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Jay Christopher Horvat

Observed names: Horvat, JC, Horvat, Jay C, Horvat, Jay C., J C Horvat, J Horvat, J. C. Horvat, J. Horvat, J.C. Horvat, JAY C. HORVAT, JC Horvat, Jay C Horvat, Jay C. Horvat, Jay C. Horvat (157694), Jay Horvat, Jay C. Horvat
ORCID: 0000-0002-8526-0631
Observed ORCID: 0000-0002-8526-0631
OpenAlex ID: A5015543605
Immunological decision‐making: how does the immune system decide to mount a helper T‐cell response?
2007 · Gerard E. Kaiko, Jay C. Horvat, et al. · Immunology · 680
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Role for NLRP3 Inflammasome–mediated, IL-1β–Dependent Responses in Severe, Steroid-Resistant Asthma
2017 · Richard Y. Kim, James W. Pinkerton, et al. · American Journal of Respiratory and Critical Care Medicine · 458
Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages
2022 · Marah C. Runtsch, Stefano Angiari, et al. · Cell Metabolism · 343
Interferon-ε Protects the Female Reproductive Tract from Viral and Bacterial Infection
2013 · Ka Yee Fung, Niamh E. Mangan, et al. · Science · 268
A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis
2013 · Emma L. Beckett, Richard L. Stevens, et al. · Journal of Allergy and Clinical Immunology · 248
MicroRNA-21 drives severe, steroid-insensitive experimental asthma by amplifying phosphoinositide 3-kinase–mediated suppression of histone deacetylase 2
2016 · Richard Y. Kim, Jay C. Horvat, et al. · Journal of Allergy and Clinical Immunology · 211
Necroptosis Signaling Promotes Inflammation, Airway Remodeling, and Emphysema in Chronic Obstructive Pulmonary Disease
2021 · Zhe Lu, Hannelore P. Van Eeckhoutte, et al. · American Journal of Respiratory and Critical Care Medicine · 200
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Understanding the pathogenesis of occupational coal and silica dust-associated lung disease
2022 · Kanth Swaroop Vanka, Shakti Shukla, et al. · European Respiratory Review · 193
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Inflammasomes in the lung
2017 · James W. Pinkerton, Richard Y. Kim, et al. · Molecular Immunology · 170
Haemophilus influenzae Infection Drives IL-17-Mediated Neutrophilic Allergic Airways Disease
2011 · Ama-Tawiah Essilfie, Jodie L. Simpson, et al. · PLoS Pathogens · 167
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Evidence for Local and Systemic Immune Activation in Functional Dyspepsia and the Irritable Bowel Syndrome: A Systematic Review
2018 · Grace Burns, Georgia Carroll, et al. · The American Journal of Gastroenterology · 149
Fibulin-1 regulates the pathogenesis of tissue remodeling in respiratory diseases
2016 · Gang Liu, Marion A. Cooley, et al. · JCI Insight · 146
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Critical role for iron accumulation in the pathogenesis of fibrotic lung disease
2020 · Md Khadem Ali, Richard Y Kim, et al. · The Journal of Pathology · 144
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Mechanisms and treatments for severe, steroid‐resistant allergic airway disease and asthma
2017 · Philip M. Hansbro, Richard Y. Kim, et al. · Immunological Reviews · 140
Saturated fatty acids, obesity, and the nucleotide oligomerization domain–like receptor protein 3 (NLRP3) inflammasome in asthmatic patients
2018 · Lisa G. Wood, Qian Li, et al. · Journal of Allergy and Clinical Immunology · 139
Macrolide therapy suppresses key features of experimental steroid-sensitive and steroid-insensitive asthma
2015 · Ama-Tawiah Essilfie, Jay C Horvat, et al. · Thorax · 138
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Inflammasomes in COPD and neutrophilic asthma
2015 · Richard Y Kim, James W Pinkerton, et al. · Thorax · 132
Neonatal Chlamydial Infection Induces Mixed T-Cell Responses That Drive Allergic Airway Disease
2007 · Jay C. Horvat, Kenneth W. Beagley, et al. · American Journal of Respiratory and Critical Care Medicine · 132
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A microRNA-21–mediated SATB1/S100A9/NF-κB axis promotes chronic obstructive pulmonary disease pathogenesis
2021 · Richard Y. Kim, Krishna P. Sunkara, et al. · Science Translational Medicine · 125
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Understanding the mechanisms of viral induced asthma: New therapeutic directions
2008 · Nicole G. Hansbro, Jay C. Horvat, et al. · Pharmacology & Therapeutics · 122
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Cellular mechanisms underlying steroid-resistant asthma
2019 · Ridhima Wadhwa, Kamal Dua, et al. · European Respiratory Review · 118
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Role of iron in the pathogenesis of respiratory disease
2017 · Md Khadem Ali, Richard Y. Kim, et al. · The International Journal of Biochemistry & Cell Biology · 114
Airway remodelling and inflammation in asthma are dependent on the extracellular matrix protein fibulin‐1c
2017 · Gang Liu, Marion A Cooley, et al. · The Journal of Pathology · 113
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Early-life chlamydial lung infection enhances allergic airways disease through age-dependent differences in immunopathology
2010 · Jay C. Horvat, Malcolm R. Starkey, et al. · Journal of Allergy and Clinical Immunology · 112
Crucial role for lung iron level and regulation in the pathogenesis and severity of asthma
2020 · Md. Khadem Ali, Richard Y. Kim, et al. · European Respiratory Journal · 106
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Works count: 211
Citation count: 7,855
H-index: 49
I10-index: 93
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