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Shaharyar M. Khan
Observed names:
Khan, Shaharyar M.,
SHAHARYAR M. KHAN,
Shaharyar Khan,
Shaharyar M Khan
Observed institutions:
University of Kansas,
University of Virginia Health System,
Gencia (United States),
University Hospitals Sussex NHS Foundation Trust,
Rivus Pharmaceuticals, Inc. (United States),
University of Virginia
show all 6
OpenAlex ID:
A5015098516
The Alzheimer's disease mitochondrial cascade hypothesis: Progress and perspectives
2013
·
Russell H. Swerdlow
, Jeffrey M. Burns
, et al.
·
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
·
783
PDF
A “mitochondrial cascade hypothesis” for sporadic Alzheimer's disease
2004
·
Russell H Swerdlow
, Shaharyar M Khan
·
Medical Hypotheses
·
755
The Alzheimer's Disease Mitochondrial Cascade Hypothesis
2010
·
Russell H. Swerdlow
, Jeffrey M. Burns
, et al.
·
Journal of Alzheimer s Disease
·
562
PDF
The Alzheimer's disease mitochondrial cascade hypothesis: An update
2009
·
Russell H. Swerdlow
, Shaharyar M. Khan
·
Experimental Neurology
·
206
DNA extraction procedures meaningfully influence qPCR-based mtDNA copy number determination
2009
·
Wen Guo
, Lan Jiang
, et al.
·
Mitochondrion
·
183
Alzheimer's disease cybrids replicate ?-amyloid abnormalities through cell death pathways
2000
·
Shaharyar M. Khan
, David S. Cassarino
, et al.
·
Annals of Neurology
·
159
The landscape of small-molecule prodrugs
2024
·
Zachary Fralish
, Ashley Chen
, et al.
·
Nature Reviews Drug Discovery
·
151
Oxidative Stress, Mitochondrial Dysfunction, and Stress Signaling in Alzheimers Disease
2006
·
Isaac Onyango
, Shaharyar Khan
·
Current Alzheimer Research
·
123
Mitochondrial Gene Therapy Augments Mitochondrial Physiology in a Parkinson's Disease Cell Model
2009
·
Paula M. Keeney
, Caitlin K. Quigley
, et al.
·
Human Gene Therapy
·
88
Inhibition by R(+) or S(–) pramipexole of caspase activation and cell death induced by methylpyridinium ion or beta amyloid peptide in SH‐SY5Y neuroblastoma
2002
·
Nicole A. Abramova
, David S. Cassarino
, et al.
·
Journal of Neuroscience Research
·
74
Inhibition of ATP synthase reverse activity restores energy homeostasis in mitochondrial pathologies
2023
·
Rebeca Acin‐Perez
, Cristiane Benincá
, et al.
·
The EMBO Journal
·
70
PDF
Mitochondrial Microheteroplasmy and a Theory of Aging and Age-Related Disease
2005
·
Rafal M. Smigrodzki
, Shaharyar M. Khan
·
Rejuvenation Research
·
63
Mitochondrial genomic contribution to mitochondrial dysfunction in Alzheimer's disease
2006
·
Isaac Onyango
, Shaharyar Khan
, et al.
·
Journal of Alzheimer s Disease
·
60
Recombinant human mitochondrial transcription factor A stimulates mitochondrial biogenesis and ATP synthesis, improves motor function after MPTP, reduces oxidative stress and increases survival after endotoxin
2010
·
Ravindar R. Thomas
, Shaharyar M. Khan
, et al.
·
Mitochondrion
·
56
RhTFAM treatment stimulates mitochondrial oxidative metabolism and improves memory in aged mice
2012
·
Ravindar R. Thomas
, Shaharyar M. Khan
, et al.
·
Aging
·
52
Development of Mitochondrial Gene Replacement Therapy
2004
·
Shaharyar M. Khan
, James P. Bennett
·
Journal of Bioenergetics and Biomembranes
·
49
The Begums of Bhopal
2000
·
Shaharyar M. Khan
·
I.B. Tauris & Co Ltd eBooks
·
44
Cell and animal models of mtDNA biology: progress and prospects
2006
·
Shaharyar M. Khan
, Rafal M. Smigrodzki
, et al.
·
American Journal of Physiology-Cell Physiology
·
43
Safety and efficacy of once-daily HU6 versus placebo in people with non-alcoholic fatty liver disease and high BMI: a randomised, double-blind, placebo-controlled, phase 2a trial
2023
·
Mazen Noureddin
, Shaharyar Khan
, et al.
·
The Lancet. Gastroenterology & hepatology
·
42
Effects of single and multiple treatments with L-dihydroxyphenylalanine (L-DOPA) on dopamine receptor-G protein interactions and supersensitive immediate early gene responses in striata of rats after reserpine treatment or with unilateral nigrostriatal le
1999
·
Shaharyar M. Khan
, Trisha S. Smith
, et al.
·
Journal of Neuroscience Research
·
22
Novel Controlled Metabolic Accelerator for Obesity-Related HFpEF
2025
·
Ambarish Pandey
, Gregory D. Lewis
, et al.
·
JAMA Cardiology
·
20
Mitochondrial toxins in models of neurodegenerative diseases. II: elevated zif268 transcription and independent temporal regulation of striatal D1 and D2 receptor mRNAs and D1 and D2 receptor-binding sites in C57BL/6 mice during MPTP treatment
1997
·
Trisha S Smith
, Patricia A Trimmer
, et al.
·
Brain Research
·
20
RNA-seq analyses reveal that cervical spinal cords and anterior motor neurons from amyotrophic lateral sclerosis subjects show reduced expression of mitochondrial DNA-encoded respiratory genes, and rhTFAM may correct this respiratory deficiency
2017
·
Amy C. Ladd
, David G. Brohawn
, et al.
·
Brain Research
·
19
A Novel Controlled Metabolic Accelerator for the Treatment of Obesity-Related Heart Failure with Preserved Ejection Fraction: Rationale and Design of the Phase 2a HuMAIN Trial
2024
·
Dalane W. Kitzman
, Gregory D. Lewis
, et al.
·
European Journal of Heart Failure
·
14
PDF
Alzheimer's disease cybrids replicate β‐amyloid abnormalities through cell death pathways
2000
·
Shaharyar M. Khan
, David S. Cassarino
, et al.
·
Annals of Neurology
·
7
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Works count:
42
Citation count:
3,687
H-index:
20
I10-index:
24
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