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Chinyere E. Okpara
Observed names:
C. E. Okpara,
C.E. Okpara,
C.J. Okpara,
Chinyere E Okpara,
Chinyere Okpara
Institution:
Eisai (United Kingdom)
Observed institutions:
University of Liverpool,
NYU Langone Health,
Eisai (Germany),
Eisai (United Kingdom),
Eisai (United States),
NYU Grossman Long Island School of Medicine,
Eisai (Japan),
New York University
show all 8
ORCID:
0000-0002-5621-9138
Observed ORCID:
0000-0002-5621-9138
OpenAlex ID:
A5014514185
Lenvatinib Plus Pembrolizumab Versus Sunitinib in First-Line Treatment of Advanced Renal Cell Carcinoma: Final Prespecified Overall Survival Analysis of CLEAR, a Phase III Study
2024
·
Robert J. Motzer
, Camillo Porta
, et al.
·
Journal of Clinical Oncology
·
204
Lenvatinib plus pembrolizumab in patients with either treatment-naive or previously treated metastatic renal cell carcinoma (Study 111/KEYNOTE-146): a phase 1b/2 study
2021
·
Chung-Han Lee
, Amishi Yogesh Shah
, et al.
·
The Lancet Oncology
·
195
Lenvatinib Plus Pembrolizumab in Previously Treated Advanced Endometrial Cancer: Updated Efficacy and Safety From the Randomized Phase III Study 309/KEYNOTE-775
2023
·
Vicky Makker
, Nicoletta Colombo
, et al.
·
Journal of Clinical Oncology
·
173
PDF
Lenvatinib with etoposide plus ifosfamide in patients with refractory or relapsed osteosarcoma (ITCC-050): a multicentre, open-label, multicohort, phase 1/2 study
2021
·
Nathalie Gaspar
, Rajkumar Venkatramani
, et al.
·
The Lancet Oncology
·
91
First-Line Lenvatinib Plus Pembrolizumab Versus Chemotherapy for Advanced Endometrial Cancer: A Randomized, Open-Label, Phase III Trial
2024
·
Christian Marth
, Richard G. Moore
, et al.
·
Journal of Clinical Oncology
·
77
Lenvatinib dose, efficacy, and safety in the treatment of multiple malignancies
2022
·
Robert J. Motzer
, Matthew H. Taylor
, et al.
·
Expert Review of Anticancer Therapy
·
71
Phase I/II study of single-agent lenvatinib in children and adolescents with refractory or relapsed solid malignancies and young adults with osteosarcoma (ITCC-050)☆
2021
·
N. Gaspar
, Q. Campbell-Hewson
, et al.
·
ESMO Open
·
63
PDF
Pembrolizumab With or Without Lenvatinib for First-Line Metastatic NSCLC With Programmed Cell Death-Ligand 1 Tumor Proportion Score of at least 1% (LEAP-007): A Randomized, Double-Blind, Phase 3 Trial
2023
·
James Chih-Hsin Yang
, Baohui Han
, et al.
·
Journal of Thoracic Oncology
·
61
PDF
Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma brucei
2020
·
Ali H Alghamdi
, Jane C Munday
, et al.
·
eLife
·
48
Phase 3 CLEAR study in patients with advanced renal cell carcinoma: outcomes in subgroups for the lenvatinib-plus-pembrolizumab and sunitinib arms
2023
·
Viktor Grünwald
, Thomas Powles
, et al.
·
Frontiers in Oncology
·
44
PDF
Final prespecified overall survival (OS) analysis of CLEAR: 4-year follow-up of lenvatinib plus pembrolizumab (L+P) vs sunitinib (S) in patients (pts) with advanced renal cell carcinoma (aRCC).
2023
·
Robert J. Motzer
, Camillo Porta
, et al.
·
Journal of Clinical Oncology
·
44
LEAP-008: Lenvatinib Plus Pembrolizumab for Metastatic NSCLC That Has Progressed After an Anti–Programmed Cell Death Protein 1 or Anti–Programmed Cell Death Ligand 1 Plus Platinum Chemotherapy
2025
·
Natasha B. Leighl
, Luis Paz-Ares
, et al.
·
Journal of Thoracic Oncology
·
28
PDF
Lenvatinib Plus Ifosfamide and Etoposide in Children and Young Adults With Relapsed Osteosarcoma
2024
·
Nathalie Gaspar
, Giun-Yi Hung
, et al.
·
JAMA Oncology
·
27
Lenvatinib plus pembrolizumab for patients with previously treated advanced ovarian cancer: Results from the phase 2 multicohort LEAP-005 study
2024
·
Antonio González-Martín
, Hyun Cheol Chung
, et al.
·
Gynecologic Oncology
·
27
PDF
Pembrolizumab with or Without Lenvatinib as First-line Therapy for Patients with Advanced Urothelial Carcinoma (LEAP-011): A Phase 3, Randomized, Double-Blind Trial
2023
·
Nobuaki Matsubara
, Ronald de Wit
, et al.
·
European Urology
·
27
PDF
Biomarker analyses from the phase III randomized CLEAR trial: lenvatinib plus pembrolizumab versus sunitinib in advanced renal cell carcinoma
2024
·
R.J. Motzer
, C. Porta
, et al.
·
Annals of Oncology
·
26
PDF
Clinical outcomes by baseline metastases in patients with renal cell carcinoma treated with lenvatinib plus pembrolizumab versus sunitinib: Post hoc analysis of the CLEAR trial
2024
·
Viktor Grünwald
, Rana R. McKay
, et al.
·
International Journal of Cancer
·
22
PDF
Paediatric Strategy Forum for medicinal product development of multi-targeted kinase inhibitors in bone sarcomas
2022
·
Andrew DJ. Pearson
, Nathalie Gaspar
, et al.
·
European Journal of Cancer
·
22
PDF
120O Pembrolizumab (Pembro) with or without lenvatinib (Lenva) in first-line metastatic NSCLC with PD-L1 TPS ≥1% (LEAP-007): A phase III, randomized, double-blind study
2021
·
J.C-H. Yang
, A. Luft
, et al.
·
Annals of Oncology
·
20
Characterization and Management of Adverse Reactions in Patients With Advanced Endometrial Cancer Receiving Lenvatinib Plus Pembrolizumab
2023
·
Nicoletta Colombo
, Domenica Lorusso
, et al.
·
The Oncologist
·
16
PDF
Lenvatinib plus pembrolizumab for patients with previously treated, advanced, triple‐negative breast cancer: Results from the triple‐negative breast cancer cohort of the phase 2 LEAP‐005 Study
2024
·
Hyun Cheol Chung
, Esma Saada‐Bouzid
, et al.
·
Cancer
·
15
PDF
Lenvatinib Plus Pembrolizumab, Pemetrexed, and a Platinum as First-Line Therapy for Metastatic Nonsquamous NSCLC: Phase 3 LEAP-006 Study
2025
·
Roy S. Herbst
, Byoung Chul Cho
, et al.
·
Journal of Thoracic Oncology
·
14
PDF
Randomized, double-blind, phase III LEAP-003 study of first-line lenvatinib plus pembrolizumab versus placebo plus pembrolizumab for unresectable or metastatic melanoma
2025
·
A. Arance
, M.-A. Berciano-Guerrero
, et al.
·
Annals of Oncology
·
11
Biomarker analyses in patients with advanced renal cell carcinoma (aRCC) from the phase 3 CLEAR trial.
2024
·
Robert J. Motzer
, Camillo Porta
, et al.
·
Journal of Clinical Oncology
·
10
65O Phase III LEAP-008 study of lenvatinib plus pembrolizumab versus docetaxel for metastatic non-small cell lung cancer (NSCLC) that progressed on a PD-(L)1 inhibitor and platinum-containing chemotherapy
2023
·
N. Leighl
, L. Paz-Ares
, et al.
·
Immuno-Oncology Technology
·
10
PDF
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Works count:
105
Citation count:
1,462
H-index:
19
I10-index:
25
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