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Laura P. van Lieshout

Observed names: Laura P van Lieshout, Laura P. Van Lieshout, Laura Van Lieshout, Laura van Lieshout, Van Lieshout, Laura
ORCID: 0000-0001-7977-3978
Observed ORCID: 0000-0001-7977-3978
OpenAlex ID: A5015009070
A Novel Triple-Mutant AAV6 Capsid Induces Rapid and Potent Transgene Expression in the Muscle and Respiratory Tract of Mice
2018 · Laura P. van Lieshout, Jakob M. Domm, et al. · Molecular Therapy — Methods & Clinical Development · 93
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A lung tropic AAV vector improves survival in a mouse model of surfactant B deficiency
2020 · Martin H. Kang, Laura P. van Lieshout, et al. · Nature Communications · 88
AAV vector distribution in the mouse respiratory tract following four different methods of administration
2017 · Lisa A. Santry, Joelle C. Ingrao, et al. · BMC Biotechnology · 62
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Intramuscular Adeno-Associated Virus–Mediated Expression of Monoclonal Antibodies Provides 100% Protection Against Ebola Virus Infection in Mice
2017 · Laura P van Lieshout, Geoff Soule, et al. · The Journal of Infectious Diseases · 48
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AAV-Mediated Gene Delivery to the Lung
2019 · Laura P. van Lieshout, Jakob M. Domm, et al. · Methods in molecular biology · 33
A novel dual-plasmid platform provides scalable transfection yielding improved productivity and packaging across multiple AAV serotypes and genomes
2023 · Laura P. van Lieshout, Miranda Rubin, et al. · Molecular Therapy — Methods & Clinical Development · 29
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AAV Vectored Immunoprophylaxis for Filovirus Infections
2020 · Amira D. Rghei, Laura P. van Lieshout, et al. · Tropical Medicine and Infectious Disease · 17
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Adeno-associated virus mediated expression of monoclonal antibody MR191 protects mice against Marburg virus and provides long-term expression in sheep
2022 · Amira D. Rghei, Laura P. van Lieshout, et al. · Gene Therapy · 16
AAV-monoclonal antibody expression protects mice from Ebola virus without impeding the endogenous antibody response to heterologous challenge
2022 · Laura P. van Lieshout, Amira D. Rghei, et al. · Molecular Therapy — Methods & Clinical Development · 15
AAV-mediated delivery of actoxumab and bezlotoxumab results in serum and mucosal antibody concentrations that provide protection from C. difficile toxin challenge
2021 · Matthew M. Guilleman, Brenna A. Y. Stevens, et al. · Gene Therapy · 14
Engineered AAV8 capsid acquires heparin and AVB sepharose binding capacity but has altered in vivo transduction efficiency
2020 · Laura P. van Lieshout, Ashley A. Stegelmeier, et al. · Gene Therapy · 14
An Improved Helper Plasmid Containing Deletions Within the E4 and E2a Genes Results in Increased Adeno-Associated Virus Productivity
2024 · Laura van Lieshout, Stacy Ota, et al. · Human Gene Therapy · 12
The U3 and Env Proteins of Jaagsiekte Sheep Retrovirus and Enzootic Nasal Tumor Virus Both Contribute to Tissue Tropism
2019 · María C. Rosales Gerpe, Laura P. van Lieshout, et al. · Viruses · 12
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A promoterless AAV6.2FF-based lung gene editing platform for the correction of surfactant protein B deficiency
2023 · Sylvia P. Thomas, Jakob M. Domm, et al. · Molecular Therapy · 11
Efficient Transduction of Alveolar Type 2 Cells with Adeno-associated Virus for the Study of Lung Regeneration
2021 · Tara N. Rindler, Kari M. Brown, et al. · American Journal of Respiratory Cell and Molecular Biology · 11
Optimized Pre-Clinical Grade Production of Two Novel Lentiviral Vector Pseudotypes for Lung Gene Delivery
2020 · María C. Rosales Gerpe, Laura P. van Lieshout, et al. · Human Gene Therapy · 10
Safety and Tolerability of the Adeno-Associated Virus Vector, AAV6.2FF, Expressing a Monoclonal Antibody in Murine and Ovine Animal Models
2021 · Amira D. Rghei, Laura P. van Lieshout, et al. · Biomedicines · 9
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Antibody-based protection against respiratory syncytial virus in mice and their offspring through vectored immunoprophylaxis
2023 · Amira D. Rghei, Jacob G. E. Yates, et al. · Gene Therapy · 7
Natural variations in AAVHSC16 significantly reduce liver tropism and maintain broad distribution to periphery and CNS
2022 · Laura J. Smith, Lindsay A. Schulman, et al. · Molecular Therapy — Methods & Clinical Development · 5
AAV Vectors Pseudotyped with Capsids from Porcine and Bovine Species Mediate In Vitro and In Vivo Gene Delivery
2023 · Darrick L. Yu, Laura P. van Lieshout, et al. · Viruses · 4
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Structural analysis of recombinant AAV vector genomes at single-molecule resolution
2026 · David Rouleau, Dimpal Lata, et al. · PLoS ONE · 1
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An engineered helper plasmid generates differential E4orf6 and L4-22/33K gene expression increasing AAV vector production
2026 · Laura van Lieshout, Katrina Costa-Grant, et al. · Gene Therapy
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rAAV_Genome_Structural_Breakpoint_Analyzer
2026 · Rouleau, David, Lata, Dimpal, et al. · Zenodo (CERN European Organization for Nuclear Research)
rAAV_Structural_Variant_Classifier
2026 · Rouleau, David, Lata, Dimpal, et al. · Zenodo (CERN European Organization for Nuclear Research)
Vectorized SARS-CoV-2 Human IgG Expression in Mice and Ovine Animal Models Is Feasible and Well Tolerated
2021 · Amira D. Rghei, Laura P. van Lieshout, et al. · Molecular Therapy
Works count: 26
Citation count: 511
H-index: 12
I10-index: 16
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