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Robert S. Mittler

Observed names: R Mittler, R S Mittler, R. S. Mittler, R.S. Mittler, ROBERT S. MITTLER, Robert Mittler, Robert S Mittler, Robert. S. Mittler
Observed institutions: La Jolla Institute for Immunology, Oregon State University, St. Jude Children's Research Hospital, National Agriculture and Food Research Organization, Memorial Sloan Kettering Cancer Center, Emory University, New York Medical College, University of Washington, University of Ulsan, NYU Langone Health, Bristol-Myers Squibb (United States), Dana-Farber Cancer Institute, Ulsan University Hospital, Atlanta VA Medical Center, Ortho Clinical Diagnostics (United States), Max Planck Institute of Immunobiology and Epigenetics, Benaroya Research Institute, Emory National Primate Research Center, Ortho-McNeil Pharmaceutical (United States), New York University, UConn Health, Columbia University
OpenAlex ID: A5011979031
Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors
1997 · Ignacio Melero, Walter W. Shuford, et al. · Nature Medicine · 898
4-1BB Costimulatory Signals Preferentially Induce CD8+ T Cell Proliferation and Lead to the Amplification In Vivo of Cytotoxic T Cell Responses
1997 · Walter W. Shuford, Kerry Klussman, et al. · The Journal of Experimental Medicine · 804
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Intracellular Trafficking of CTLA-4 and Focal Localization Towards Sites of TCR Engagement
1996 · Peter S Linsley, Jeff Bradshaw, et al. · Immunity · 609
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Cutting Edge: 4-1BB Is a Bona Fide CD8 T Cell Survival Signal
1999 · Chikara Takahashi, Robert S Mittler, et al. · The Journal of Immunology · 379
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NK1.1 Cells Express 4-1BB (CDw137) Costimulatory Molecule and Are Required for Tumor Immunity Elicited by Anti-4-1BB Monoclonal Antibodies
1998 · Ignacio Melero, Janet V. Johnston, et al. · Cellular Immunology · 363
Multivalent 4-1BB binding aptamers costimulate CD8+ T cells and inhibit tumor growth in mice
2008 · James O. McNamara, Despina Kolonias, et al. · Journal of Clinical Investigation · 310
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Eradication of established tumors in mice by a combination antibody-based therapy
2006 · Tomoyasu Uno, Kazuyoshi Takeda, et al. · Nature Medicine · 257
Cutting Edge: Expression of Functional CD137 Receptor by Dendritic Cells
2002 · Ryan A Wilcox, Andrei I Chapoval, et al. · The Journal of Immunology · 231
Amplification of tumor immunity by gene transfer of the co-stimulatory 4-1BB ligand: synergy with the CD28 co-stimulatory pathway
1998 · Ignacio Melero, Nathan Bach, et al. · European Journal of Immunology · 217
Patterns of antigenic expression on human monocytes as defined by monoclonal antibodies
1983 · M.A. Talle, P.E. Rao, et al. · Cellular Immunology · 207
CD137 costimulatory T cell receptor engagement reverses acute disease in lupus-prone NZB × NZW F1 mice
2003 · Juergen Foell, Simona Strahotin, et al. · Journal of Clinical Investigation · 176
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Anti–4-1bb Monoclonal Antibodies Abrogate T Cell–Dependent Humoral Immune Responses in Vivo through the Induction of Helper T Cell Anergy
1999 · Robert S. Mittler, Tina S. Bailey, et al. · The Journal of Experimental Medicine · 174
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Cytokine-Mediated Disruption of Lymphocyte Trafficking, Hemopoiesis, and Induction of Lymphopenia, Anemia, and Thrombocytopenia in Anti-CD137-Treated Mice
2007 · Liguo Niu, Simona Strahotin, et al. · The Journal of Immunology · 171
CD134 Plus CD137 Dual Costimulation Induces Eomesodermin in CD4 T Cells To Program Cytotoxic Th1 Differentiation
2011 · Harry Z Qui, Adam T Hagymasi, et al. · The Journal of Immunology · 158
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Correction: Corrigendum: Long-lived antigen-induced IgM plasma cells demonstrate somatic mutations and contribute to long-term protection
2016 · Caitlin Bohannon, Ryan Powers, et al. · Nature Communications · 149
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ZAP-70 tyrosine kinase, CD45, and T cell receptor involvement in UV- and H2O2-induced T cell signal transduction.
1994 · G.L. Schieven, R.S. Mittler, et al. · Journal of Biological Chemistry · 148
4-1BB Costimulation Is Required for Protective Anti-Viral Immunity After Peptide Vaccination
2000 · Joyce T Tan, Jason K Whitmire, et al. · The Journal of Immunology · 140
Cutting Edge: Deficiency in the E3 Ubiquitin Ligase Cbl-b Results in a Multifunctional Defect in T Cell TGF-β Sensitivity In Vitro and In Vivo
2006 · Elizabeth A Wohlfert, Leonid Gorelik, et al. · The Journal of Immunology · 137
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Immunity to Pre-1950 H1N1 Influenza Viruses Confers Cross-Protection against the Pandemic Swine-Origin 2009 A (H1N1) Influenza Virus
2010 · Ioanna Skountzou, Dimitrios G Koutsonanos, et al. · The Journal of Immunology · 134
Synergism Between HIV gp120 and gp120-Specific Antibody in Blocking Human T Cell Activation
1989 · Robert S. Mittler, Michael K. Hoffmann · Science · 131
Long-lived antigen-induced IgM plasma cells demonstrate somatic mutations and contribute to long-term protection
2016 · Caitlin Bohannon, Ryan Powers, et al. · Nature Communications · 119
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4-1BB and OX40 Dual Costimulation Synergistically Stimulate Primary Specific CD8 T Cells for Robust Effector Function
2004 · Seung-Joo Lee, Lara Myers, et al. · The Journal of Immunology · 118
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4-1BB co-stimulation enhances human CD8+ T cell priming by augmenting the proliferation and survival of effector CD8+ T cells
2002 · D. Laderach, M. Movassagh, et al. · International Immunology · 103
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T-cell receptor-CD4 physical association in a murine T-cell hybridoma: induction by antigen receptor ligation.
1989 · R S Mittler, S J Goldman, et al. · Proceedings of the National Academy of Sciences · 103
4-1BB Signaling Synergizes with Programmed Death Ligand 1 Blockade To Augment CD8 T Cell Responses during Chronic Viral Infection
2011 · Vaiva Vezys, Pablo Penaloza-MacMaster, et al. · The Journal of Immunology · 102
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Works count: 128
Citation count: 9,757
H-index: 56
I10-index: 95
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