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Lori G. Morton
Observed names:
L G Morton,
Lori G MORTON,
Lori Morton,
Morton, Lori
Institution:
Regeneron (United States)
Observed institutions:
Regeneron (United States),
University of Manchester,
Massachusetts General Hospital,
University of Pennsylvania
ORCID:
0000-0002-5214-5784
Observed ORCID:
0000-0002-5214-5784
OpenAlex ID:
A5012803254
Defining the Activated Fibroblast Population in Lung Fibrosis Using Single-Cell Sequencing
2019
·
Rebecca Peyser
, Scott MacDonnell
, et al.
·
American Journal of Respiratory Cell and Molecular Biology
·
205
Single-cell multi-omic and spatial profiling of human kidneys implicates the fibrotic microenvironment in kidney disease progression
2024
·
Amin Abedini
, Jonathan Levinsohn
, et al.
·
Nature Genetics
·
200
PDF
Urinary Single-Cell Profiling Captures the Cellular Diversity of the Kidney
2021
·
Amin Abedini
, Yuan O. Zhu
, et al.
·
Journal of the American Society of Nephrology
·
111
Genome-wide association analysis provides insights into the molecular etiology of dilated cardiomyopathy
2024
·
Sean L. Zheng
, Albert Henry
, et al.
·
Nature Genetics
·
64
PDF
Genome-wide association study meta-analysis provides insights into the etiology of heart failure and its subtypes
2025
·
Albert Henry
, Xiaodong Mo
, et al.
·
Nature Genetics
·
58
Inhibition of complement pathway activation with Pozelimab, a fully human antibody to complement component C5
2020
·
Adrianna Latuszek
, Yashu Liu
, et al.
·
PLoS ONE
·
46
PDF
Spatially resolved human kidney multi-omics single cell atlas highlights the key role of the fibrotic microenvironment in kidney disease progression
2022
·
Amin Abedini
, Jonathan Levinsohn
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
43
PDF
The Association between Factor XI Deficiency and the Risk of Bleeding, Cardiovascular, and Venous Thromboembolic Events
2021
·
Sarah Sharman Moser
, Gabriel Chodick
, et al.
·
Thrombosis and Haemostasis
·
42
PDF
Rationale and design of the Transformative Research in Diabetic Nephropathy (TRIDENT) Study
2019
·
Raymond R. Townsend
, Paolo Guarnieri
, et al.
·
Kidney International
·
35
Pharmacokinetics and pharmacodynamics of pozelimab alone or in combination with cemdisiran in non-human primates
2022
·
Kishor Devalaraja-Narashimha
, Cong Huang
, et al.
·
PLoS ONE
·
22
PDF
A Randomized, Double-Blind, Placebo-Controlled Phase 1 Study of the Pharmacokinetics and Pharmacodynamics of REGN3918, a Human Antibody Against Complement Factor C5, in Healthy Volunteers
2018
·
Jonathan Weyne
, Yan Ni
, et al.
·
Blood
·
20
Association of complement pathways with COVID-19 severity and outcomes
2022
·
Kishor Devalaraja-Narashimha
, Peter J. Ehmann
, et al.
·
Microbes and Infection
·
17
Activin A directly impairs human cardiomyocyte contractile function indicating a potential role in heart failure development
2022
·
Scott MacDonnell
, Jake Megna
, et al.
·
Frontiers in Cardiovascular Medicine
·
14
PDF
Humanized C3 Mouse: A Novel Accelerated Model of C3 Glomerulopathy
2020
·
Kishor Devalaraja-Narashimha
, Karoline Meagher
, et al.
·
Journal of the American Society of Nephrology
·
14
Development of a semi-automated segmentation tool for high frequency ultrasound image analysis of mouse echocardiograms
2021
·
Kristi Powers
, Raymond Chang
, et al.
·
Scientific Reports
·
11
PDF
The Activin/FLRG Pathway Associates with Poor COVID-19 Outcomes in Hospitalized Patients
2021
·
Megan McAleavy
, Qian Zhang
, et al.
·
Molecular and Cellular Biology
·
9
PDF
Pozelimab, a Human Antibody Against Complement Factor C5, Demonstrates Robust Inhibition of Alternative Complement Activity Both in Normal Human Serum and in Phase I Normal Healthy Volunteers
2019
·
Kishor Devalaraja-Narashimha
, Yan G Ni
, et al.
·
Blood
·
9
Targeted proteomic profiling of cardiogenic shock in the cardiac intensive care unit
2024
·
Siddharth M Patel
, Mathew S Lopes
, et al.
·
European Heart Journal Acute Cardiovascular Care
·
8
Pozelimab, a Human Monoclonal Antibody Against Complement Factor C5, Provided Inhibition of Intravascular Hemolysis in Patients with Paroxysmal Nocturnal Hemoglobinuria
2021
·
Jun-Ho Jang
, Jonathan Weyne
, et al.
·
Blood
·
8
Activin A correlates with the worst outcomes in COVID-19 patients, and can be induced by cytokines via the IKK/NF-kappa B pathway
2021
·
Megan McAleavy
, Qian Zhang
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
8
PDF
Interplay of procoagulatory and neutrophil-derived anticoagulatory proteins in C1q-NET–driven blood coagulation
2025
·
Minnah Thomas
, Davor Frleta
, et al.
·
Blood
·
7
Defining a Unique Gene Expression Profile in Mature and Developing Keloids
2023
·
Yuan O. Zhu
, Scott MacDonnell
, et al.
·
JID Innovations
·
7
PDF
Mapping the aetiological foundations of the heart failure spectrum using human genetics
2023
·
Albert Henry
, Xiaodong Mo
, et al.
·
medRxiv
·
6
PDF
Kappa-on-Heavy (KoH) bodies are a distinct class of fully-human antibody-like therapeutic agents with antigen-binding properties
2019
·
Lynn E. Macdonald
, Karoline A. Meagher
, et al.
·
Proceedings of the National Academy of Sciences
·
6
PDF
Interim Analysis of an Open-Label, Ascending-Dose, Phase 1 Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Doses of the Subcutaneously Administered Human Monoclonal Antibody Pozelimab in Combination with Single Doses of the Subcutaneously Administered siRNA Cemdisiran in Healthy Volunteers
2021
·
Tavé van Zyl
, Jonathan Weyne
, et al.
·
Blood
·
3
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Works count:
48
Citation count:
1,043
H-index:
14
I10-index:
16
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