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Roshan L. Shrestha
Observed names:
Roshan L Shrestha,
Roshan Lal Shrestha,
Roshan Shreshta,
Roshan Shrestha,
Roshan L. Shrestha
Institutions:
National Institutes of Health,
National Cancer Institute,
Center for Cancer Research
Observed institutions:
National Institutes of Health,
University of Cambridge,
Government of the United States of America,
National Cancer Institute,
National Cancer Institute,
Center for Cancer Research
show all 6
ORCID:
0000-0001-7597-9418
Observed ORCIDs:
0000-0001-7597-9418,
0000-0001-5093-9460
OpenAlex ID:
A5016311892
Lateral to End-on Conversion of Chromosome-Microtubule Attachment Requires Kinesins CENP-E and MCAK
2013
·
Roshan L. Shrestha
, Viji M. Draviam
·
Current Biology
·
137
PDF
Mislocalization of centromeric histone H3 variant CENP-A contributes to chromosomal instability (CIN) in human cells
2017
·
Roshan L. Shrestha
, Grace S. Ahn
, et al.
·
Oncotarget
·
130
PDF
Aurora-B kinase pathway controls the lateral to end-on conversion of kinetochore-microtubule attachments in human cells
2017
·
Roshan L. Shrestha
, Duccio Conti
, et al.
·
Nature Communications
·
80
PDF
CENP-A overexpression promotes aneuploidy with karyotypic heterogeneity
2021
·
Roshan L. Shrestha
, Austin Rossi
, et al.
·
The Journal of Cell Biology
·
63
High-speed microscopy with an electrically tunable lens to image the dynamics of in vivo molecular complexes
2015
·
Yuichiro Nakai
, Mitsunori Ozeki
, et al.
·
Review of Scientific Instruments
·
49
PDF
A Semi-Supervised Approach for Refining Transcriptional Signatures of Drug Response and Repositioning Predictions
2015
·
Francesco Iorio
, Roshan L. Shrestha
, et al.
·
PLoS ONE
·
45
PDF
Kindlin1 regulates microtubule function to ensure normal mitosis
2016
·
Hitesh Patel
, Ifigeneia Stavrou
, et al.
·
Journal of Molecular Cell Biology
·
31
TAO1 kinase maintains chromosomal stability by facilitating proper congression of chromosomes
2014
·
Roshan L. Shrestha
, Naoka Tamura
, et al.
·
Open Biology
·
28
Automated tracking of mitotic spindle pole positions shows that LGN is required for spindle rotation but not orientation maintenance
2013
·
Adam M Corrigan
, Roshan L Shrestha
, et al.
·
Cell Cycle
·
24
PDF
DNAJC9 prevents CENP-A mislocalization and chromosomal instability by maintaining the fidelity of histone supply chains
2024
·
Vinutha Balachandra
, Roshan L Shrestha
, et al.
·
The EMBO Journal
·
23
PDF
Spindle rotation in human cells is reliant on a MARK2-mediated equatorial spindle-centering mechanism
2018
·
Ihsan Zulkipli
, Joanna Clark
, et al.
·
The Journal of Cell Biology
·
19
PDF
The histone H3/H4 chaperone CHAF1B prevents the mislocalization of CENP-A for chromosomal stability
2023
·
Roshan L. Shrestha
, Vinutha Balachandra
, et al.
·
Journal of Cell Science
·
18
PDF
Matrin3 regulates mitotic spindle dynamics by controlling alternative splicing of CDC14B
2023
·
Bruna R. Muys
, Roshan L. Shrestha
, et al.
·
Cell Reports
·
16
Counteraction between Astrin-PP1 and Cyclin-B-CDK1 pathways protects chromosome-microtubule attachments independent of biorientation
2021
·
Xinhong Song
, Duccio Conti
, et al.
·
Nature Communications
·
14
PDF
Context-Dependent Function of Long Noncoding RNA PURPL in Transcriptome Regulation during p53 Activation
2022
·
Corrine Corrina R. Hartford
, Roshan L. Shrestha
, et al.
·
Molecular and Cellular Biology
·
13
Modeling of Noisy Spindle Dynamics Reveals Separable Contributions to Achieving Correct Orientation
2015
·
Adam M. Corrigan
, Roshan Shrestha
, et al.
·
Biophysical Journal
·
13
PDF
MARK2/Par1b kinase present at centrosomes and retraction fibres corrects spindle off-centring induced by actin disassembly
2019
·
Madeleine Hart
, Ihsan Zulkipli
, et al.
·
Open Biology
·
12
PDF
How are Dynamic Microtubules Stably Tethered to Human Chromosomes?
2017
·
Duccio Conti
, Madeleine Hart
, et al.
·
InTech eBooks
·
8
PDF
β-TrCP-Mediated Proteolysis of Mis18β Prevents Mislocalization of CENP-A and Chromosomal Instability
2024
·
Subhash Chandra Sethi
, Roshan Lal Shrestha
, et al.
·
Molecular and Cellular Biology
·
7
Lamin A/C loss promotes R-loop-mediated genomic instability and poor survival in small-cell lung cancer
2025
·
Christopher W. Schultz
, Sourav Saha
, et al.
·
Proceedings of the National Academy of Sciences
·
6
PDF
Mck1-mediated proteolysis of CENP-A prevents mislocalization of CENP-A for chromosomal stability in Saccharomyces cerevisiae
2024
·
Tianyi Zhang
, Wei-Chun Au
, et al.
·
Genetics
·
6
PDF
Blockade of Tumor-Intrinsic TGFβ Signaling Drives Hyperprogression in Small Cell Lung Cancer
2026
·
Brett A. Schroeder
, Chirayu Mohindroo
, et al.
·
Cancer Discovery
·
3
PDF
Durvalumab and cediranib with and without olaparib in recurrent ovarian cancer: a phase II proof-of-concept study
2026
·
Junya Tabata
, Tzu-Ting Huang
, et al.
·
Nature Communications
·
3
SARC031: A Phase II Trial of Selumetinib and Sirolimus for Patients with Unresectable or Metastatic Malignant Peripheral Nerve Sheath Tumors (MPNST)
2026
·
AeRang Kim
, Karla V. Ballman
, et al.
·
Clinical Cancer Research
·
3
PDF
Chromatin remodeling activity of EP400 safeguards chromosomal stability by preventing CENP-A mislocalization
2025
·
Subhash Chandra Sethi
, Roshan L. Shrestha
, et al.
·
Cell Reports
·
3
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Works count:
65
Citation count:
762
H-index:
14
I10-index:
17
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