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Haitao Guo
Institution:
University of North Carolina at Chapel Hill
Observed institutions:
University of North Carolina at Chapel Hill,
National Yang Ming University,
UNC Lineberger Comprehensive Cancer Center,
Indiana University School of Medicine
ORCID:
0000-0002-2737-2723
Observed ORCID:
0000-0002-2737-2723
OpenAlex ID:
A5015609876
Inflammasomes: mechanism of action, role in disease, and therapeutics
2015
·
Haitao Guo
, Justin B Callaway
, et al.
·
Nature Medicine
·
3,320
PDF
NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes
2017
·
Leslie Freeman
, Haitao Guo
, et al.
·
The Journal of Experimental Medicine
·
397
HIV-1 Infection Induces Interleukin-1β Production via TLR8 Protein-dependent and NLRP3 Inflammasome Mechanisms in Human Monocytes
2014
·
Haitao Guo
, Jianmei Gao
, et al.
·
Journal of Biological Chemistry
·
160
PDF
NLRX1 Sequesters STING to Negatively Regulate the Interferon Response, Thereby Facilitating the Replication of HIV-1 and DNA Viruses
2016
·
Haitao Guo
, Renate König
, et al.
·
Cell Host & Microbe
·
153
Multi-omics analyses reveal that HIV-1 alters CD4+ T cell immunometabolism to fuel virus replication
2021
·
Haitao Guo
, Qi Wang
, et al.
·
Nature Immunology
·
117
Plasmacytoid Dendritic Cells Suppress HIV-1 Replication but Contribute to HIV-1 Induced Immunopathogenesis in Humanized Mice
2014
·
Guangming Li
, Menglan Cheng
, et al.
·
PLoS Pathogens
·
108
PDF
NLRP12 Regulates Anti-viral RIG-I Activation via Interaction with TRIM25
2019
·
Szu-Ting Chen
, Szu-Ting Chen
, et al.
·
Cell Host & Microbe
·
97
NLRX1 promotes immediate IRF1-directed antiviral responses by limiting dsRNA-activated translational inhibition mediated by PKR
2017
·
Hui Feng
, Erik M Lenarcic
, et al.
·
Nature Immunology
·
93
The Innate Immune Sensor NLRC3 Acts as a Rheostat that Fine-Tunes T Cell Responses in Infection and Autoimmunity
2018
·
Toru Uchimura
, Yoshitaka Oyama
, et al.
·
Immunity
·
80
PDF
An epithelial-immune circuit amplifies inflammasome and IL-6 responses to SARS-CoV-2
2022
·
Katherine C. Barnett
, Yuying Xie
, et al.
·
Cell Host & Microbe
·
75
TRAF3IP3 negatively regulates cytosolic RNA induced anti-viral signaling by promoting TBK1 K48 ubiquitination
2020
·
Meng Deng
, Jason W. Tam
, et al.
·
Nature Communications
·
64
PDF
Platelet-activating factor (PAF) mediates NLRP3-NEK7 inflammasome induction independently of PAFR
2019
·
Meng Deng
, Haitao Guo
, et al.
·
The Journal of Experimental Medicine
·
55
NLRX1 negatively modulates type I IFN to facilitate KSHV reactivation from latency
2017
·
Zhe Ma
, Sharon E. Hopcraft
, et al.
·
PLoS Pathogens
·
32
PDF
Inflammasome Assays In Vitro and in Mouse Models
2020
·
Haitao Guo
, Jenny P.‐Y. Ting
·
Current Protocols in Immunology
·
28
PDF
Immune Checkpoint Axes Are Dysregulated in Patients With Alcoholic Hepatitis
2020
·
Wei Li
, Ying Xia
, et al.
·
Hepatology Communications
·
17
PDF
Analysis of human innate immune responses to PRINT fabricated nanoparticles with cross validation using a humanized mouse model
2015
·
Gregory R. Robbins
, Reid A. Roberts
, et al.
·
Nanomedicine Nanotechnology Biology and Medicine
·
14
PDF
Bi-directional epithelial-immune communication amplifies inflammasome activation and IL-6 release during SARS-CoV-2 infection
2023
·
Katherine Camille Barnett
, Yuying Xie
, et al.
·
The Journal of Immunology
PDF
TRAF3IP3 negatively regulates type I interferon signaling by suppressing TBK1
2019
·
Meng Deng
, Jason W. Tam
, et al.
·
The Journal of Immunology
NLRX1 Facilitates HIV-1 Infection of CD4 T Cells by Promoting Oxidative Phosphorylation
2019
·
Haitao Guo
, Qi Wang
, et al.
·
The Journal of Immunology
Platelet activating factor as a novel danger signal for activation of NLRP3 inflammasome
2018
·
Meng Deng
, W June Brickey
, et al.
·
The Journal of Immunology
NLRX1 promotes HIV-1 and DNA viruses replication by blocking STING-TBK1 innate immune signaling
2017
·
Meng Deng
, Haitao Guo
, et al.
·
The Journal of Immunology
A role for the NLR family members NLRC4 and NLRP3 in sterile inflammasome activation in glial cells
2017
·
Haitao Guo
, Leslie Freeman
, et al.
·
The Journal of Immunology
Myelin-Basic Protein-reactive Specific CD4 þ and CD8 þ NK Lymphocytes Induce Morphological Changes in Neuronal Cell Bodies and Myelin Sheaths: Implications for Multiple Sclerosis
2008
·
Quanyu Zhang
, Huang Jinghui
, et al.
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Works count:
23
Citation count:
4,808
H-index:
15
I10-index:
16
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