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Paul W. Bowyer

Observed names: Bowyer, Paul, P.W. Bowyer, Paul W Bowyer, Paul W. Bowyer, Paul W. Bowyer
Observed institutions: London School of Hygiene & Tropical Medicine, Stanford Medicine, Medicines and Healthcare products Regulatory Agency, Imperial College London, National Institute for Biological Standards and Control, Stanford University
ORCID: 0000-0002-4046-9191
Observed ORCID: 0000-0002-4046-9191
OpenAlex ID: A5014098742
A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission
2017 · David A. Baker, Lindsay B. Stewart, et al. · Nature Communications · 171
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Proteomic Analysis of Fractionated Toxoplasma Oocysts Reveals Clues to Their Environmental Resistance
2012 · Heather M. Fritz, Paul W. Bowyer, et al. · PLoS ONE · 146
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Dual acylation of the 45kDa gliding-associated protein (GAP45) in Plasmodium falciparum merozoites
2006 · Roxanne R. Rees-Channer, Stephen R. Martin, et al. · Molecular and Biochemical Parasitology · 109
Site-specific N-terminal labelling of proteinsin vitro and in vivo using N-myristoyl transferase and bioorthogonal ligation chemistry
2007 · William P. Heal, Sasala R. Wickramasinghe, et al. · Chemical Communications · 89
Molecules incorporating a benzothiazole core scaffold inhibit the N-myristoyltransferase of Plasmodium falciparum
2007 · Paul W. Bowyer, Ruwani S. Gunaratne, et al. · Biochemical Journal · 66
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N‐Myristoyltransferase: a Prospective Drug Target for Protozoan Parasites
2008 · Paul W. Bowyer, Edward W. Tate, et al. · ChemMedChem · 65
Small-molecule inhibition of a depalmitoylase enhances Toxoplasma host-cell invasion
2013 · Matthew A Child, Carolyn I Hall, et al. · Nature Chemical Biology · 62
Global Profiling of Proteolysis during Rupture of Plasmodium falciparum from the Host Erythrocyte
2010 · Paul W. Bowyer, Gabriel M. Simon, et al. · Molecular & Cellular Proteomics · 61
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Characterization and selective inhibition of myristoyl-CoA:protein N-myristoyltransferase from Trypanosoma brucei and Leishmania major
2006 · Chrysoula Panethymitaki, Paul W. Bowyer, et al. · Biochemical Journal · 60
Chemical genetic screen identifies Toxoplasma DJ-1 as a regulator of parasite secretion, attachment, and invasion
2011 · Carolyn I. Hall, Michael L. Reese, et al. · Proceedings of the National Academy of Sciences · 59
Bradyzoite Pseudokinase 1 Is Crucial for Efficient Oral Infectivity of the Toxoplasma gondii Tissue Cyst
2013 · Kerry R. Buchholz, Paul W. Bowyer, et al. · Eukaryotic Cell · 54
Imidazopyridazine Inhibitors of Plasmodium falciparum Calcium-Dependent Protein Kinase 1 Also Target Cyclic GMP-Dependent Protein Kinase and Heat Shock Protein 90 To Kill the Parasite at Different Stages of Intracellular Development
2015 · Judith L. Green, Robert W. Moon, et al. · Antimicrobial Agents and Chemotherapy · 53
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Heterotypic interactions drive antibody synergy against a malaria vaccine candidate
2022 · Robert J. Ragotte, David Pulido, et al. · Nature Communications · 46
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The role of cGMP signalling in regulating life cycle progression of Plasmodium
2012 · Christine S. Hopp, Paul W. Bowyer, et al. · Microbes and Infection · 44
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Variation in Plasmodium falciparum Erythrocyte Invasion Phenotypes and Merozoite Ligand Gene Expression across Different Populations in Areas of Malaria Endemicity
2015 · Paul W. Bowyer, Lindsay B. Stewart, et al. · Infection and Immunity · 41
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A unique phosphatidylinositol 4-phosphate 5-kinase is activated by ADP-ribosylation factor in Plasmodium falciparum
2009 · Werner Leber, Alison Skippen, et al. · International Journal for Parasitology · 36
The establishment of a WHO Reference Reagent for anti-malaria (Plasmodium falciparum) human serum
2017 · the Collaborative study group, Donna Bryan, et al. · Malaria Journal · 27
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Trisubstituted thiazoles as potent and selective inhibitors of Plasmodium falciparum protein kinase G (PfPKG)
2018 · Denise J. Tsagris, Kristian Birchall, et al. · Bioorganic & Medicinal Chemistry Letters · 25
Cytotoxicity of human antibodies targeting the circumsporozoite protein is amplified by 3D substrate and correlates with protection
2023 · Manuela C. Aguirre-Botero, Lawrence T. Wang, et al. · Cell Reports · 24
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Potent inhibitors of malarial P. Falciparum protein kinase G: Improving the cell activity of a series of imidazopyridines
2018 · Jonathan M. Large, Kristian Birchall, et al. · Bioorganic & Medicinal Chemistry Letters · 20
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Optimization of incubation conditions of Plasmodium falciparum antibody multiplex assays to measure IgG, IgG1–4, IgM and IgE using standard and customized reference pools for sero-epidemiological and vaccine studies
2018 · Itziar Ubillos, Alfons Jiménez, et al. · Malaria Journal · 20
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Potent bicyclic inhibitors of malarial cGMP-dependent protein kinase: approaches to combining improvements in cell potency, selectivity and structural novelty
2019 · Jonathan M. Large, Kristian Birchall, et al. · Bioorganic & Medicinal Chemistry Letters · 14
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Expanding the Malaria Antibody Toolkit: Development and Characterisation of Plasmodium falciparum RH5, CyRPA, and CSP Recombinant Human Monoclonal Antibodies
2022 · Adéla Nacer, Gaily Kivi, et al. · Frontiers in Cellular and Infection Microbiology · 8
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Peptide‐based inhibitors of N‐myristoyl transferase generated from a lipid/combinatorial peptide chimera library
2006 · Edward W. Tate, Paul W. Bowyer, et al. · Signal Transduction · 6
Workshop report: Malaria vaccine development in Europe–preparing for the future
2015 · Nicola K. Viebig, Flavia D’Alessio, et al. · Vaccine · 5
Works count: 40
Citation count: 1,311
H-index: 20
I10-index: 22
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