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Chang-Rung Chen

Observed names: CHANG-RUNG CHEN, Chang-rung Chen
OpenAlex ID: A5013780845
A Self-Enabling TGFβ Response Coupled to Stress Signaling
2003 · Yibin Kang, Chang-Rung Chen, et al. · Molecular Cell · 563
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Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway
2005 · Yibin Kang, Wei He, et al. · Proceedings of the National Academy of Sciences · 537
E2F4/5 and p107 as Smad Cofactors Linking the TGFβ Receptor to c-myc Repression
2002 · Chang-Rung Chen, Yibin Kang, et al. · Cell · 495
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ARQ 197, a Novel and Selective Inhibitor of the Human c-Met Receptor Tyrosine Kinase with Antitumor Activity
2010 · Neru Munshi, Sébastien Jeay, et al. · Molecular Cancer Therapeutics · 337
Defective repression of c- myc in breast cancer cells: A loss at the core of the transforming growth factor β growth arrest program
2001 · Chang-Rung Chen, Yibin Kang, et al. · Proceedings of the National Academy of Sciences · 322
DNA Gyrase and Topoisomerase IV on the Bacterial Chromosome: Quinolone-induced DNA Cleavage
1996 · Chang-Rung Chen, Muhammad Malik, et al. · Journal of Molecular Biology · 279
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A Novel Mode of Protein Kinase Inhibition Exploiting Hydrophobic Motifs of Autoinhibited Kinases
2011 · Sudharshan Eathiraj, Rocio Palma, et al. · Journal of Biological Chemistry · 67
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Moe1, a conserved protein in Schizosaccharomyces pombe , interacts with a Ras effector, Scd1, to affect proper spindle formation
1999 · Chang-rung Chen, Ying-chun Li, et al. · Proceedings of the National Academy of Sciences · 57
Dual Induction of Apoptosis and Senescence in Cancer Cells by Chk2 Activation: Checkpoint Activation as a Strategy against Cancer
2005 · Chang-Rung Chen, Wenxian Wang, et al. · Cancer Research · 52
Fission Yeast Ras1 Effector Scd1 Interacts With the Spindle and Affects Its Proper Formation
2000 · Ying-chun Li, Chang-rung Chen, et al. · Genetics · 37
A Conserved Interaction between Moe1 and Mal3 Is Important for Proper Spindle Formation inSchizosaccharomyces pombe
2000 · Chang-Rung Chen, Jing Chen, et al. · Molecular Biology of the Cell · 33
Abstract 2750: ARQ 621, a novel potent and selective inhibitor of Eg5: Preclinical data and early results from a clinical phase 1 study
2010 · Lee Rosen, Lin-Chi Chen, et al. · Cancer Research · 7
Abstract #820: Combination studies of tyrosine kinase inhibitors (TKIs): Assessment of potential cytotoxic synergy of ARQ 197 with sorafenib or sunitinib
2009 · Chang-Rung Chen, Jeff Szwaya, et al. · Cancer Research · 7
A Novel Platform for Accelerated Pharmacodynamic Profiling for Lead Optimization of Anticancer Drug Candidates
2007 · Jeffrey Szwaya, Charles Bruseo, et al. · SLAS DISCOVERY · 7
Abstract A278: ARQ 087, a multi-tyrosine kinase inhibitor with potent in vitro and in vivo activity in FGFR2 driven models.
2013 · Daniel Dransfield, Jennifer Lee, et al. · Molecular Cancer Therapeutics · 4
Abstract A230: Discovery and characterization of ARQ 092, an ATP-independent, potent and selective inhibitor of AKT kinases.
2011 · Thomas C.K. Chan, Jean-Marc Lapierre, et al. · Molecular Cancer Therapeutics · 4
Abstract 3565: Abrogation of the paradoxical activation of the MAPK pathway following RAF inhibition by ARQ 680, a potent inhibitor of the RAF family of serine/threonine kinases
2011 · Chang-Rung Chen, Jeffrey Szwaya, et al. · Cancer Research · 2
Prokaryotic DNA topology and gene expression
1999 · Karl Drlica, Erden-Dalai Wu, et al. · Oxford University Press eBooks · 2
Abstract A281: Exploratory study on predictive biomarkers for ARQ 092, a novel selective pan-AKT inhibitor.
2013 · Yi Yu, Rebecca Carazza, et al. · Molecular Cancer Therapeutics · 1
Abstract 5376: Potentiation of the anti-proliferative and cytotoxic activity of ARQ 197 & gemcitabine with a pulsatile exposure regimen
2011 · Chang-Rung Chen, Giovanni Abbadessa, et al. · Cancer Research · 1
Abstract 3571: Exploratory biomarker discovery for clinical development of ARQ 087, a potent pan-FGFR kinase inhibitor
2011 · Yi Yu, Xiubin Gu, et al. · Cancer Research · 1
Abstract 4501: Development and biological annotation of a novel RAF inhibitor amenable for clinical evaluation against BRAF (V600E)-harboring human tumors
2010 · Chang-Rung Chen, Jean-Marc Lapierre, et al. · Cancer Research · 1
Sedimentation Analysis of Bacterial Nucleoid Structure
2003 · Karl Drlica, Chang-Rung Chen, et al. · Humana Press eBooks · 1
Supplementary Data from ARQ 197, a Novel and Selective Inhibitor of the Human c-Met Receptor Tyrosine Kinase with Antitumor Activity
2023 · Neru Munshi, Sébastien Jeay, et al.
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Data from ARQ 197, a Novel and Selective Inhibitor of the Human c-Met Receptor Tyrosine Kinase with Antitumor Activity
2023 · Neru Munshi, Sébastien Jeay, et al.
Works count: 34
Citation count: 2,817
H-index: 11
I10-index: 11
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