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Barbara Forte
Observed name:
B. Forte
Institution:
University of Dundee
Observed institutions:
University of Dundee,
Wellcome Centre for Anti-Infectives Research,
Nerviano Medical Sciences,
University of Turin
ORCID:
0000-0003-3986-5880
Observed ORCID:
0000-0003-3986-5880
OpenAlex ID:
A5013685136
1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazoles: Identification of a Potent Aurora Kinase Inhibitor with a Favorable Antitumor Kinase Inhibition Profile
2006
·
Daniele Fancelli
, Jürgen Moll
, et al.
·
Journal of Medicinal Chemistry
·
188
Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis
2019
·
Beatriz Baragaña
, Barbara Forte
, et al.
·
Proceedings of the National Academy of Sciences
·
147
PDF
Potent and Selective Aurora Inhibitors Identified by the Expansion of a Novel Scaffold for Protein Kinase Inhibition
2005
·
Daniele Fancelli
, Daniela Berta
, et al.
·
Journal of Medicinal Chemistry
·
146
Discovery of 2-[1-(4,4-Difluorocyclohexyl)piperidin-4-yl]-6-fluoro-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide (NMS-P118): A Potent, Orally Available, and Highly Selective PARP-1 Inhibitor for Cancer Therapy
2015
·
Gianluca Papeo
, Helena Posteri
, et al.
·
Journal of Medicinal Chemistry
·
141
NMS-P937, a 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivative as potent and selective Polo-like kinase 1 inhibitor
2011
·
Italo Beria
, Roberto T. Bossi
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
105
Prioritization of Molecular Targets for Antimalarial Drug Discovery
2021
·
Barbara Forte
, Sabine Ottilie
, et al.
·
ACS Infectious Diseases
·
84
Small-Molecule Antibiotic Drug Development: Need and Challenges
2023
·
Megan Bergkessel
, Barbara Forte
, et al.
·
ACS Infectious Diseases
·
70
PDF
First Cdc7 Kinase Inhibitors: Pyrrolopyridinones as Potent and Orally Active Antitumor Agents. 2. Lead Discovery
2008
·
Maria Menichincheri
, Alberto Bargiotti
, et al.
·
Journal of Medicinal Chemistry
·
66
Cdc7 Kinase Inhibitors: 5-Heteroaryl-3-Carboxamido-2-Aryl Pyrroles as Potential Antitumor Agents. 1. Lead Finding
2010
·
Maria Menichincheri
, Clara Albanese
, et al.
·
Journal of Medicinal Chemistry
·
62
Biochemical and Structural Characterization of Selective Allosteric Inhibitors of the Plasmodium falciparum Drug Target, Prolyl-tRNA-synthetase
2016
·
Stephen Nakazawa Hewitt
, David M. Dranow
, et al.
·
ACS Infectious Diseases
·
52
Poly(ADP-ribose) polymerase inhibition in cancer therapy: are we close to maturity?
2009
·
Gianluca Papeo
, Barbara Forte
, et al.
·
Expert Opinion on Therapeutic Patents
·
37
Structural Insight into Maternal Embryonic Leucine Zipper Kinase (MELK) Conformation and Inhibition toward Structure-Based Drug Design
2013
·
Giulia Canevari
, Stefania Re Depaolini
, et al.
·
Biochemistry
·
33
Thieno[3,2-c]pyrazoles: A novel class of Aurora inhibitors with favorable antitumor activity
2010
·
Simona Bindi
, Daniele Fancelli
, et al.
·
Bioorganic & Medicinal Chemistry
·
29
Identification and Optimization of Novel Inhibitors of the Polyketide Synthase 13 Thioesterase Domain with Antitubercular Activity
2023
·
Simon R. Green
, Caroline Wilson
, et al.
·
Journal of Medicinal Chemistry
·
21
PDF
Cryptosporidium lysyl-tRNA synthetase inhibitors define the interplay between solubility and permeability required to achieve efficacy
2024
·
Nicola Caldwell
, Caroline Peet
, et al.
·
Science Translational Medicine
·
18
Revisiting the Plasmodium falciparum druggable genome using predicted structures and data mining
2025
·
Karla P. Godinez-Macias
, Daisy Chen
, et al.
·
npj Drug Discovery.
·
16
Susceptibility of Ugandan Plasmodium falciparum Isolates to the Antimalarial Drug Pipeline
2023
·
Oriana Kreutzfeld
, Patrick K. Tumwebaze
, et al.
·
Microbiology Spectrum
·
10
PDF
Mycobacterium tuberculosis Phe-tRNA synthetase: structural insights into tRNA recognition and aminoacylation
2021
·
Karolina Michalska
, Robert Jedrzejczak
, et al.
·
Nucleic Acids Research
·
6
PDF
Different chemical scaffolds bind to L-phe site in Mycobacterium tuberculosis Phe-tRNA synthetase
2025
·
Priyanka Gade
, Changsoo Chang
, et al.
·
European Journal of Medicinal Chemistry
·
1
PDF
Structure of Mycobacterium tuberculosis Phe-tRNA synthetase reveals ligand binding and two-stage tRNA recognition
2020
·
Karolina Michalska
, Robert Jedrzejczak
, et al.
·
Research Square
·
1
PDF
Identification, Structure–Activity Relationship (SAR), and Biological Evaluation of New Chemical Series as Malaria Parasite Pf GCN5 Bromodomain Inhibitors
2026
·
Pedro Martin-Acosta
, Abbas H. K. Al Temimi
, et al.
·
ACS Omega
Structure-Guided Optimization of Novel Inhibitors of Plasmodium Lysyl-tRNA Synthetase with Multistage Activity against Malaria Parasites
2026
·
Barbara Forte
, Fiona Bellany
, et al.
·
Journal of Medicinal Chemistry
PDF
The Quest to Identify USP8 Inhibitors for Parkinson’s Disease, a PAINful Experience
2023
·
Stuart Lang
, Fiona Bellany
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
PDF
Crystal Structure of Lysyl-tRNA Synthetase from Cryptosporidium parvum complexed with L-lysine and a difluoro cyclohexyl chromone ligand
2018
·
D.A. Robinson
, B. Baragana
, et al.
·
Worldwide Protein Data Bank
Abstract 691: In vitro and in vivo characterization of selective orally available Parp-1 inhibitors with demonstrated antitumor efficacy in BRCA negative cancer models
2010
·
Gianluca Papeo
, Sonia Rainoldi
, et al.
·
Cancer Research
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Works count:
28
Citation count:
1,234
H-index:
16
I10-index:
17
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