Get started
Author

Brian D. Koh

Observed names: B Koh, B. D. Koh, Brian D Koh, Brian Koh
Observed institutions: Merck & Co., Inc., Rahway, NJ, USA (United States), Mayo Clinic, Harvard University, Johns Hopkins University, Yale University, Gilead Sciences (United States)
ORCID: 0009-0009-7825-6042
Observed ORCID: 0009-0009-7825-6042
OpenAlex ID: A5014871015
The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IκB kinase
2001 · Benjamin H.B. Kwok, Brian Koh, et al. · Chemistry & Biology · 515
PDF
Dual mTORC1/mTORC2 inhibition diminishes Akt activation and induces Puma-dependent apoptosis in lymphoid malignancies
2011 · Mamta Gupta, Andrea E. Wahner Hendrickson, et al. · Blood · 103
Idelalisib is effective in patients with high-risk follicular lymphoma and early relapse after initial chemoimmunotherapy
2017 · Ajay K. Gopal, Brad S. Kahl, et al. · Blood · 79
CHK1 and WEE1 inhibition combine synergistically to enhance therapeutic efficacy in acute myeloid leukemia ex vivo
2013 · L. Chaudhuri, N. D. Vincelette, et al. · Haematologica · 78
PDF
Poly(ADP-ribose) Polymerase Inhibitors Sensitize Cancer Cells to Death Receptor-mediated Apoptosis by Enhancing Death Receptor Expression
2014 · X.Wei Meng, Brian D. Koh, et al. · Journal of Biological Chemistry · 61
Effects of Selective Checkpoint Kinase 1 Inhibition on Cytarabine Cytotoxicity in Acute Myelogenous Leukemia Cells In Vitro
2012 · Erin L. Schenk, Brian D. Koh, et al. · Clinical Cancer Research · 56
Total Synthesis of Luminacin D
2002 · J. Brad Shotwell, Evan S. Krygowski, et al. · Organic Letters · 45
Histone deacetylase inhibitors interrupt HSP90•RASGRP1 and HSP90•CRAF interactions to upregulate BIM and circumvent drug resistance in lymphoma cells
2016 · H Ding, K L Peterson, et al. · Leukemia · 39
Phase 1 dose-escalation study of momelotinib, a Janus kinase 1/2 inhibitor, combined with gemcitabine and nab-paclitaxel in patients with previously untreated metastatic pancreatic ductal adenocarcinoma
2018 · Kimmie Ng, Andrew Hendifar, et al. · Investigational New Drugs · 37
PDF
Phase Ib Study of the BET Inhibitor GS-5829 as Monotherapy and Combined with Enzalutamide in Patients with Metastatic Castration-Resistant Prostate Cancer
2022 · Rahul Aggarwal, Alexander N. Starodub, et al. · Clinical Cancer Research · 27
Poly (ADP-Ribose) Polymerase Inhibitor Hypersensitivity in Aggressive Myeloproliferative Neoplasms
2016 · Keith W. Pratz, Brian D. Koh, et al. · Clinical Cancer Research · 25
Chemical Genetics
2002 · Brian Koh, Craig M Crews · Neuron · 15
PDF
Inhibitors of NF-κB signaling: design and synthesis of a biotinylated isopanepoxydone affinity reagent
2002 · J.Brad Shotwell, Brian Koh, et al. · Bioorganic & Medicinal Chemistry Letters · 14
Characterization of a Novel Mammalian Phosphatase Having Sequence Similarity to Schizosaccharomyces pombe PHO2 and Saccharomyces cerevisiae PHO13
2002 · MacKevin I. Ndubuisil, Benjamin H. B. Kwok, et al. · Biochemistry · 10
Activity of Idelalisib in High-Risk Follicular Lymphoma with Early Relapse Following Front Line Immunochemotherapy
2015 · Ajay K Gopal, Brad S Kahl, et al. · Blood · 9
CDK2-Mediated Upregulation of TNFα as a Mechanism of Selective Cytotoxicity in Acute Leukemia
2021 · Husheng Ding, Nicole D. Vincelette, et al. · Cancer Research · 7
Genetic and Epigenetic Defects in DNA Repair Lead to Synthetic Lethality of Poly (ADP-Ribose) Polymerase (PARP) Inhibitors in Aggressive Myeloproliferative Disorders
2011 · Michael A McDevitt, Brian D Koh, et al. · Blood · 5
Central retinal vein occlusion after plateletpheresis
2016 · Gavin W. Roddy, Justin D. Kreuter, et al. · Transfusion · 4
Letter to the Editor
1996 · Maryellen Ruvolo, Brian D. Koh · Molecular Phylogenetics and Evolution · 1
Data from CDK2-Mediated Upregulation of TNFα as a Mechanism of Selective Cytotoxicity in Acute Leukemia
2023 · Husheng Ding, Nicole D. Vincelette, et al.
Supplementary Data from Phase Ib Study of the BET Inhibitor GS-5829 as Monotherapy and Combined with Enzalutamide in Patients with Metastatic Castration-Resistant Prostate Cancer
2023 · Rahul Aggarwal, Alexander N. Starodub, et al.
Supplementary Data from CDK2-Mediated Upregulation of TNFα as a Mechanism of Selective Cytotoxicity in Acute Leukemia
2023 · Husheng Ding, Nicole D. Vincelette, et al.
PDF
Supplementary Tables 1 - 2, Figure 1 from Effects of Selective Checkpoint Kinase 1 Inhibition on Cytarabine Cytotoxicity in Acute Myelogenous Leukemia Cells In Vitro
2023 · Erin L. Schenk, Brian D. Koh, et al.
Supplemental Table and Figures from Poly (ADP-Ribose) Polymerase Inhibitor Hypersensitivity in Aggressive Myeloproliferative Neoplasms
2023 · Keith W. Pratz, Brian D. Koh, et al.
Supplementary Data from Phase Ib Study of the BET Inhibitor GS-5829 as Monotherapy and Combined with Enzalutamide in Patients with Metastatic Castration-Resistant Prostate Cancer
2023 · Rahul Aggarwal, Alexander N. Starodub, et al.
Works count: 38
Citation count: 1,130
H-index: 13
I10-index: 14
Year
Topic
Type