Author

Philip V. Seegren

Observed names: Philip Seegren, Philip V Seegren, Seegren V. Philip

Institutions: Johns Hopkins University, Johns Hopkins Medicine

Observed institutions: James Madison University, Johns Hopkins University, Johns Hopkins Medicine, Advanced Bioscience Laboratories (United States), University of Virginia

ORCID: 0000-0002-7153-4670

Observed ORCID: 0000-0002-7153-4670

OpenAlex ID: A5012332452

Chanzyme TRPM7 Mediates the Ca2+ Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation

2018 · Michael S. Schappe, Kalina Szteyn, et al. · Immunity · 252

Expanding the Diversity of Mycobacteriophages: Insights into Genome Architecture and Evolution

2011 · Welkin H. Pope, Deborah Jacobs-Sera, et al. · PLoS ONE · 154

Macrophage acetyl-CoA carboxylase regulates acute inflammation through control of glucose and lipid metabolism

2022 · Scott Yeudall, Clint M. Upchurch, et al. · Science Advances · 91

Reduced mitochondrial calcium uptake in macrophages is a major driver of inflammaging

2023 · Philip V. Seegren, Logan R. Harper, et al. · Nature Aging · 88

Neuronal hyperexcitability is a DLK-dependent trigger of herpes simplex virus reactivation that can be induced by IL-1

2020 · Sean R Cuddy, Austin R Schinlever, et al. · eLife · 53

Efferocytosis requires periphagosomal Ca2+-signaling and TRPM7-mediated electrical activity

2022 · Michael S. Schappe, Marta E. Stremska, et al. · Nature Communications · 43

A Novel MVA-Based Multiphasic Vaccine for Prevention or Treatment of Tuberculosis Induces Broad and Multifunctional Cell-Mediated Immunity in Mice and Primates

2015 · Stéphane Leung-Theung-Long, Marie Gouanvic, et al. · PLoS ONE · 41

Mitochondrial Ca2+ Signaling Is an Electrometabolic Switch to Fuel Phagosome Killing

2020 · Philip V. Seegren, Taylor K. Downs, et al. · Cell Reports · 31

Analogs of FTY720 inhibit TRPM7 but not S1PRs and exert multimodal anti-inflammatory effects

2023 · Gregory W. Busey, Mohan C. Manjegowda, et al. · The Journal of General Physiology · 9

Novel TRPM7 inhibitors with potent anti-inflammatory effects in vivo

2023 · Gregory W. Busey, Mohan C. Manjegowda, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2

TRPM7 regulates phagocytosis and clearance of Candida albicans

2023 · Marta E. Stremska, Eric J. Stipes, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1

Defining a leptomeningeal blood–cerebrospinal fluid barrier as a specialized vascular interface

2026 · Philip V. Seegren · bioRxiv (Cold Spring Harbor Laboratory)

An Unexpected Role for Acetyl Coenzyme A Carboxylase in Metabolic Control of the Macrophage Acute Inflammatory Response

2022 · Scott Yeudall, Clint Upchurch, et al. · Free Radical Biology and Medicine

Author response: Neuronal hyperexcitability is a DLK-dependent trigger of herpes simplex virus reactivation that can be induced by IL-1

2020 · Sean R Cuddy, Austin R Schinlever, et al.

Works count: 14

Citation count: 765

H-index: 9

I10-index: 8