Author

Helena Gauani

Observed name: H. Gauani

Institution: Insmed (United States)

Observed institution: Insmed (United States)

ORCID: 0000-0001-9216-6902

Observed ORCID: 0000-0001-9216-6902

OpenAlex ID: A5016058184

Inhaled hexadecyl-treprostinil provides pulmonary vasodilator activity at significantly lower plasma concentrations than infused treprostinil

2018 · Richard W. Chapman, Zhili Li, et al. · Pulmonary Pharmacology & Therapeutics · 24

Development and Characterization of Treprostinil Palmitil Inhalation Aerosol for the Investigational Treatment of Pulmonary Arterial Hypertension

2021 · Adam J. Plaunt, Sadikul Islam, et al. · International Journal of Molecular Sciences · 17

Treprostinil palmitil inhibits the hemodynamic and histopathological changes in the pulmonary vasculature and heart in an animal model of pulmonary arterial hypertension

2021 · Michel R. Corboz, Adam J. Plaunt, et al. · European Journal of Pharmacology · 8

Effect of Inhalation Profile on Delivery of Treprostinil Palmitil Inhalation Powder

2023 · Helena Gauani, Thomas Baker, et al. · Pharmaceutics · 7

Assessment of Inhaled Treprostinil Palmitil, Inhaled and Intravenous Treprostinil, and Oral Selexipag in a Sugen/Hypoxia Rat Model of Pulmonary Arterial Hypertension

2022 · Michel R. Corboz, Adam J. Plaunt, et al. · Journal of Pharmacology and Experimental Therapeutics · 6

Evaluation and Selection of the Inhaler Device for Treprostinil Palmitil Inhalation Powder

2022 · Helena Gauani, Thomas Baker, et al. · Frontiers in Drug Delivery · 6

Treprostinil palmitil, an inhaled long-acting pulmonary vasodilator, does not show tachyphylaxis with daily dosing in rats

2020 · Richard W. Chapman, Zhili Li, et al. · Pulmonary Pharmacology & Therapeutics · 5

Preclinical Investigation of a Lipoglycopeptide Dry Powder Inhalation Therapy for the Treatment of Pulmonary MRSA Infection

2023 · Donna M. Konicek, Adam J. Plaunt, et al. · Pharmaceutics · 2

Beneficial Effects of Treprostinil Palmitil in a Sugen/Hypoxia Rat Model of Pulmonary Arterial Hypertension; a Comparison with Inhaled and Intravenous Treprostinil and Oral Selexipag

2021 · M.R. Corboz, A.J. Plaunt, et al. · American Journal of Respiratory and Critical Care Medicine · 2

Cough and airway irritation with inhaled treprostinil does not involve activation of laryngeal reflexes.

2018 · Richard W. Chapman, Walter R. Perkins, et al. · European Respiratory Journal · 2

Inhalation of dry powder INS1009 (DP-INS1009) does not activate the cough reflex in guinea pigs: a comparison with nebulized treprostinil

2017 · Michel Corboz, Richard Chapman, et al. · European Respiratory Journal · 2

No evidence of desensitization to repeat dosing with treprostinil palmitil inhalation suspension (TPIS) for 32-consecutive days in hypoxia-challenged telemetered rats

2020 · Richard W Chapman, Michel Corboz, et al. · European Respiratory Journal · 1

Comparison of Treprostinil Palmitil Inhalation Suspension (TPIS) or Oral Sildenafil (Sild) in a Sugen/Hypoxia Rat Model of PAH

2020 · Michel Corboz, Sandra Gagnon, et al. · European Respiratory Journal · 1

Pulmonary Vasodilator Activity of Inhaled Treprostinil Palmitil, Inhaled Treprostinil, Intravenous Treprostinil and Oral Selexipag in Hypoxia-Challenged Rats

2021 · M.R. Corboz, A.J. Plaunt, et al. · American Journal of Respiratory and Critical Care Medicine

Works count: 14

Citation count: 83

H-index: 6

I10-index: 2