Author

Diana Gikunju

Observed name: Gikunju, Diana

Observed institution: Pfizer (United States)

OpenAlex ID: A5012885746

Machine Learning on DNA-Encoded Libraries: A New Paradigm for Hit Finding

2020 · Kevin McCloskey, Eric A. Sigel, et al. · Journal of Medicinal Chemistry · 163

Encoded Library Synthesis Using Chemical Ligation and the Discovery of sEH Inhibitors from a 334-Million Member Library

2015 · Alexander Litovchick, Christoph E. Dumelin, et al. · Scientific Reports · 100

Uptake, Efficacy, and Systemic Distribution of Naked, Inhaled Short Interfering RNA (siRNA) and Locked Nucleic Acid (LNA) Antisense

2011 · Sterghios A Moschos, Manfred Frick, et al. · Molecular Therapy · 84

Discovery of a Potent BTK Inhibitor with a Novel Binding Mode by Using Parallel Selections with a DNA‐Encoded Chemical Library

2017 · John W. Cuozzo, Diana Gikunju, et al. · ChemBioChem · 82

Bispecific Estrogen Receptor α Degraders Incorporating Novel Binders Identified Using DNA-Encoded Chemical Library Screening

2021 · Jeremy S. Disch, Jennifer M. Duffy, et al. · Journal of Medicinal Chemistry · 71

Generating Selective Leads for Mer Kinase Inhibitors—Example of a Comprehensive Lead-Generation Strategy

2021 · J. Willem M. Nissink, Sana Bazzaz, et al. · Journal of Medicinal Chemistry · 30

Identification and Evaluation of Reversible Covalent Binders to Cys55 of Bfl-1 from a DNA-Encoded Chemical Library Screen

2024 · Simon C. C. Lucas, J. Henry Blackwell, et al. · ACS Medicinal Chemistry Letters · 22

Discovery of Small Molecule Interleukin 17A Inhibitors with Novel Binding Mode and Stoichiometry: Optimization of DNA-Encoded Chemical Library Hits to In Vivo Active Compounds

2024 · Ashley L. Ramos, Eric R. Goedken, et al. · Journal of Medicinal Chemistry · 19

The Design, Synthesis and Potential Utility of Fluorescence Probes that Target DFG‐out Conformation of p38α for High Throughput Screening Binding Assay

2009 · Haile Tecle, Frederic Feru, et al. · Chemical Biology & Drug Design · 11

Discovery of Small-Molecule Ligands for the E3 Ligase STUB1/CHIP from a DNA-Encoded Library Screen

2025 · Simon C. C. Lucas, Alexander G. Milbradt, et al. · ACS Medicinal Chemistry Letters · 9

Abstract C049: Identification of novel K-Ras G12C inhibitors using a DNA encoded library platform

2019 · Shilpi Arora, Chris Hupp, et al. · Molecular Cancer Therapeutics · 5

Abstract 4453: Novel, potent, and selective small-molecule inhibitors modulating immuno-oncology targets CD73, A2A/A2B adenosine receptors and CSF1R discovered via DNA-encoded library screening

2019 · Andrew J. McRiner, Jannik N. Andersen, et al. · Cancer Research · 2

Abstract 4453: Novel, potent, and selective small-molecule inhibitors modulating immuno-oncology targets CD73, A2A/A2Badenosine receptors and CSF1R discovered via DNA-encoded library screening

2019 · Andrew J. McRiner, Jannik N. Andersen, et al. · Cancer Chemistry · 2

A molecular stabiliser of an inhibitory eIF2B-eIF2(αP) complex activates the Integrated Stress Response

2026 · Fiona Shilliday, Miguel Gancedo-Rodrigo, et al. · Nature Communications · 1

Corrigendum: Discovery of a Potent BTK Inhibitor with a Novel Binding Mode by Using Parallel Selections with a DNAEncoded Chemical Library

2017 · John W. Cuozzo, Diana Gikunju, et al. · ChemBioChem · 1

Abstract 5346: Discovery of new targeted protein degraders using DNA-encoded chemistry

2023 · Anthony D. Keefe, Jeremy S. Disch, et al. · Cancer Research

Inside Cover: Discovery of a Potent BTK Inhibitor with a Novel Binding Mode by Using Parallel Selections with a DNA‐Encoded Chemical Library (ChemBioChem 9/2017)

2017 · John W. Cuozzo, Diana Gikunju, et al. · ChemBioChem

Works count: 21

Citation count: 602

H-index: 9

I10-index: 9