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Claire B. Discenza

Observed names: CLAIRE B DISCENZA, Claire B Discenza, Claire Discenza
ORCID: 0009-0008-7794-1147
Observed ORCID: 0009-0008-7794-1147
OpenAlex ID: A5012431998
Targeting the transferrin receptor to transport antisense oligonucleotides across the mammalian blood-brain barrier
2024 · Scarlett J. Barker, Mai B. Thayer, et al. · Science Translational Medicine · 137
Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomes
2024 · Jing L. Guo, Dylan Braun, et al. · Cell · 91
Fc-engineered large molecules targeting blood-brain barrier transferrin receptor and CD98hc have distinct central nervous system and peripheral biodistribution
2025 · Nathalie Khoury, Michelle E. Pizzo, et al. · Nature Communications · 63
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Transferrin receptor–targeted anti-amyloid antibody enhances brain delivery and mitigates ARIA
2025 · Michelle E. Pizzo, Edward D. Plowey, et al. · Science · 59
Interactions between the Orbitofrontal Cortex and the Hippocampal Memory System during the Storage of Long‐Term Memory
2007 · SETH J. RAMUS, JENA B DAVIS, et al. · Annals of the New York Academy of Sciences · 52
Targeting Transferrin Receptor to Transport Antisense Oligonucleotides Across the Blood-Brain Barrier
2023 · Scarlett J Barker, Mai B Thayer, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 21
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Engineering anti-amyloid antibodies with transferrin receptor targeting improves brain biodistribution and mitigates ARIA
2024 · Michelle E. Pizzo, Edward D. Plowey, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 12
Transferrin receptor-mediated transport at the blood-brain barrier is elevated during early development and maintained across aging and in an Alzheimer’s mouse model
2025 · Vanessa O Torres, Michelle E Pizzo, et al. · Journal of Cerebral Blood Flow & Metabolism · 9
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Fc-engineered large molecules targeting blood-brain barrier transferrin receptor and CD98hc have distinct central nervous system and peripheral biodistribution compared to standard antibodies
2024 · Nathalie Khoury, Michelle E Pizzo, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 7
186. Translating an Optogenetic Gene Therapy Approach for Treatment of Neuropathic Pain in Humans
2016 · Chris Towne, Jesus Aguado, et al. · Molecular Therapy · 1
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Author Correction: Fc-engineered large molecules targeting blood-brain barrier transferrin receptor and CD98hc have distinct central nervous system and peripheral biodistribution
2026 · Nathalie Khoury, Michelle E. Pizzo, et al. · Nature Communications
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ETV:SGSH, a brain-penetrant enzyme transport vehicle for SGSH, improves lysosomal and microglial morphology, degeneration and cognitive behavior in MPS IIIA mice
2024 · Shababa T. Masoud, Hoang Nguyen, et al. · Molecular Genetics and Metabolism
Works count: 12
Citation count: 452
H-index: 8
I10-index: 7
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