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Jan A. Ehses

Observed names: Ehses, J A, Ehses, J.A., Ehses, Jan, Ehses, Jan A., J Ehses, J. A. Ehses, J. Ehses, J.A. Ehses, Jan A Ehses, Jan Adam Ehses, Jan Ehses, Jan A. Ehses
Observed institutions: University of British Columbia, University of Zurich, ETH Zurich, University Hospital Zurich, Child and Family Research Institute, Institute of Food, Nutrition, and Health, BC Children's Hospital Research Institute
ORCID: 0000-0001-9066-7607
Observed ORCID: 0000-0001-9066-7607
OpenAlex ID: A5013450317
Interleukin-1–Receptor Antagonist in Type 2 Diabetes Mellitus
2007 · Claus M. Larsen, Mirjam Faulenbach, et al. · New England Journal of Medicine · 1,799
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Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells
2011 · Helga Ellingsgaard, Irina Hauselmann, et al. · Nature Medicine · 923
Increased Number of Islet-Associated Macrophages in Type 2 Diabetes
2007 · Jan A. Ehses, Aurel Perren, et al. · Diabetes · 783
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Mechanisms of β-Cell Death in Type 2 Diabetes
2005 · Marc Y. Donath, Jan A. Ehses, et al. · Diabetes · 445
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Sustained Effects of Interleukin-1 Receptor Antagonist Treatment in Type 2 Diabetes
2009 · Claus M. Larsen, Mirjam Faulenbach, et al. · Diabetes Care · 403
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IL-1 antagonism reduces hyperglycemia and tissue inflammation in the type 2 diabetic GK rat
2009 · J. A. Ehses, G. Lacraz, et al. · Proceedings of the National Academy of Sciences · 347
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Free Fatty Acids Induce a Proinflammatory Response in Islets via the Abundantly Expressed Interleukin-1 Receptor I
2009 · Marianne Böni-Schnetzler, Simone Boller, et al. · Endocrinology · 339
Islet Inflammation in Type 2 Diabetes
2008 · Marc Y. Donath, Desiree M. Schumann, et al. · Diabetes Care · 334
Dipeptidyl Peptidase IV Inhibitor Treatment Stimulates β-Cell Survival and Islet Neogenesis in Streptozotocin-Induced Diabetic Rats
2003 · J. Andrew Pospisilik, Jennifer Martin, et al. · Diabetes · 332
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Islet Inflammation Impairs the Pancreatic β-Cell in Type 2 Diabetes
2009 · Marc Y. Donath, Marianne Böni-Schnetzler, et al. · Physiology · 330
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Increased Interleukin (IL)-1β Messenger Ribonucleic Acid Expression in β-Cells of Individuals with Type 2 Diabetes and Regulation of IL-1β in Human Islets by Glucose and Autostimulation
2008 · Marianne Böni-Schnetzler, Jeffrey Thorne, et al. · The Journal of Clinical Endocrinology & Metabolism · 320
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Interleukin-6 regulates pancreatic α-cell mass expansion
2008 · Helga Ellingsgaard, Jan A. Ehses, et al. · Proceedings of the National Academy of Sciences · 269
Leptin modulates β cell expression of IL-1 receptor antagonist and release of IL-1β in human islets
2004 · Kathrin Maedler, Pavel Sergeev, et al. · Proceedings of the National Academy of Sciences · 249
Low- and High-Density Lipoproteins Modulate Function, Apoptosis, and Proliferation of Primary Human and Murine Pancreatic β-Cells
2009 · Sabine Rütti, Jan A. Ehses, et al. · Endocrinology · 237
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Cytokine production by islets in health and diabetes: cellular origin, regulation and function
2010 · Marc Y. Donath, Marianne Böni-Schnetzler, et al. · Trends in Endocrinology and Metabolism · 227
Resident Macrophages Mediate Islet Amyloid Polypeptide–Induced Islet IL-1β Production and β-Cell Dysfunction
2013 · Clara Y. Westwell-Roper, Jan A. Ehses, et al. · Diabetes · 224
Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet
2010 · J. A. Ehses, D. T. Meier, et al. · Diabetologia · 222
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IL-1 Blockade Attenuates Islet Amyloid Polypeptide-Induced Proinflammatory Cytokine Release and Pancreatic Islet Graft Dysfunction
2011 · Clara Westwell-Roper, Derek L Dai, et al. · The Journal of Immunology · 190
Glucose-Dependent Insulinotropic Polypeptide Promotes β-(INS-1) Cell Survival via Cyclic Adenosine Monophosphate-Mediated Caspase-3 Inhibition and Regulation of p38 Mitogen-Activated Protein Kinase
2003 · Jan A. Ehses, Vanbric R. Casilla, et al. · Endocrinology · 159
Insulin Inhibits IL-10–Mediated Regulatory T Cell Function: Implications for Obesity
2013 · Jonathan M Han, Scott J Patterson, et al. · The Journal of Immunology · 156
Interleukin-6 Delays Gastric Emptying in Humans with Direct Effects on Glycemic Control
2018 · Louise Lang Lehrskov, Mark Preben Lyngbaek, et al. · Cell Metabolism · 135
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Glucose-dependent Insulinotropic Polypeptide Activates the Raf-Mek1/2-ERK1/2 Module via a Cyclic AMP/cAMP-dependent Protein Kinase/Rap1-mediated Pathway
2002 · Jan A. Ehses, Steven L. Pelech, et al. · Journal of Biological Chemistry · 133
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Glucose-dependent insulinotropic polypeptide receptor null mice exhibit compensatory changes in the enteroinsular axis
2003 · Nathalie Pamir, Francis C. Lynn, et al. · American Journal of Physiology-Endocrinology and Metabolism · 126
TLR2/6 and TLR4-activated macrophages contribute to islet inflammation and impair beta cell insulin gene expression via IL-1 and IL-6
2014 · Dominika Nackiewicz, Meixia Dan, et al. · Diabetologia · 123
Pancreatic islet inflammation in type 2 diabetes: From α and β cell compensation to dysfunction
2009 · Jan A. Ehses, Helga Ellingsgaard, et al. · Archives of Physiology and Biochemistry · 97
Works count: 78
Citation count: 10,080
H-index: 37
I10-index: 54
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