Author

Najumuddin

Institution: Hamdard University

Observed institutions: Quaid-i-Azam University, Hamdard University

ORCID: 0000-0002-8324-6019

Observed ORCID: 0000-0002-8324-6019

OpenAlex ID: A5014924617

Antagonistic role of Klotho-derived peptides dynamics in the pancreatic cancer treatment through obstructing WNT-1 and Frizzled binding

2018 · Muhammad Fakhar, Najumuddin, et al. · Biophysical Chemistry · 22

Novel Variants in MPV17, PRX, GJB1, and SACS Cause Charcot–Marie–Tooth and Spastic Ataxia of Charlevoix–Saguenay Type Diseases

2023 · Qaiser Zaman, Muhammad Abbas Khan, et al. · Genes · 16

Whole exome sequencing identified five novel variants in CNTN2, CARS2, ARSA, and CLCN4 leading to epilepsy in consanguineous families

2023 · Angham Abdulrhman Abdulkareem, Qaiser Zaman, et al. · Frontiers in Genetics · 10

Variants in EFCAB7 underlie nonsyndromic postaxial polydactyly

2023 · Muhammad Bilal, Hammal Khan, et al. · European Journal of Human Genetics · 9

Interactive structural analysis of βTrCP1 and PER2 phosphoswitch binding through dynamics simulation assay

2018 · Najumuddin, Muhammad Fakhar, et al. · Archives of Biochemistry and Biophysics · 7

Structural basis of Klotho binding to VEGFR2 and TRPC1 and repurposing calcium channel blockers as TRPC1 antagonists for the treatment of age-related cardiac hypertrophy

2022 · Muhammad Fakhar, Najumuddin, et al. · Archives of Biochemistry and Biophysics · 6

Phosphorylation-dependent activity-based conformational changes in P21-activated kinase family members and screening of novel ATP competitive inhibitors

2019 · Mehreen Gul, Muhammad Fakhar, et al. · PLoS ONE · 6

Sequence variants in the BTD underlying biotinidase deficiency in families of Pakistani origin

2023 · Tariq Moatter, Sibtain Ahmed, et al. · The Journal of Gene Medicine · 5

Case report: A novel de novo loss of function variant in the DNA-binding domain of TBX2 causes severe osteochondrodysplasia

2023 · Misbahuddin M. Rafeeq, Hussam Aly Sayed Murad, et al. · Frontiers in Genetics · 5

Patuletin from Tagetes patula: an Inhibitor of MMP-2 and MMP-9 in Collagen-Induced Arthritis Rat Model and Virtual Screening Analysis

2023 · Zaid Abdul Razzak, Syed Taj Afzal, et al. · Revista Brasileira de Farmacognosia · 3

NAV3 Missense Variant in a Homozygous State: Strengthening Links to Neurodevelopmental Disorder

2025 · Muhammad Umair, Anwar Ullah, et al. · Current Medicinal Chemistry · 2

Metabolism configures immune response across multi-systems: Lessons from COVID-19

2023 · Tinku Gupta, Najumuddin, et al. · Advances in Biological Regulation · 2

Evidence for NAD+-dependent histone dynamics and tunneling associated conformational transitions in circadian deacetylase SIRT1

2020 · Najumuddin, Muhammad Fakhar, et al. · Journal of Molecular Graphics and Modelling · 2

Site-directed mutagenesis and semi-rational design to enhance chitinolytic activity of bacterial exochitinase

2026 · Mati Ullah, Jianda Han, et al. · Microbial Cell Factories · 1

Two novel homozygous variants of ATP6V0A2 and ALDH18A1 lead to autosomal recessive cutis laxa type 2 and 3 in two Pakistani families

2023 · Qaiser Zaman, Aiman Iftikhar, et al. · The Journal of Gene Medicine · 1

The genetic spectrum of achromatopsia in consanguineous families: insights from Whole exome sequencing across 15 affected individuals

2026 · Sonehra, Qaiser Zaman, et al. · Ophthalmic Genetics

Microbiome and Circadian Rhythms: Implications for Sleep, Aging, and Therapeutic Strategies

2024 · Najumuddin, Ihsan Ullah, et al. · Springer eBooks

Works count: 17

Citation count: 97

H-index: 6

I10-index: 3