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James W. Gilbert

Observed names: Gilbert, James, James Gilbert, James W Gilbert
ORCID: 0000-0003-3580-6891
Observed ORCID: 0000-0003-3580-6891
OpenAlex ID: A5015827923
Viral contamination in biologic manufacture and implications for emerging therapies
2020 · Paul W. Barone, Michael E. Wiebe, et al. · Nature Biotechnology · 212
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Hybridization Liquid Chromatography–Tandem Mass Spectrometry: An Alternative Bioanalytical Method for Antisense Oligonucleotide Quantitation in Plasma and Tissue Samples
2020 · Pei Li, Yuqing Gong, et al. · Analytical Chemistry · 67
Transvascular Delivery of Hydrophobically Modified siRNAs: Gene Silencing in the Rat Brain upon Disruption of the Blood-Brain Barrier
2018 · Bruno M.D.C. Godinho, Nils Henninger, et al. · Molecular Therapy · 62
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Pharmacokinetic Profiling of Conjugated Therapeutic Oligonucleotides: A High-Throughput Method Based Upon Serial Blood Microsampling Coupled to Peptide Nucleic Acid Hybridization Assay
2017 · Bruno M.D.C. Godinho, James W. Gilbert, et al. · Nucleic Acid Therapeutics · 52
PK-modifying anchors significantly alter clearance kinetics, tissue distribution, and efficacy of therapeutics siRNAs
2022 · Bruno M.D.C. Godinho, Emily G. Knox, et al. · Molecular Therapy — Nucleic Acids · 27
Comparative route of administration studies using therapeutic siRNAs show widespread gene modulation in Dorset sheep
2021 · Chantal M. Ferguson, Bruno M.D.C. Godinho, et al. · JCI Insight · 27
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Systematic analysis of siRNA and mRNA features impacting fully chemically modified siRNA efficacy
2025 · Sarah M Davis, Samuel Hildebrand, et al. · Nucleic Acids Research · 25
RNAi-mediated silencing of SOD1 profoundly extends survival and functional outcomes in ALS mice
2025 · Alexandra Weiss, James W. Gilbert, et al. · Molecular Therapy · 18
Identification of selective and non-selective C9ORF72 targeting in vivo active siRNAs
2024 · James W. Gilbert, Zachary Kennedy, et al. · Molecular Therapy — Nucleic Acids · 9
Intrathecal Delivery of Therapeutic Oligonucleotides for Potent Modulation of Gene Expression in the Central Nervous System
2022 · Zachary Kennedy, James W. Gilbert, et al. · Methods in molecular biology · 4
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Works count: 11
Citation count: 503
H-index: 9
I10-index: 8
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