Author

Paulina Appelkvist

Observed name: P. Appelkvist

Institution: BioArctic Neuroscience (Sweden)

Observed institutions: Uppsala University, BioArctic Neuroscience (Sweden), AstraZeneca (Sweden)

OpenAlex ID: A5014126191

Sustained peripheral depletion of amyloid-β with a novel form of neprilysin does not affect central levels of amyloid-β

2013 · Simon J. Henderson, Christin Andersson, et al. · Brain · 77

ABBV-0805, a novel antibody selective for soluble aggregated α-synuclein, prolongs lifespan and prevents buildup of α-synuclein pathology in mouse models of Parkinson's disease

2021 · Eva Nordström, Fredrik Eriksson, et al. · Neurobiology of Disease · 55

AZ-4217: A High Potency BACE Inhibitor Displaying Acute Central Efficacy in Different In Vivo Models and Reduced Amyloid Deposition in Tg2576 Mice

2013 · S. Eketjall, J. Janson, et al. · Journal of Neuroscience · 39

Decreased axonal transport rates in the Tg2576 APP transgenic mouse: improvement with the gamma‐secretase inhibitor MRK‐560 as detected by manganese‐enhanced MRI

2012 · Fu‐Hua Wang, Paulina Appelkvist, et al. · European Journal of Neuroscience · 24

Characterization of beta2-microglobulin in a primitive fish, the Siberian sturgeon ( Acipenser baeri )

1999 · Mats L. Lundqvist, Paulina Appelkvist, et al. · Immunogenetics · 24

Triazolopyrimidinones as γ-secretase modulators: structure–activity relationship, modulator profile, and in vivo profiling

2013 · Ulrika Yngve, Kim Paulsen, et al. · MedChemComm · 11

Disease modifying effects of the amyloid-beta protofibril-selective antibody mAb158 in aged Tg2576 transgenic mice

2024 · Biljana Rizoska, Olof Zachrisson, et al. · Molecular and Cellular Neuroscience · 10

Modeling of age‐dependent amyloid accumulation and γ‐secretase inhibition of soluble and insoluble Aβ in a transgenic mouse model of amyloid deposition

2013 · Joanna Parkinson, Bart Ploeger, et al. · Pharmacology Research & Perspectives · 9

Characterization of the Effect of a Novel γ-secretase Modulator on Aβ: A Clinically Translatable Model

2014 · Erik Portelius, Paulina Appelkvist, et al. · Current Pharmaceutical Design · 8

Safety, Tolerability, and Pharmacokinetics of Single Doses of Exidavnemab (BAN0805), an Anti‐α‐Synuclein Antibody, in Healthy Western, Caucasian, Japanese, and Han Chinese Adults

2024 · Emma Boström, Sagar S. Bachhav, et al. · The Journal of Clinical Pharmacology · 7

P3‐011: Biochemical characterization of the TG2576 mouse model: Age‐dependent levels of Amyloid‐beta species and other APP processing fragments in plasma and brain

2011 · Paulina Appelkvist, Susanne Fabre, et al. · Alzheimer s & Dementia · 1

P1‐241: In vivo reduction of beta‐amyloid peptides in the brain of Tg2576 mice after oral administration of a novel BACE1 inhibitor

2012 · Susanna Eketjäll, Juliette Jansson, et al. · Alzheimer s & Dementia

Works count: 12

Citation count: 265

H-index: 8

I10-index: 7