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Dennis Löffler

Observed names: D Löffler, D. Löffler, Dennis Loeffler, Dennis Löffler, Löffler, Dennis
Observed institutions: Friedrich-Alexander-Universität Erlangen-Nürnberg, Leipzig Heart Institute, University Hospital Leipzig, IFB Adiposity Diseases, Fraunhofer Institute for Cell Therapy and Immunology, University of Rostock, Martin Luther University Halle-Wittenberg, Leipzig University
ORCID: 0009-0003-8493-2189
Observed ORCID: 0009-0003-8493-2189
OpenAlex ID: A5015937355
Interleukin-6–dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer
2007 · Dennis Löffler, Katja Brocke-Heidrich, et al. · Blood · 653
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Serum Irisin Levels Are Regulated by Acute Strenuous Exercise
2015 · Dennis Löffler, Ulrike Müller, et al. · The Journal of Clinical Endocrinology & Metabolism · 223
Evidence of Early Alterations in Adipose Tissue Biology and Function and Its Association With Obesity-Related Inflammation and Insulin Resistance in Children
2014 · Kathrin Landgraf, Denise Rockstroh, et al. · Diabetes · 196
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Interleukin-6–dependent gene expression profiles in multiple myeloma INA-6 cells reveal a Bcl-2 family–independent survival pathway closely associated with Stat3 activation
2003 · Katja Brocke-Heidrich, Antje K. Kretzschmar, et al. · Blood · 154
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STAT3 is essential for Hodgkin lymphoma cell proliferation and is a target of tyrphostin AG17 which confers sensitization for apoptosis
2005 · U Holtick, M Vockerodt, et al. · Leukemia · 100
BCL3 is induced by IL-6 via Stat3 binding to intronic enhancer HS4 and represses its own transcription
2006 · K Brocke-Heidrich, B Ge, et al. · Oncogene · 87
METRNL decreases during adipogenesis and inhibits adipocyte differentiation leading to adipocyte hypertrophy in humans
2016 · D Löffler, K Landgraf, et al. · International Journal of Obesity · 65
Cyclophilins contribute to Stat3 signaling and survival of multiple myeloma cells
2009 · K Bauer, A K Kretzschmar, et al. · Oncogene · 62
Functional and clinical relevance of novel and known PCSK1 variants for childhood obesity and glucose metabolism
2016 · Dennis Löffler, Susanne Behrendt, et al. · Molecular Metabolism · 53
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Multiomic profiling of T cell lymphoma after therapy with anti-BCMA CAR T cells and GPRC5D-directed bispecific antibody
2025 · Till Braun, Michael Rade, et al. · Nature Medicine · 49
Regulation of human adipogenesis by miR125b-5p
2016 · Denise Rockstroh, Dennis Löffler, et al. · Adipocyte · 34
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ProstaTrend—A Multivariable Prognostic RNA Expression Score for Aggressive Prostate Cancer
2020 · Markus Kreuz, Dominik J. Otto, et al. · European Urology · 28
A time-resolved meta-analysis of consensus gene expression profiles during human T-cell activation
2023 · Michael Rade, Sebastian Böhlen, et al. · Genome biology · 25
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A novelFoxD3Variant Is Associated With Vitiligo and Elevated Thyroid Auto-Antibodies
2015 · Jo Ana Schunter, Dennis Löffler, et al. · The Journal of Clinical Endocrinology & Metabolism · 25
Impact of Metabolic Regulators on the Expression of the Obesity Associated Genes FTO and NAMPT in Human Preadipocytes and Adipocytes
2011 · Daniela Friebe, Dennis Löffler, et al. · PLoS ONE · 24
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Low Energy Electron Irradiation Is a Potent Alternative to Gamma Irradiation for the Inactivation of (CAR-)NK-92 Cells in ATMP Manufacturing
2021 · Lia Walcher, Ann-Kathrin Kistenmacher, et al. · Frontiers in Immunology · 22
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NAMPT serum levels are selectively elevated in acute infectious disease and in acute relapse of chronic inflammatory diseases in children
2017 · Julia Gesing, Kathrin Scheuermann, et al. · PLoS ONE · 21
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The BDNF Val66Met polymorphism is associated with lower BMI, lower postprandial glucose levels and elevated carbohydrate intake in children and adolescents
2017 · A. Kalenda, K. Landgraf, et al. · Pediatric Obesity · 19
Transcriptomic signatures reveal a shift towards an anti-inflammatory gene expression profile but also the induction of type I and type II interferon signaling networks through aryl hydrocarbon receptor activation in murine macrophages
2023 · Johannes R. Schmidt, Janine Haupt, et al. · Frontiers in Immunology · 16
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Adipocyte C1QTNF5 expression is BMI-dependently related to early adipose tissue dysfunction and systemic CTRP5 serum levels in obese children
2017 · J T Schwartze, K Landgraf, et al. · International Journal of Obesity · 16
Modulation of triglyceride accumulation in adipocytes by psychopharmacological agents in vitro
2015 · Dennis Löffler, Kathrin Landgraf, et al. · Journal of Psychiatric Research · 16
CAR T-cell therapy induces remission in multiorgan IgG4-related disease with hepatobiliary involvement
2025 · Verena Keitel, Michael C. Kreissl, et al. · Journal of Hepatology · 15
Insulin-Like Peptide 5 Interacts with Sex Hormones and Metabolic Parameters in a Gender and Adiposity Dependent Manner in Humans
2016 · I. Wagner, G. Flehmig, et al. · Hormone and Metabolic Research · 15
Microglia-Derived Extracellular Vesicles from Alzheimer’s Disease Patients Carry miRNAs Driving a Neuroinflammatory Response
2026 · Skaiste Arbaciauskaite, Simona Silvestri, et al. · Molecular Neurobiology · 14
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Atypical fibroxanthoma and pleomorphic dermal sarcoma – gene expression analysis compared with undifferentiated cutaneous squamous cell carcinoma
2023 · Iris Marie Anders, Carolin Schimmelpfennig, et al. · JDDG Journal der Deutschen Dermatologischen Gesellschaft · 13
Works count: 71
Citation count: 1,998
H-index: 18
I10-index: 26
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