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N. Yi Mok

Observed names: Mok, N. Yi, N Yi Mok, N. Yi Mok, N.Y. Mok, Ngai Mok, Ngai Y. Mok, Ngai Yi Mok, Yi Mok
Observed institutions: University of Leeds, Institute of Cancer Research, University of Dundee, Cancer Research UK, Institute of Cancer Research, BenevolentAI (United Kingdom), Wellcome Centre for Anti-Infectives Research
ORCID: 0000-0002-2827-3735
Observed ORCID: 0000-0002-2827-3735
OpenAlex ID: A5016688442
On the Origins of Three-Dimensionality in Drug-Like Molecules
2016 · Joshua Meyers, Michael Carter, et al. · Future Medicinal Chemistry · 119
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8-Substituted Pyrido[3,4- d ]pyrimidin-4(3 H )-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors
2016 · Vassilios Bavetsias, Rachel M. Lanigan, et al. · Journal of Medicinal Chemistry · 100
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A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N -Myristoyltransferase Inhibitors
2018 · Justin R. Harrison, Stephen Brand, et al. · Journal of Medicinal Chemistry · 58
Mining the ChEMBL Database: An Efficient Chemoinformatics Workflow for Assembling an Ion Channel-Focused Screening Library
2011 · N. Yi Mok, Ruth Brenk · Journal of Chemical Information and Modeling · 47
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Binding to an Unusual Inactive Kinase Conformation by Highly Selective Inhibitors of Inositol-Requiring Enzyme 1α Kinase-Endoribonuclease
2019 · Giampiero Colombano, John J. Caldwell, et al. · Journal of Medicinal Chemistry · 32
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Discovery of novel non-peptide inhibitors of BACE-1 using virtual high-throughput screening
2009 · N. Yi Mok, James Chadwick, et al. · Bioorganic & Medicinal Chemistry Letters · 32
HSF1 Pathway Inhibitor Clinical Candidate (CCT361814/NXP800) Developed from a Phenotypic Screen as a Potential Treatment for Refractory Ovarian Cancer and Other Malignancies
2023 · A. Elisa Pasqua, Swee Y. Sharp, et al. · Journal of Medicinal Chemistry · 29
Locating Sweet Spots for Screening Hits and Evaluating Pan-Assay Interference Filters from the Performance Analysis of Two Lead-like Libraries
2013 · N. Yi Mok, Sara Maxe, et al. · Journal of Chemical Information and Modeling · 23
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Discovery of Biphenylacetamide-Derived Inhibitors of BACE1 Using de Novo Structure-Based Molecular Design
2013 · N. Yi Mok, James Chadwick, et al. · Journal of Medicinal Chemistry · 20
C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-ones: Studies towards the identification of potent, cell penetrant Jumonji C domain containing histone lysine demethylase 4 subfamily (KDM4) inhibitors, compound profiling in cell-based target engagement assays
2019 · Yann-Vaï Le Bihan, Rachel M. Lanigan, et al. · European Journal of Medicinal Chemistry · 19
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Privileged Structures and Polypharmacology within and between Protein Families
2018 · Joshua Meyers, Nicola E. A. Chessum, et al. · ACS Medicinal Chemistry Letters · 18
Increasing the Coverage of Medicinal Chemistry-Relevant Space in Commercial Fragments Screening
2014 · N. Yi Mok, Ruth Brenk, et al. · Journal of Chemical Information and Modeling · 18
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Applications of Systematic Molecular Scaffold Enumeration to Enrich Structure–Activity Relationship Information
2016 · N. Yi Mok, Nathan Brown · Journal of Chemical Information and Modeling · 14
Optimisation of the Anti‐Trypanosoma brucei Activity of the Opioid Agonist U50488
2011 · Victoria C. Smith, Laura A. T. Cleghorn, et al. · ChemMedChem · 9
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Exploiting Vector Pattern Diversity of Molecular Scaffolds for Cheminformatics Tasks in Drug Discovery
2024 · Daniela Dolciami, Robert M. Ziolek, et al. · Journal of Chemical Information and Modeling · 7
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Pyrido[3,4-d]pyrimidin-4(3H)-one metabolism mediated by aldehyde oxidase is blocked by C2-substitution
2016 · Angela Hayes, N. Yi Mok, et al. · Xenobiotica · 7
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Metabolism of the dual FLT-3/Aurora kinase inhibitor CCT241736 in preclinical and human in vitro models: Implication for the choice of toxicology species
2019 · Francesca L. Wood, Sam Shepherd, et al. · European Journal of Pharmaceutical Sciences · 6
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Exploiting Vector Pattern Diversity of Molecular Scaffolds for Cheminformatics Tasks in Drug Discovery
2023 · Dolciami, Daniela, Ziolek, Robert M., et al. · Zenodo (CERN European Organization for Nuclear Research)
Crystal Structure of Leishmania major N-Myristoyltransferase (NMT) With Bound Myristoyl-CoA and a isopropyl methyl indole aryl sulphonamide ligand
2018 · D.A. Robinson, J.R. Harrison, et al. · Worldwide Protein Data Bank
P2‐482: De novo design of cellular active beta‐secretase inhibitors
2008 · Ngai Y. Mok, James Chadwick, et al. · Alzheimer s & Dementia
Works count: 22
Citation count: 558
H-index: 13
I10-index: 13
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