Author

Fucheng Yin

Observed names: Fu-Cheng Yin, Fucheng YIN

Observed institutions: China Pharmaceutical University, State Key Laboratory of Natural Medicine, University of South China

ORCID: 0000-0002-9999-6367

Observed ORCID: 0000-0002-9999-6367

OpenAlex ID: A5013041000

Progress in approved drugs from natural product resources

2024 · Zhongwen LUO, Fucheng YIN, et al. · Chinese Journal of Natural Medicines · 215

Discovery of First-in-Class Dual PARP and EZH2 Inhibitors for Triple-Negative Breast Cancer with Wild-Type BRCA

2021 · Cheng Wang, Lailiang Qu, et al. · Journal of Medicinal Chemistry · 92

Development of a Tau-Targeted Drug Delivery System Using a Multifunctional Nanoscale Metal–Organic Framework for Alzheimer’s Disease Therapy

2020 · Jinhua Zhao, Fucheng Yin, et al. · ACS Applied Materials & Interfaces · 86

Discovery of precision targeting EZH2 degraders for triple-negative breast cancer

2022 · Cheng Wang, Xinye Chen, et al. · European Journal of Medicinal Chemistry · 59

Discovery of PT-65 as a highly potent and selective Proteolysis-targeting chimera degrader of GSK3 for treating Alzheimer's disease

2021 · Lailiang Qu, Shang Li, et al. · European Journal of Medicinal Chemistry · 57

Chromone and donepezil hybrids as new multipotent cholinesterase and monoamine oxidase inhibitors for the potential treatment of Alzheimer's disease

2020 · Xiao-Bing Wang, Fu-Cheng Yin, et al. · RSC Medicinal Chemistry · 51

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Synthesis and evaluation of multi-target-directed ligands with BACE-1 inhibitory and Nrf2 agonist activities as potential agents against Alzheimer’s disease

2021 · Lailiang Qu, Limei Ji, et al. · European Journal of Medicinal Chemistry · 43

Design and SAR of Withangulatin A Analogues that Act as Covalent TrxR Inhibitors through the Michael Addition Reaction Showing Potential in Cancer Treatment

2020 · Cheng Wang, Shang Li, et al. · Journal of Medicinal Chemistry · 42

Histone Deacetylase and Enhancer of Zeste Homologue 2 Dual Inhibitors Presenting a Synergistic Effect for the Treatment of Hematological Malignancies

2022 · Dehua Lu, Cheng Wang, et al. · Journal of Medicinal Chemistry · 39

Two types of coumarins-specific enzymes complete the last missing steps in pyran- and furanocoumarins biosynthesis

2023 · Yucheng Zhao, Yuedong He, et al. · Acta Pharmaceutica Sinica B · 37

Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer

2021 · Xingchen Liu, Cheng Wang, et al. · Journal of Medicinal Chemistry · 33

A hemicyanine derivative for near-infrared imaging of β-amyloid plaques in Alzheimer's disease

2019 · Hua-Li Yang, Si-Qiang Fang, et al. · European Journal of Medicinal Chemistry · 31

Identification and optimization of piperlongumine analogues as potential antioxidant and anti-inflammatory agents via activation of Nrf2

2020 · Limei Ji, Lailiang Qu, et al. · European Journal of Medicinal Chemistry · 30

Optimization of WZ4003 as NUAK inhibitors against human colorectal cancer

2020 · Huali Yang, Xiaobing Wang, et al. · European Journal of Medicinal Chemistry · 28

Dual target PARP1/EZH2 inhibitors inducing excessive autophagy and producing synthetic lethality for triple-negative breast cancer therapy

2023 · Xinxin Li, Cheng Wang, et al. · European Journal of Medicinal Chemistry · 25

Discovery of dual PARP and CDK6 inhibitors for triple-negative breast cancer with wild-type BRCA

2023 · Cheng Wang, Heng Luo, et al. · Bioorganic Chemistry · 24

Harmine-based dual inhibitors targeting histone deacetylase (HDAC) and DNA as a promising strategy for cancer therapy

2022 · Dehua Lu, Lailiang Qu, et al. · Bioorganic Chemistry · 23

Palladium-Catalyzed meta-C–H Olefination of Arene-Tethered Diols Directed by Well-Designed Pyrimidine-Based Group

2019 · Siqiang Fang, Xiaobing Wang, et al. · Organic Letters · 22

Design and Synthesis of PARP/CDK6 Dual-Target Inhibitors Modulating of Wnt/β-Catenin Signaling Pathway for the Treatment of BRCA Wild-Type TNBC

2025 · Yonglei Zhang, Fucheng Yin, et al. · Journal of Medicinal Chemistry · 20

Discovery of Dual CDK6/BRD4 Inhibitor Inducing Apoptosis and Increasing the Sensitivity of Ferroptosis in Triple-Negative Breast Cancer

2024 · Yonglei Zhang, Long Zheng, et al. · Journal of Medicinal Chemistry · 20

Oxazole-4-carboxamide/butylated hydroxytoluene hybrids with GSK-3β inhibitory and neuroprotective activities against Alzheimer's disease

2023 · Zhongwen Luo, Shang Li, et al. · European Journal of Medicinal Chemistry · 16

Discovery, Structure, and Mechanism of the (R, S)-Norcoclaurine Synthase for the Chiral Synthesis of Benzylisoquinoline Alkaloids

2023 · Libo Zhang, Shiqing Zhang, et al. · ACS Catalysis · 15

Discovery of Covalent MLKL PROTAC Degraders via Optimization of a Theophylline Derivative Ligand for Treating Necroptosis

2024 · Shang Li, Liangliang Ma, et al. · Journal of Medicinal Chemistry · 14

Design, Synthesis, and Biological Evaluation of Novel Quinoline Derivatives Containing 1,3,4-Oxadiazole Moieties as Potential Antifungal Agents

2025 · Fucheng Yin, Hang Liu, et al. · Journal of Agricultural and Food Chemistry · 13

Rhodium( iii ) catalyzed olefination and deuteration of tetrahydrocarbazole

2021 · Wan Peng, Qiaohong Liu, et al. · RSC Advances · 11

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Works count: 36

Citation count: 1,083

H-index: 20

I10-index: 25