Author

René A. J. Crans

Observed names: René A.J. Crans, René Albert Johan Crans, RenéA. J. Crans

Institutions: Barcelona Institute of Science and Technology, Centre for Genomic Regulation

Observed institutions: University of Antwerp, Ghent University, Institut d'Investigació Biomédica de Bellvitge, Barcelona Institute of Science and Technology, Centre for Genomic Regulation, Universitat de Barcelona

ORCID: 0000-0003-2832-4405

Observed ORCID: 0000-0003-2832-4405

OpenAlex ID: A5015809600

Epigenetic silencing of triple negative breast cancer hallmarks by Withaferin A

2017 · Katarzyna Szarc vel Szic, Ken Declerck, et al. · Oncotarget · 70

Luminescence- and Fluorescence-Based Complementation Assays to Screen for GPCR Oligomerization: Current State of the Art

2019 · Elise Wouters, Lakshmi Vasudevan, et al. · International Journal of Molecular Sciences · 41

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Synthesis toward Bivalent Ligands for the Dopamine D2 and Metabotropic Glutamate 5 Receptors

2018 · Mingcheng Qian, Elise Wouters, et al. · Journal of Medicinal Chemistry · 26

Striatal Dopamine D2-Muscarinic Acetylcholine M1 Receptor–Receptor Interaction in a Model of Movement Disorders

2020 · René A. J. Crans, Elise Wouters, et al. · Frontiers in Pharmacology · 25

The mGlu5 Receptor Protomer-Mediated Dopamine D2 Receptor Trans-Inhibition Is Dependent on the Adenosine A2A Receptor Protomer: Implications for Parkinson’s Disease

2022 · Wilber Romero-Fernandez, Jaume J. Taura, et al. · Molecular Neurobiology · 15

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Disease‐specific neuropathological alterations of the locus coeruleus in Alzheimer's disease, Down syndrome, and Parkinson's disease

2025 · Marta Fructuoso, Yannick Vermeiren, et al. · Alzheimer s & Dementia · 12

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The validation of Short Interspersed Nuclear Elements (SINEs) as a RT-qPCR normalization strategy in a rodent model for temporal lobe epilepsy

2019 · René A. J. Crans, Jana Janssens, et al. · PLoS ONE · 12

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Evaluating the applicability of mouse SINEs as an alternative normalization approach for RT-qPCR in brain tissue of the APP23 model for Alzheimer’s disease

2019 · Jana Janssens, René A.J. Crans, et al. · Journal of Neuroscience Methods · 10

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Kainic acid-induced status epilepticus decreases mGlu5 receptor and phase-specifically downregulates Homer1b/c expression

2019 · René A.J. Crans, Sofie Daelemans, et al. · Brain Research · 8

Dopaminergic-cholinergic imbalance in movement disorders: a role for the novel striatal dopamine D 2 - muscarinic acetylcholine M 1 receptor heteromer

2020 · Francisco Ciruela, RenéA. J. Crans · Neural Regeneration Research · 7

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Corrigendum: Striatal dopamine D2-muscarinic acetylcholine M1 receptor-receptor interaction in a model of movement disorders

2022 · René A. J. Crans, Elise Wouters, et al. · Frontiers in Pharmacology · 1

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HDAC inhibitor treatment restores transcriptome, chromatin accessibility, and memory deficits in a mouse model for Down syndrome

2026 · Cesar Sierra, René A.J. Crans, et al. · iScience

Common pathogenic mechanisms in the hippocampus across neurodegenerative dementias: Alzheimer’s disease, Down syndrome, and Parkinson’s disease

2026 · René A. J. Crans, Marta Fructuoso, et al. · npj Dementia

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CNS disorders validation and application of methods for GPCR expression and interactions

2020 · René A. J. Crans · Ghent University Academic Bibliography (Ghent University)

Heterodimerization between dopamine D2 receptor and M1 muscarinic acetylcholine receptor

2016 · René Albert Johan Crans · Intrinsic Activity

Abstract LB-154: Epigenetic silencing of triple-negative breast cancer hallmarks by Withaferin A

2016 · Wim Vanden Berghe, Katarzyna Szarc vel Szic, et al. · Cancer Research

Works count: 16

Citation count: 227

H-index: 8

I10-index: 8