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Shuso Takeda

Identification of cytochrome P450 enzymes responsible for metabolism of cannabidiol by human liver microsomes
2011 · Rongrong Jiang, Satoshi Yamaori, et al. · Life Sciences · 339
Cannabidiolic Acid as a Selective Cyclooxygenase-2 Inhibitory Component in Cannabis
2008 · Shuso Takeda, Koichiro Misawa, et al. · Drug Metabolism and Disposition · 151
Cannabidiolic acid, a major cannabinoid in fiber-type cannabis, is an inhibitor of MDA-MB-231 breast cancer cell migration
2012 · Shuso Takeda, Shunsuke Okajima, et al. · Toxicology Letters · 108
Modulation of UDP-Glucuronosyltransferase Function by Cytochrome P450: Evidence for the Alteration of UGT2B7-Catalyzed Glucuronidation of Morphine by CYP3A4
2004 · Shuso Takeda, Yuji Ishii, et al. · Molecular Pharmacology · 75
Inhibition of Udp-glucuronosyltransferase 2b7-catalyzed Morphine Glucuronidation by Ketoconazole: Dual Mechanisms Involving a Novel Noncompetitive Mode
2006 · Shuso Takeda, Yurie Kitajima, et al. · Drug Metabolism and Disposition · 72
Δ9-Tetrahydrocannabinol Disrupts Estrogen-Signaling through Up-Regulation of Estrogen Receptor β (ERβ)
2013 · Shuso Takeda, Kazutaka Yoshida, et al. · Chemical Research in Toxicology · 65
Modulation of UDP-glucuronosyltransferase activity by protein-protein association
2009 · Yuji Ishii, Shuso Takeda, et al. · Drug Metabolism Reviews · 58
Interaction of Cytochrome P450 3A4 and UDP-Glucuronosyltransferase 2B7: Evidence for Protein-Protein Association and Possible Involvement of CYP3A4 J-Helix in the Interaction
2009 · Shuso Takeda, Yuji Ishii, et al. · Molecular Pharmacology · 51
Protein-Protein Interactions between Rat Hepatic Cytochromes P450 (P450s) and UDP-Glucuronosyltransferases (UGTs): Evidence for the Functionally Active UGT in P450-UGT Complex
2007 · Yuji Ishii, Megumi Iwanaga, et al. · Drug Metabolism and Pharmacokinetics · 50
Down-regulation of cyclooxygenase-2 (COX-2) by cannabidiolic acid in human breast cancer cells
2014 · Shuso Takeda, Hiroyuki Okazaki, et al. · The Journal of Toxicological Sciences · 49
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Cannabidiol-2′,6′-Dimethyl Ether, a Cannabidiol Derivative, Is a Highly Potent and Selective 15-Lipoxygenase Inhibitor
2009 · Shuso Takeda, Noriyuki Usami, et al. · Drug Metabolism and Disposition · 46
Cadmium-induced malignant transformation of rat liver cells: Potential key role and regulatory mechanism of altered apolipoprotein E expression in enhanced invasiveness
2017 · Masayo Suzuki, Shuso Takeda, et al. · Toxicology · 45
Δ9-Tetrahydrocannabinol enhances MCF-7 cell proliferation via cannabinoid receptor-independent signaling
2008 · Shuso Takeda, Satoshi Yamaori, et al. · Toxicology · 45
Cannabidiol induces expression of human cytochrome P450 1A1 that is possibly mediated through aryl hydrocarbon receptor signaling in HepG2 cells
2015 · Satoshi Yamaori, Yuka Kinugasa, et al. · Life Sciences · 42
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Modulation of Δ9-tetrahydrocannabinol-induced MCF-7 breast cancer cell growth by cyclooxygenase and aromatase
2009 · Shuso Takeda, Ikuo Yamamoto, et al. · Toxicology · 42
Δ9-THC modulation of fatty acid 2-hydroxylase (FA2H) gene expression: Possible involvement of induced levels of PPARα in MDA-MB-231 breast cancer cells
2014 · Shuso Takeda, Eriko Ikeda, et al. · Toxicology · 40
Alteration of the Function of the UDP-Glucuronosyltransferase 1A Subfamily by Cytochrome P450 3A4: Different Susceptibility for UGT Isoforms and UGT1A1/7 Variants
2013 · Yuji Ishii, Hiroki Koba, et al. · Drug Metabolism and Disposition · 40
(−)-Xanthatin Selectively Induces GADD45γ and Stimulates Caspase-Independent Cell Death in Human Breast Cancer MDA-MB-231 Cells
2011 · Shuso Takeda, Kazumasa Matsuo, et al. · Chemical Research in Toxicology · 38
Modulation of UDP-Glucuronosyltransferase 2B7 Function by Cytochrome P450s in Vitro: Differential Effects of CYP1A2, CYP2C9 and CYP3A4
2005 · Shuso Takeda, Yuji Ishii, et al. · Biological and Pharmaceutical Bulletin · 38
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Repeated Exposure to 4-Methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene (MBP), an Active Metabolite of Bisphenol A, Aggressively Stimulates Breast Cancer Cell Growth in an Estrogen Receptor β (ERβ)–Dependent Manner
2018 · Masayo Hirao-Suzuki, Shuso Takeda, et al. · Molecular Pharmacology · 36
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2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced change in intestinal function and pathology: evidence for the involvement of arylhydrocarbon receptor-mediated alteration of glucose transportation
2004 · Takumi Ishida, Shoko Kan-o, et al. · Toxicology and Applied Pharmacology · 35
Suppression of fetal testicular cytochrome P450 17 by maternal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin: A mechanism involving an initial effect on gonadotropin synthesis in the pituitary
2007 · Junko Taketoh, Junpei Mutoh, et al. · Life Sciences · 33
Cadmium-stimulated invasion of rat liver cells during malignant transformation: Evidence of the involvement of oxidative stress/TET1-sensitive machinery
2020 · Masayo Hirao-Suzuki, Shuso Takeda, et al. · Toxicology · 32
(−)-Xanthatin up-regulation of the GADD45γ tumor suppressor gene in MDA-MB-231 breast cancer cells: Role of topoisomerase IIα inhibition and reactive oxygen species
2013 · Shuso Takeda, Momoko Noguchi, et al. · Toxicology · 29
Metalloestrogenic effects of cadmium are absent in long-term estrogen-deprived MCF-7 cells: Evidence for the involvement of constitutively activated estrogen receptor α and very low expression of G protein-coupled estrogen receptor 1
2019 · Masayo Hirao-Suzuki, Shuso Takeda, et al. · Toxicology Letters · 28
Works count: 85
Citation count: 2,080
H-index: 26
I10-index: 47
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