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Václav Šeda

B‐cell receptor signalling and its crosstalk with other pathways in normal and malignant cells
2014 · Vaclav Seda, Marek Mraz · European Journal Of Haematology · 205
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Ibrutinib inhibits CD20 upregulation on CLL B cells mediated by the CXCR4/SDF-1 axis
2016 · Gabriela Pavlasova, Marek Borsky, et al. · Blood · 110
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MicroRNA miR-34a downregulates FOXP1 during DNA damage response to limit BCR signalling in chronic lymphocytic leukaemia B cells
2018 · Katerina Cerna, Jan Oppelt, et al. · Leukemia · 64
miR-150 downregulation contributes to the high-grade transformation of follicular lymphoma by upregulating FOXP1 levels
2018 · Katerina Musilova, Jan Devan, et al. · Blood · 63
miR-29 modulates CD40 signaling in chronic lymphocytic leukemia by targeting TRAF4: an axis affected by BCR inhibitors
2021 · Sonali Sharma, Gabriela Mladonicka Pavlasova, et al. · Blood · 62
Rituximab primarily targets an intra-clonal BCR signaling proficient CLL subpopulation characterized by high CD20 levels
2018 · Gabriela Pavlasova, Marek Borsky, et al. · Leukemia · 36
FoxO1-GAB1 axis regulates homing capacity and tonic AKT activity in chronic lymphocytic leukemia
2021 · Vaclav Seda, Eva Vojackova, et al. · Blood · 33
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Novel CHK1 inhibitor MU380 exhibits significant single-agent activity in TP53-mutated chronic lymphocytic leukemia cells
2019 · Miroslav Boudny, Jana Zemanova, et al. · Haematologica · 26
IL4-STAT6 signaling induces CD20 in chronic lymphocytic leukemia and this axis is repressed by PI3Kδ inhibitor idelalisib
2021 · Veronika Sandova, Gabriela Mladonicka Pavlasova, et al. · Haematologica · 22
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TGF-β1 signaling plays a dominant role in the crosstalk between TGF-β1 and the aryl hydrocarbon receptor ligand in prostate epithelial cells
2012 · Andrea Staršíchová, Eva Hrubá, et al. · Cellular Signalling · 19
FoxO1/Rictor axis induces a nongenetic adaptation to ibrutinib via Akt activation in chronic lymphocytic leukemia
2024 · Laura Ondrisova, Vaclav Seda, et al. · Journal of Clinical Investigation · 16
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Stromal cells engineered to express T cell factors induce robust CLL cell proliferation in vitro and in PDX co-transplantations allowing the identification of RAF inhibitors as anti-proliferative drugs
2024 · Eva Hoferkova, Vaclav Seda, et al. · Leukemia · 8
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Repression of miR-29 via MYC leads to increased CD40 signaling in transformed follicular lymphoma
2026 · Daniel Filip, Katerina Litzmanova, et al. · Leukemia · 1
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Microenvironmental Interactions up-Regulate CD20 Expression in CLL B Cells through the CXCR4/SDF-1 Axis: Implications for CD20-Targeting Antibodies and the Use of BCR-Inhibitors in Combination
2015 · Gabriela Pavlasova, Vaclav Seda, et al. · Blood · 1
Gene expression analysis after BTK and PI3Kδ inhibitor treatment in chronic lymphocytic leukemia identifies cell‐surface CXCR4 as a synergistic target for combinatorial therapy
2026 · Gabriela Mladonicka Pavlasova, Veronika Sandova, et al. · HemaSphere
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81 | REPRESSION OF miR‐29 VIA MYC LEADS TO INCREASED CD40 SIGNALING IN TRANSFORMED FOLLICULAR LYMPHOMA (FL) AND UNFAVOURABLE PROGNOSIS IN FL
2025 · D. Filip, K. Litzmanova, et al. · Hematological Oncology
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Molecular Mechanism of Non-genetic Adaptation to Btk Inhibitor Therapy in Cll
2024 · Ondrišová Laura, Šeda Václav, et al. · Veřejné služby Informačního systému (Masarykiana Brunensis Universitas)
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Stromal Cells Engineered to Express T Cell Factors Induce Robust Cll Cell Proliferation in Vitro and in Pdx Cotransplantations Allowing the Identification of Anti-proliferative Drugs
2024 · Hoferková Eva, Filip Daniel, et al. · Veřejné služby Informačního systému (Masarykiana Brunensis Universitas)
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S142: Foxo1-rictor Axis Induces Adaptive Increase in Akt Activity During Bcr Inhibitor Therapy in Cll: Implications for Combination Therapy
2023 · Laura Ondrisova, Vaclav Seda, et al. · HemaSphere
Foxo1‐rictor Axis Induces Akt Phosphorylation During Cll Cell Adaptation to Bcr Inhibitors: Implications for Combinatorial Therapy
2023 · L. Ondrisova, V. Seda, et al. · Hematological Oncology
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Nekódující RNA v biologii maligních B lymfocytů.
2023 · Faria Zeni Pedro, Filip Daniel, et al. · Veřejné služby Informačního systému (Masarykiana Brunensis Universitas)
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The role of long non-coding RNAs in BCR-mediated CLL activation.
2023 · Faria Zeni Pedro, Medková Michaela, et al. · Veřejné služby Informačního systému (Masarykiana Brunensis Universitas)
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Foxo1-Rictor axis mediates adaptive increase in Akt activity and cell survival during BCR inhibitor therapy in chronic lymphocytic leukemia.
2023 · Hlaváč Kryštof, Ondrišová Laura, et al. · Veřejné služby Informačního systému (Masarykiana Brunensis Universitas)
Transkripční faktor FoxO1 v adaptaci chronické lymfocytární leukémie na cílenou léčbu.
2023 · Ondrišová Laura, Šeda Václav, et al. · Veřejné služby Informačního systému (Masarykiana Brunensis Universitas)
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Molecular response of chronic lymphocytic leukemia cells to targeted therapy.
2023 · Hlaváč Kryštof, Ondrišová Laura, et al. · Veřejné služby Informačního systému (Masarykiana Brunensis Universitas)
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Works count: 63
Citation count: 666
H-index: 11
I10-index: 11
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