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Author

Gary P. Brennan

Observed names: Brennan, Gary, Brennan, Gary P., GP Brennan, Gary Brennan, Gary P Brennan, Gary Patrick Brennan, Gary P. Brennan
Observed institutions: University College Dublin, Royal College of Surgeons in Ireland, Science Foundation Ireland, University of California, Irvine, Trinity College Dublin, Pediatrics and Genetics
ORCID: 0000-0002-4262-0481
Observed ORCID: 0000-0002-4262-0481
OpenAlex ID: A5015998521
MicroRNAs as regulators of brain function and targets for treatment of epilepsy
2020 · Gary P. Brennan, David C. Henshall · Nature Reviews Neurology · 171
The transcription factor NRSF contributes to epileptogenesis by selective repression of a subset of target genes
2014 · Shawn McClelland, Gary P Brennan, et al. · eLife · 139
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Reduced Mature MicroRNA Levels in Association with Dicer Loss in Human Temporal Lobe Epilepsy with Hippocampal Sclerosis
2012 · Ross C. McKiernan, Eva M. Jimenez-Mateos, et al. · PLoS ONE · 129
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Dual and Opposing Roles of MicroRNA-124 in Epilepsy Are Mediated through Inflammatory and NRSF-Dependent Gene Networks
2016 · Gary P. Brennan, Deblina Dey, et al. · Cell Reports · 116
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Dual-center, dual-platform microRNA profiling identifies potential plasma biomarkers of adult temporal lobe epilepsy
2018 · Rana Raoof, Sebastian Bauer, et al. · EBioMedicine · 113
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A microRNA‐129‐5p/Rbfox crosstalk coordinates homeostatic downscaling of excitatory synapses
2017 · Marek Rajman, Franziska Metge, et al. · The EMBO Journal · 107
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Rapid, Coordinate Inflammatory Responses after Experimental Febrile Status Epilepticus: Implications for Epileptogenesis
2015 · Katelin P. Patterson, Gary P. Brennan, et al. · eNeuro · 75
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microRNAs in the pathophysiology of epilepsy
2017 · Gary P. Brennan, David C. Henshall · Neuroscience Letters · 74
Regulatory Mechanisms of the RNA Modification m6A and Significance in Brain Function in Health and Disease
2021 · Justine Mathoux, David C. Henshall, et al. · Frontiers in Cellular Neuroscience · 70
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Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Channels in Epilepsy
2016 · Gary P. Brennan, Tallie Z. Baram, et al. · Cold Spring Harbor Perspectives in Medicine · 68
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A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy
2020 · Morten T. Venø, Cristina R. Reschke, et al. · Proceedings of the National Academy of Sciences · 64
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Enduring Memory Impairments Provoked by Developmental Febrile Seizures Are Mediated by Functional and Structural Effects of Neuronal Restrictive Silencing Factor
2017 · Katelin P. Patterson, Jeremy M. Barry, et al. · Journal of Neuroscience · 61
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Genome-wide microRNA profiling of plasma from three different animal models identifies biomarkers of temporal lobe epilepsy
2020 · Gary P. Brennan, Sebastian Bauer, et al. · Neurobiology of Disease · 55
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Transgenic Overexpression of 14-3-3 Zeta Protects Hippocampus against Endoplasmic Reticulum Stress and Status Epilepticus In Vivo
2013 · Gary P. Brennan, Eva M. Jimenez-Mateos, et al. · PLoS ONE · 47
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Epigenetic principles underlying epileptogenesis and epilepsy syndromes
2020 · Karen Conboy, David C. Henshall, et al. · Neurobiology of Disease · 46
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The Role of Sirt1 in Epileptogenesis
2017 · Alicia M. Hall, Gary P. Brennan, et al. · eNeuro · 45
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Systemic delivery of antagomirs during blood-brain barrier disruption is disease-modifying in experimental epilepsy
2021 · Cristina R. Reschke, Luiz F.A. Silva, et al. · Molecular Therapy · 43
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Antagonizing Increased miR-135a Levels at the Chronic Stage of Experimental TLE Reduces Spontaneous Recurrent Seizures
2019 · Vamshidhar R. Vangoor, Cristina R. Reschke, et al. · Journal of Neuroscience · 40
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A calcium-sensitive feed-forward loop regulating the expression of the ATP-gated purinergic P2X7 receptor via specificity protein 1 and microRNA-22
2016 · Tobias Engel, Gary P. Brennan, et al. · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 37
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CHD2-Related CNS Pathologies
2021 · Marc-Michel Wilson, David C. Henshall, et al. · International Journal of Molecular Sciences · 36
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Altered Biogenesis and MicroRNA Content of Hippocampal Exosomes Following Experimental Status Epilepticus
2020 · Aasia Batool, Thomas D. M. Hill, et al. · Frontiers in Neuroscience · 36
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Genetic deletion of microRNA-22 blunts the inflammatory transcriptional response to status epilepticus and exacerbates epilepsy in mice
2020 · Luiz F. Almeida Silva, Cristina R. Reschke, et al. · Molecular Brain · 29
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Spatiotemporal progression of ubiquitin-proteasome system inhibition after status epilepticus suggests protective adaptation against hippocampal injury
2017 · Tobias Engel, Jaime Martinez-Villarreal, et al. · Molecular Neurodegeneration · 28
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Multiple Disruptions of Glial-Neuronal Networks in Epileptogenesis That Follows Prolonged Febrile Seizures
2021 · Gary P. Brennan, Megan M. Garcia-Curran, et al. · Frontiers in Neurology · 25
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Temporally Altered miRNA Expression in a Piglet Model of Hypoxic Ischemic Brain Injury
2020 · Sophie Casey, Kate Goasdoue, et al. · Molecular Neurobiology · 24
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Works count: 52
Citation count: 1,793
H-index: 24
I10-index: 28
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