoandin vitroStudy

2021 · Serdar Durdagi, Muge Didem Orhan, et al. · Molecular Informatics · 18

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Biochemical characterization and detection of antitumor activity of l-asparaginase from thermophilic Geobacillus kaustophilus DSM 7263T

2022 · F. İnci Özdemir, Müge Didem Orhan, et al. · Protein Expression and Purification · 17

Proposing novel MDM2 inhibitors: Combined physics‐driven high‐throughput virtual screening and in vitro studies

2020 · Gulsah Aydin, Maide Nur Paksoy, et al. · Chemical Biology & Drug Design · 11

Synthesis, Characterization, Biological Activity and Molecular Modeling Studies of Novel Aminoguanidine Derivatives

2022 · Nuriye Doğan, Sevtap Çağlar Yavuz, et al. · ChemistrySelect · 8

Niraparib Demonstrates Therapeutic Potential in Multiple Sclerosis through Inhibition of IL-17A Receptor Interaction and Promotion of Remyelination

2025 · Muge Didem Orhan, Lalehan Oktay, et al. · ACS Chemical Neuroscience · 2

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Targeting BCL-2 through Deep Learning-Based Drug Repurposing: A Multimodal Approach Combining Diffusion-Based Generative Modeling, Neural Relational Inference, and In Vitro Validation

2026 · Ehsan Sayyah, Hüseyin Tunç, et al. · Journal of Chemical Information and Modeling · 1

Spastin Is Required to Prevent SPAST ‐Related Demyelination

2026 · Şeyma Akarsu, Didem Müge Orhan, et al. · Journal of Neurochemistry

Author response for "Spastin is Required to Prevent SPAST-Related Demyelination"

2026 · Şeyma Akarsu, Didem Müge Orhan, et al. · Publons reviews and discussion

CCDC 1959614: Experimental Crystal Structure Determination

2023 · Doğan, Nuriye, Yavuz, Sevtap Çağlar, et al. · The Cambridge Structural Database

Works count: 16

Citation count: 255

H-index: 10

I10-index: 10