Author

Kate M. Saville

Observed names: Kate M. Saville, Kate Saville

Institutions: USA Mitchell Cancer Institute, University of South Alabama

Observed institutions: USA Mitchell Cancer Institute, University of South Alabama

ORCID: 0000-0001-7011-9304

Observed ORCID: 0000-0001-7011-9304

OpenAlex ID: A5012187207

Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD+/SIRT6 axis

2021 · Christopher A. Koczor, Kate M. Saville, et al. · Cell Reports · 69

NAD+-mediated regulation of mammalian base excision repair

2020 · Kate M. Saville, Jennifer Clark, et al. · DNA repair · 45

NAD+ bioavailability mediates PARG inhibition-induced replication arrest, intra S-phase checkpoint and apoptosis in glioma stem cells

2021 · Jianfeng Li, Kate M. Saville, et al. · NAR Cancer · 34

Overcoming Temozolomide Resistance in Glioblastoma via Enhanced NAD+ Bioavailability and Inhibition of Poly-ADP-Ribose Glycohydrolase

2022 · Jianfeng Li, Christopher A. Koczor, et al. · Cancers · 19

Live Cell Detection of Poly(ADP-Ribose) for Use in Genetic and Genotoxic Compound Screens

2022 · Christopher A. Koczor, Aaron J. Haider, et al. · Cancers · 13

Overexpression of the WWE domain of RNF146 modulates poly-(ADP)-ribose dynamics at sites of DNA damage

2025 · Rasha Q. Al-Rahahleh, Wynand P. Roos, et al. · DNA repair · 9

Quantitative Analysis of Nuclear Poly(ADP-Ribose) Dynamics in Response to Laser-Induced DNA Damage

2022 · Christopher A. Koczor, Kate M. Saville, et al. · Methods in molecular biology · 9

Oncometabolite 2-hydroxyglutarate suppresses basal protein levels of DNA polymerase beta that enhances alkylating agent and PARG inhibition induced cytotoxicity

2024 · Kate M. Saville, Rasha Q. Al-Rahahleh, et al. · DNA repair · 7

Abstract 4972: Novel Ras inhibitor DC070-547 potently and selectively blocks Ras-RBD binding, EGFR binding to Ras signaling complex, EGFR activation of Ras signaling, and growth of Ras-driven lung tumor cells

2017 · Bing Zhu, Xi Chen, et al. · Cancer Research

Abstract 5166: Sensitivity of melanoma cells to a novel class of Ras inhibitors

2017 · Kate M. Saville, Kevin Lee, et al. · Cancer Research

Works count: 10

Citation count: 205

H-index: 7

I10-index: 5