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Michael Garton

Observed names: Garton, Michael, Michael J Garton
ORCID: 0000-0002-5829-6532
Observed ORCID: 0000-0002-5829-6532
OpenAlex ID: A5015137044
C2H2 zinc finger proteins greatly expand the human regulatory lexicon
2015 · Hamed S Najafabadi, Sanie Mnaimneh, et al. · Nature Biotechnology · 344
Method to generate highly stable D-amino acid analogs of bioactive helical peptides using a mirror image of the entire PDB
2018 · Michael Garton, Satra Nim, et al. · Proceedings of the National Academy of Sciences · 131
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Shifting landscapes of human MTHFR missense-variant effects
2021 · Jochen Weile, Nishka Kishore, et al. · The American Journal of Human Genetics · 67
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A structural approach reveals how neighbouring C2H2 zinc fingers influence DNA binding specificity
2015 · Michael Garton, Hamed S. Najafabadi, et al. · Nucleic Acids Research · 48
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Strategies to Develop Inhibitors of Motif-Mediated Protein-Protein Interactions as Drug Leads
2016 · Carles Corbi-Verge, Michael Garton, et al. · The Annual Review of Pharmacology and Toxicology · 47
Non-base-contacting residues enable kaleidoscopic evolution of metazoan C2H2 zinc finger DNA binding
2017 · Hamed S. Najafabadi, Michael Garton, et al. · Genome biology · 43
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Systematically testing human HMBS missense variants to reveal mechanism and pathogenic variation
2023 · Warren van Loggerenberg, Shahin Sowlati-Hashjin, et al. · The American Journal of Human Genetics · 31
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The functional landscape of coding variation in the familial hypercholesterolemia gene LDLR
2025 · Daniel R. Tabet, Atina G. Coté, et al. · Science · 30
A Comprehensive Model for the Recognition of Human Telomeres by TRF1
2013 · Michael Garton, Charles Laughton · Journal of Molecular Biology · 21
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Interplay of self-association and conformational flexibility in regulating protein function
2018 · Michael Garton, Stephen S. MacKinnon, et al. · Philosophical Transactions of the Royal Society B Biological Sciences · 19
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Dawn of a New Era for Membrane Protein Design
2022 · Shahin Sowlati-Hashjin, Aanshi Gandhi, et al. · BioDesign Research · 15
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Variational autoencoder for design of synthetic viral vector serotypes
2024 · Suyue Lyu, Shahin Sowlati-Hashjin, et al. · Nature Machine Intelligence · 14
A computational approach for designing D-proteins with non-canonical amino acid optimised binding affinity
2017 · Michael Garton, Maryam Sayadi, et al. · PLoS ONE · 13
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ProteinVAE: Variational AutoEncoder for Translational Protein Design
2023 · Suyue Lyu, Shahin Sowlati-Hashjin, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 11
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Rapid and accurate structure‐based therapeutic peptide design using GPU accelerated thermodynamic integration
2018 · Michael Garton, Carles Corbi‐Verge, et al. · Proteins Structure Function and Bioinformatics · 9
The geometric influence on the Cys2His2 zinc finger domain and functional plasticity
2020 · April L Mueller, Carles Corbi-Verge, et al. · Nucleic Acids Research · 8
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FAST-STEM: A human pluripotent stem cell engineering toolkit for rapid design-build-test-learn development of human cell-based therapeutic devices
2024 · Aaron Rosenstein, Rangarajan Sambathkumar, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 4
What do you most hope we will achieve with mammalian synthetic biology within the next decade?
2025 · Martin Fussenegger, Yvonne Y. Chen, et al. · Cell Systems · 2
A Flexible Transgene Integration ‘Landing-Pad’ Toolkit in Human Induced Pluripotent Stem Cells Enables Facile Cellular Engineering, Gene Zygosity Control, and Parallel Transgene Integration
2023 · Aaron H. Rosenstein, Maria Nguyen, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
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ARCHIVE: An Efficient Open-Ended DNA Recording Device Capable of Multiplex Capture of Pol-II Transcribed Signals
2026 · Aaron H. Rosenstein, Michael Garton · bioRxiv (Cold Spring Harbor Laboratory)
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ϑ-Spiral Discovery Reveals a New Class of Biological Building Block
2024 · Michael Garton · Research Square
FAST-STEM: Synthetic Biology Toolkit for Next Generation Regenerative Medicine
2024 · Aaron H. Rosenstein, Andrew Chai, et al. · SSRN Electronic Journal
Engineering Human Cell-Based Radioresistance to Bolster Astronaut Health on Long-Term Space Missions
2024 · Aaron Rosenstein, Daniel Benko, et al.
Additional file 2: Table S1. of Non-base-contacting residues enable kaleidoscopic evolution of metazoan C2H2 zinc finger DNA binding
2017 · Najafabadi, Hamed, Garton, Michael, et al. · Figshare
Additional file 1: of Non-base-contacting residues enable kaleidoscopic evolution of metazoan C2H2 zinc finger DNA binding
2017 · Najafabadi, Hamed, Garton, Michael, et al. · Figshare
Works count: 29
Citation count: 859
H-index: 13
I10-index: 14
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