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Frederick W. Gergits
Observed names:
F.W. Gergits,
Frederick Gergits
Observed institutions:
Boston Children's Hospital,
Harvard University,
Watertown City School District
OpenAlex ID:
A5013028964
Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes
2018
·
Timothy R. Hammond
, Connor Dufort
, et al.
·
Immunity
·
2,201
PDF
Microglia and complement mediate early corticostriatal synapse loss and cognitive dysfunction in Huntington’s disease
2023
·
Daniel K. Wilton
, Kevin Mastro
, et al.
·
Nature Medicine
·
172
CSMD1 regulates brain complement activity and circuit development
2024
·
Matthew L. Baum
, Daniel K. Wilton
, et al.
·
Brain Behavior and Immunity
·
47
CUB and Sushi Multiple Domains 1 (CSMD1) opposes the complement cascade in neural tissues
2020
·
Matthew L. Baum
, Daniel K. Wilton
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
25
PDF
Rescue of in vitro models of CSF1R-related adult-onset leukodystrophy by iluzanebart: mechanisms and therapeutic implications of TREM2 agonism
2025
·
Kelley C. Larson
, Frederick W. Gergits
, et al.
·
Journal of Neuroinflammation
·
13
PDF
Pharmacological and functional characterization of the first small molecule TREM2 agonist, VG‐3927, for the treatment of Alzheimer’s disease
2024
·
Christian Mirescu
, Borislav Dejanovic
, et al.
·
Alzheimer s & Dementia
·
10
PDF
A Fast-Binding, Functionally Reversible, COX‑2 Radiotracer for CNS PET Imaging
2024
·
Michael S. Placzek
, Daniel K. Wilton
, et al.
·
ACS Central Science
·
9
VGL101 Rescues CSF1R Dysfunction in Human Microglia And Macrophages: Evaluation of In Vitro Trem2 Agonism in Models Of A CSF1R‐Dependent Leukodystrophy
2022
·
Kelley C. Larson
, Frederick Gergits
, et al.
·
Alzheimer s & Dementia
·
5
Microglia Mediate Early Corticostriatal Synapse Loss and Cognitive Dysfunction in Huntington’s Disease Through Complement-Dependent Mechanisms
2021
·
D.K. Wilton
, K. Mastro
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
5
PDF
VGL101: An Immunotherapy that Enhances Microglial Survival for Adult-onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia (ALSP) (P9-9.013)
2024
·
Kelley C. Larson
, Frederick W. Gergits
, et al.
·
Neurology
·
1
Preclinical and first-in-human evaluation of VG-3927/SAR448851, an oral small-molecule TREM2 agonist for Alzheimer’s disease
2026
·
Borislav Dejanovic
, Matthew D. Figley
, et al.
·
Science Translational Medicine
Author Correction: Microglia and complement mediate early corticostriatal synapse loss and cognitive dysfunction in Huntington’s disease
2023
·
Daniel K. Wilton
, Kevin Mastro
, et al.
·
Nature Medicine
PDF
Characterizing microglial interactions with cortical neurons during development of the healthy brain
2017
·
Frederick Gergits
·
Digital WPI
PDF
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Works count:
12
Citation count:
2,484
H-index:
7
I10-index:
6
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