Author

Le Xie

Observed names: L Y Xie, L. Xie, Lixin Xie

Institutions: Nankai University, Chinese PLA General Hospital, Chinese General Hospital College of Nursing and Liberal Arts, Wuhan Union Hospital, Shandong First Medical University, Huazhong University of Science and Technology

Observed institutions: Ministry of Education of the People's Republic of China, Nankai University, Chinese PLA General Hospital, Chinese General Hospital College of Nursing and Liberal Arts, Foshan Hospital of TCM, Hunan Academy of Traditional Chinese Medicine, Wuhan Union Hospital, Chinese People's Liberation Army, Shandong First Medical University, Hunan Provincial Hospital of Integrated Traditional Chinese and Western Medicine (The Affiliated Hospital of Hunan Academy of Traditional Chinese Medicine), Huazhong University of Science and Technology

ORCID: 0000-0002-9931-328X

Observed ORCID: 0000-0002-9931-328X

OpenAlex ID: A5012374056

N-Acetylcysteine Combined With Dexamethasone Treatment Improves Sudden Sensorineural Hearing Loss and Attenuates Hair Cell Death Caused by ROS Stress

2021 · Xue Bai, Sen Chen, et al. · Frontiers in Cell and Developmental Biology · 46

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Capsaicin and dihydrocapsaicin induce apoptosis in human glioma cells via ROS and Ca2+-mediated mitochondrial pathway

2016 · Le Xie, Guang-Hong Xiang, et al. · Molecular Medicine Reports · 45

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Reduced Connexin26 in the Mature Cochlea Increases Susceptibility to Noise-Induced Hearing Loss in Mice

2016 · Xing-Xing Zhou, Sen Chen, et al. · International Journal of Molecular Sciences · 40

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Developmental abnormalities in supporting cell phalangeal processes and cytoskeleton in the Gjb2 knockdown mouse model

2018 · Sen Chen, Le Xie, et al. · Disease Models & Mechanisms · 36

Degradation of cochlear Connexin26 accelerate the development of age‐related hearing loss

2023 · Kai Xu, Sen Chen, et al. · Aging Cell · 33

The protective effects of systemic dexamethasone on sensory epithelial damage and hearing loss in targeted Cx26-null mice

2022 · Kai Xu, Sen Chen, et al. · Cell Death and Disease · 31

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The spatial distribution pattern of Connexin26 expression in supporting cells and its role in outer hair cell survival

2018 · Sen Chen, Kai Xu, et al. · Cell Death and Disease · 31

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Association between white matter alterations and domain-specific cognitive impairment in cerebral small vessel disease: A meta-analysis of diffusion tensor imaging

2022 · Yao Xie, Le Xie, et al. · Frontiers in Aging Neuroscience · 23

Local Macrophage-Related Immune Response Is Involved in Cochlear Epithelial Damage in Distinct Gjb2-Related Hereditary Deafness Models

2021 · Kai Xu, Sen Chen, et al. · Frontiers in Cell and Developmental Biology · 23

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Reduced postnatal expression of cochlear Connexin26 induces hearing loss and affects the developmental status of pillar cells in a dose-dependent manner

2019 · Le Xie, Sen Chen, et al. · Neurochemistry International · 20

Viral‐Mediated Connexin 26 Expression Combined with Dexamethasone Rescues Hearing in a Conditional Gjb2 Null Mice Model

2024 · Xiaohui Wang, Li Zhang, et al. · Advanced Science · 18

F-Actin Dysplasia Involved in Organ of Corti Deformity in Gjb2 Knockdown Mouse Model

2022 · Xiao-zhou Liu, Yuan Jin, et al. · Frontiers in Molecular Neuroscience · 15

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Hearing Screening Combined with Target Gene Panel Testing Increased Etiological Diagnostic Yield in Deaf Children

2021 · Le Xie, Yue Qiu, et al. · Neural Plasticity · 15

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Abnormal Innervation, Demyelination, and Degeneration of Spiral Ganglion Neurons as Well as Disruption of Heminodes are Involved in the Onset of Deafness in Cx26 Null Mice

2024 · Yue Qiu, Le Xie, et al. · Neuroscience Bulletin · 14

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Hollow Mesoporous Silica@Zeolitic Imidazolate Framework Capsules and Their Applications for Gentamicin Delivery

2018 · Xiaoxiang Xu, Heyin Chen, et al. · Neural Plasticity · 14

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Jervell and Lange-Nielsen Syndrome due to a Novel Compound Heterozygous KCNQ1 Mutation in a Chinese Family

2020 · Yue Qiu, Sen Chen, et al. · Neural Plasticity · 12

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Effects of extracellular vesicles for ischemic stroke: A meta‑analysis of preclinical studies

2024 · Yuan Xie, Tianhao Deng, et al. · Experimental and Therapeutic Medicine · 10

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PARP inhibitor rescues hearing and hair cell impairment in Cx26‐null mice

2023 · Xiaohui Wang, Sen Chen, et al. · Open Research (University of Surrey) · 10

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Auditory Neuropathy Spectrum Disorder due to Two Novel Compound Heterozygous OTOF Mutations in Two Chinese Families

2019 · Yue Qiu, Sen Chen, et al. · Neural Plasticity · 10

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A Supramolecular Material for Controlling Kiwifruit Bacterial Canker

2025 · Xile Deng, Qiang Bian, et al. · Advanced Science · 9

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The Dual Roles of Triiodothyronine in Regulating the Morphology of Hair Cells and Supporting Cells during Critical Periods of Mouse Cochlear Development

2023 · Xue Bai, Kai Xu, et al. · International Journal of Molecular Sciences · 9

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CCDC154 Mutant Caused Abnormal Remodeling of the Otic Capsule and Hearing Loss in Mice

2021 · Kai Xu, Xue Bai, et al. · Frontiers in Cell and Developmental Biology · 9

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Efficacy and safety of naotaifang capsules for hypertensive cerebral small vessel disease: Study protocol for a multicenter, randomized, double-blind, placebo-controlled clinical trial

2023 · Rui Fang, Hua Hu, et al. · Frontiers in Pharmacology · 7

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Targeted Next-Generation Sequencing Identified Novel Compound Heterozygous Variants in the PTPRQ Gene Causing Autosomal Recessive Hearing Loss in a Chinese Family

2022 · Yuan Jin, Xiao-Zhou Liu, et al. · Frontiers in Genetics · 7

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A Novel Spontaneous Mutation of the SOX10 Gene Associated with Waardenburg Syndrome Type II

2020 · Sen Chen, Yuan Jin, et al. · Neural Plasticity · 7

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Works count: 47

Citation count: 532

H-index: 14

I10-index: 19