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Author

Geoffrey C. Guittard

Observed names: G C Guittard, G. Guittard, Geoff Guittard, Geoffery Guittard, Geoffrey C Guittard, Geoffrey Guittard
Observed institutions: Centre National de la Recherche Scientifique, National Institutes of Health, Inserm, Aix-Marseille Université, Immunité et Cancer, National Cancer Institute, Centre de Recherche en Cancérologie de Marseille, Center for Cancer Research, Institut Paoli-Calmettes
ORCID: 0000-0002-6061-8553
Observed ORCID: 0000-0002-6061-8553
OpenAlex ID: A5015244527
Ionic immune suppression within the tumour microenvironment limits T cell effector function
2016 · Robert Eil, Suman K. Vodnala, et al. · Nature · 706
Cish actively silences TCR signaling in CD8+ T cells to maintain tumor tolerance
2015 · Douglas C. Palmer, Geoffrey C. Guittard, et al. · The Journal of Experimental Medicine · 200
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Vitamin D Controls Tumor Growth and CD8+ T Cell Infiltration in Breast Cancer
2019 · Esma Karkeni, Stéphanie O. Morin, et al. · Frontiers in Immunology · 100
Targeting CISH enhances natural cytotoxicity receptor signaling and reduces NK cell exhaustion to improve solid tumor immunity
2022 · Pierre-Louis Bernard, Rebecca Delconte, et al. · Journal for ImmunoTherapy of Cancer · 85
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Loss of XIST Impairs Human Mammary Stem Cell Differentiation and Increases Tumorigenicity Through Enhancer and Mediator Complex Hyperactivation
2021 · Laia Richart, Mary-Loup Picod-Chedotel, et al. · Cell · 78
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Cutting Edge: Dok-1 and Dok-2 Adaptor Molecules Are Regulated by Phosphatidylinositol 5-Phosphate Production in T Cells
2009 · Geoffrey Guittard, Audrey Gérard, et al. · The Journal of Immunology · 72
B7-DC-Ig Enhances Vaccine Effect by a Novel Mechanism Dependent on PD-1 Expression Level on T Cell Subsets
2012 · Mikayel Mkrtichyan, Yana G Najjar, et al. · The Journal of Immunology · 47
Negative intracellular regulators of T-cell receptor (TCR) signaling as potential antitumor immunotherapy targets
2023 · Vladimir Laletin, Pierre-Louis Bernard, et al. · Journal for ImmunoTherapy of Cancer · 46
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NK Cell Priming From Endogenous Homeostatic Signals Is Modulated by CIS
2020 · Rebecca B. Delconte, Geoffrey Guittard, et al. · Frontiers in Immunology · 46
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A Prime-Pull-Amplify Vaccination Strategy To Maximize Induction of Circulating and Genital-Resident Intraepithelial CD8+ Memory T Cells
2019 · Nicolas Çuburu, Rina Kim, et al. · The Journal of Immunology · 46
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The Cish SH2 domain is essential for PLC-γ1 regulation in TCR stimulated CD8+ T cells
2018 · Geoffrey Guittard, Ana Dios-Esponera, et al. · Scientific Reports · 33
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Absence of both Sos‐1 and Sos‐2 in peripheral CD4+ T cells leads to PI3K pathway activation and defects in migration
2015 · Geoffrey Guittard, Robert L. Kortum, et al. · European Journal of Immunology · 29
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Evidence for a positive role of PtdIns5P in T‐cell signal transduction pathways
2010 · Geoffrey Guittard, Eva Mortier, et al. · FEBS Letters · 27
Dok-4 Is a Novel Negative Regulator of T Cell Activation
2009 · Audrey Gérard, Marguerite Ghiotto, et al. · The Journal of Immunology · 27
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Anti-HVEM mAb therapy improves antitumoral immunity both in vitro and in vivo, in a novel transgenic mouse model expressing human HVEM and BTLA molecules challenged with HVEM expressing tumors
2023 · C. Demerle, L. Gorvel, et al. · Journal for ImmunoTherapy of Cancer · 23
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TP53INP1 deficiency maintains murine B lymphopoiesis in aged bone marrow through redox-controlled IL-7R/STAT5 signaling
2018 · Bochra Zidi, Christelle Vincent-Fabert, et al. · Proceedings of the National Academy of Sciences · 23
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Enhancing natural killer cells proliferation and cytotoxicity using imidazole-based lipid nanoparticles encapsulating interleukin-2 mRNA
2024 · Christophe Delehedde, Ivan Ciganek, et al. · Molecular Therapy — Nucleic Acids · 18
Targeting BTN2A1 Enhances Vγ9Vδ2 T-Cell Effector Functions and Triggers Tumor Cell Pyroptosis
2024 · Anne Charlotte le Floch, Caroline Imbert, et al. · Cancer Immunology Research · 14
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Unexpected Cartilage Phenotype in CD4-Cre-Conditional SOS-Deficient Mice
2017 · Geoffrey Guittard, Devorah L. Gallardo, et al. · Frontiers in Immunology · 13
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Evolutionary and expression analyses reveal a pattern of ancient duplications and functional specializations in the diversification of the Downstream of Kinase (DOK) genes
2018 · Geoffrey Guittard, Pierre Pontarotti, et al. · Developmental & Comparative Immunology · 12
Enhanced T-cell activation and differentiation in lymphocytes from transgenic mice expressing ubiquitination-resistant 2KR LAT molecules
2015 · A B Rodriguez-Peña, J Gomez-Rodriguez, et al. · Gene Therapy · 12
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TET2 regulates immune tolerance in chronically activated mast cells
2022 · Riccardo Rigo, Rabie Chelbi, et al. · JCI Insight · 9
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An Emerging Role for PI5P in T Cell Biology
2013 · Jacques A. Nunès, Geoffrey Guittard · Frontiers in Immunology · 9
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Targeting CISH enhances natural cytotoxicity receptor signaling and reduces NK cell exhaustion to improve solid tumor immunity
2021 · P-L. Bernard, R. B. Delconte, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 7
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Cish actively silences tcr signaling in CD8+ T cells to maintain tumor tolerance
2015 · Douglas Palmer, Geoff Guittard, et al. · Journal for ImmunoTherapy of Cancer · 6
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Works count: 73
Citation count: 1,707
H-index: 17
I10-index: 21
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