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Jim Warwicker

Observed names: J WARWICKER, J Warwicker, J. Warwicker, James Warwicker, Warwicker, J, Warwicker, James; id_orcid 0000-0002-1302-0815, Warwicker, Jim
Observed institutions: Howard Hughes Medical Institute, University of Alberta, University of Zurich, Biotechnology and Biological Sciences Research Council, Manchester Academic Health Science Centre, Daresbury Laboratory, University of Manchester, Quadram Institute, University of Alabama at Birmingham, Yale University, University of Bristol, University of Glasgow
ORCID: 0000-0002-1302-0815
Observed ORCID: 0000-0002-1302-0815
OpenAlex ID: A5012922833
Calculation of the electric potential in the active site cleft due to α-helix dipoles
1982 · J. Warwicker, H.C. Watson · Journal of Molecular Biology · 933
Protein–Sol: a web tool for predicting protein solubility from sequence
2017 · Max Hebditch, M Alejandro Carballo-Amador, et al. · Bioinformatics · 897
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The RACK1 Scaffold Protein: A Dynamic Cog in Cell Response Mechanisms
2002 · Angela McCahill, Jim Warwicker, et al. · Molecular Pharmacology · 390
Progress in the prediction of p K a values in proteins
2011 · Emil Alexov, Ernest L. Mehler, et al. · Proteins Structure Function and Bioinformatics · 268
The Role of Electrostatics in Protein–Protein Interactions of a Monoclonal Antibody
2014 · D. Roberts, R. Keeling, et al. · Molecular Pharmaceutics · 196
The transcriptional regulator CprK detects chlorination by combining direct and indirect readout mechanisms
2013 · Laura R. Kemp, Mark S. Dunstan, et al. · Philosophical Transactions of the Royal Society B Biological Sciences · 182
Specific Ion and Buffer Effects on Protein–Protein Interactions of a Monoclonal Antibody
2014 · D. Roberts, R. Keeling, et al. · Molecular Pharmaceutics · 178
TAPAS-1, a Novel Microdomain within the Unique N-terminal Region of the PDE4A1 cAMP-specific Phosphodiesterase That Allows Rapid, Ca2+-triggered Membrane Association with Selectivity for Interaction with Phosphatidic Acid
2002 · George S. Baillie, Elaine Huston, et al. · Journal of Biological Chemistry · 160
Visualization of poly(ADP-ribose) bound to PARG reveals inherent balance between exo- and endo-glycohydrolase activities
2013 · Eva Barkauskaite, Amy Brassington, et al. · Nature Communications · 154
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Effect of Phosphorylation on α-Helix Stability as a Function of Position
2002 · Charles D. Andrew, Jim Warwicker, et al. · Biochemistry · 136
Buried Charged Surface in Proteins
2000 · Tommi Kajander, Peter C. Kahn, et al. · Structure · 134
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Web-based display of protein surface and pH-dependent properties for assessing the developability of biotherapeutics
2019 · Max Hebditch, Jim Warwicker · Scientific Reports · 110
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Charged residues next to transmembrane regions revisited: “Positive-inside rule” is complemented by the “negative inside depletion/outside enrichment rule”
2017 · James Alexander Baker, Wing-Cheong Wong, et al. · BMC Biology · 99
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Improved pKa calculations through flexibility based sampling of a water‐dominated interaction scheme
2004 · Jim Warwicker · Protein Science · 95
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Current advances in biopharmaceutical informatics: guidelines, impact and challenges in the computational developability assessment of antibody therapeutics
2022 · Rahul Khetan, Robin Curtis, et al. · mAbs · 94
Soluble expression of proteins correlates with a lack of positively-charged surface
2013 · Pedro Chan, Robin A. Curtis, et al. · Scientific Reports · 94
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Simplified methods for pKa and acid pH‐dependent stability estimation in proteins: Removing dielectric and counterion boundaries
1999 · James Warwicker · Protein Science · 90
Side‐chain conformational entropy at protein–protein interfaces
2002 · Christian Cole, Jim Warwicker · Protein Science · 84
Lysine and Arginine Content of Proteins: Computational Analysis Suggests a New Tool for Solubility Design
2013 · Jim Warwicker, Spyros Charonis, et al. · Molecular Pharmaceutics · 78
A Quantitative Molecular Model for Modulation of Mammalian Translation by the eIF4E-binding Protein 1
2001 · Muhammad Manjurul Karim, John M.X. Hughes, et al. · Journal of Biological Chemistry · 78
Mechanisms for stabilisation and the maintenance of solubility in proteins from thermophiles
2007 · Richard B Greaves, Jim Warwicker · BMC Structural Biology · 75
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Electrostatic calculations and model‐building suggest that DNA bound to CAP is sharply bent
1987 · J. Warwicker, B.P. Engelman, et al. · Proteins Structure Function and Bioinformatics · 74
A molecular model for the redox potential difference between thioredoxin and DsbA, based on electrostatics calculations
1995 · P.J. Gane, R.B. Freedman, et al. · Journal of Molecular Biology · 71
Electrostatic field of the large fragment of Escherichia coli DNA polymerase I
1985 · J. Warwicker, D. Ollis, et al. · Journal of Molecular Biology · 70
Continuum dielectric modelling of the protein-solvent system, and calculation of the long-range electrostatic field of the enzyme phosphoglycerate mutase
1986 · J. Warwicker · Journal of Theoretical Biology · 67
Works count: 201
Citation count: 7,020
H-index: 42
I10-index: 96
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