Get started
Author

Christian Lherbet

Observed names: C LHERBET, C. Lherbet, Lherbet, C., Lherbet, Christian
Observed institutions: Centre National de la Recherche Scientifique, Salk Institute for Biological Studies, Howard Hughes Medical Institute, Université Toulouse III - Paul Sabatier, University of Sciences and Technology Houari Boumediene, University of Utah, Ziane Achour University of Djelfa, Institut des Technologies Avancées en sciences du Vivant, Université de Toulouse, Synthèse et Physicochimie de Molécules d'Intérêt Biologique, Université de Montréal, University of Edinburgh
ORCID: 0000-0001-5427-5040
Observed ORCID: 0000-0001-5427-5040
OpenAlex ID: A5016842505
Synthesis, antimycobacterial screening and ligand-based molecular docking studies on novel pyrrole derivatives bearing pyrazoline, isoxazole and phenyl thiourea moieties
2015 · Shrinivas D. Joshi, Sheshagiri R. Dixit, et al. · European Journal of Medicinal Chemistry · 105
Synthesis and biological activities of triazole derivatives as inhibitors of InhA and antituberculosis agents
2011 · Christophe Menendez, Sylvain Gau, et al. · European Journal of Medicinal Chemistry · 102
Chemical synthesis and biological evaluation of triazole derivatives as inhibitors of InhA and antituberculosis agents
2012 · Christophe Menendez, Aurélien Chollet, et al. · European Journal of Medicinal Chemistry · 94
Mechanochemical Synthesis and Biological Evaluation of Novel Isoniazid Derivatives with Potent Antitubercular Activity
2017 · Paulo Oliveira, Brigitte Guidetti, et al. · Molecules · 92
PDF
Gamma‐Glutamyl Transpeptidase Substrate Specificity and Catalytic Mechanism
2005 · Jeffrey W. Keillor, Roselyne Castonguay, et al. · Methods in enzymology on CD-ROM/Methods in enzymology · 79
An overview on crystal structures of InhA protein: Apo-form, in complex with its natural ligands and inhibitors
2018 · Aurélien Chollet, Laurent Maveyraud, et al. · European Journal of Medicinal Chemistry · 66
Design, synthesis and evaluation of new GEQ derivatives as inhibitors of InhA enzyme and Mycobacterium tuberculosis growth
2015 · Aurélien Chollet, Giorgia Mori, et al. · European Journal of Medicinal Chemistry · 58
Discovery of hydrazone containing thiadiazoles as Mycobacterium tuberculosis growth and enoyl acyl carrier protein reductase (InhA) inhibitors
2020 · Hilal Doğan, Şengül Dilem Doğan, et al. · European Journal of Medicinal Chemistry · 54
Crystal structure of the enoyl-ACP reductase of Mycobacterium tuberculosis (InhA) in the apo-form and in complex with the active metabolite of isoniazid pre-formed by a biomimetic approach
2015 · Aurélien Chollet, Lionel Mourey, et al. · Journal of Structural Biology · 52
PDF
Design and synthesis of thiourea-based derivatives as Mycobacterium tuberculosis growth and enoyl acyl carrier protein reductase (InhA) inhibitors
2020 · Şengül Dilem Doğan, Miyase Gözde Gündüz, et al. · European Journal of Medicinal Chemistry · 51
PDF
Synthesis of 3-heteryl substituted pyrrolidine-2,5-diones via catalytic Michael reaction and evaluation of their inhibitory activity against InhA and Mycobacterium tuberculosis
2013 · Tetiana Matviiuk, Giorgia Mori, et al. · European Journal of Medicinal Chemistry · 51
Synthesis, characterization and antitubercular activities of novel pyrrolyl hydrazones and their Cu-complexes
2016 · Shrinivas D. Joshi, Devendra Kumar, et al. · European Journal of Medicinal Chemistry · 50
Design, chemical synthesis of 3-(9H-fluoren-9-yl)pyrrolidine-2,5-dione derivatives and biological activity against enoyl-ACP reductase (InhA) and Mycobacterium tuberculosis
2013 · Tetiana Matviiuk, Frédéric Rodriguez, et al. · European Journal of Medicinal Chemistry · 46
Pyrrolidinone and pyrrolidine derivatives: Evaluation as inhibitors of InhA and Mycobacterium tuberculosis
2016 · Tetiana Matviiuk, Jan Madacki, et al. · European Journal of Medicinal Chemistry · 42
Kinetic Characterization and Identification of the Acylation and Glycosylation Sites of Recombinant Human γ-Glutamyltranspeptidase
2007 · Roselyne Castonguay, Dany Halim, et al. · Biochemistry · 40
Pharmacophore mapping, molecular docking, chemical synthesis of some novel pyrrolyl benzamide derivatives and evaluation of their inhibitory activity against enoyl-ACP reductase (InhA) and Mycobacterium tuberculosis
2018 · Shrinivas D. Joshi, Sheshagiri R. Dixit, et al. · Bioorganic Chemistry · 37
Synthesis and evaluation of α-ketotriazoles and α,β-diketotriazoles as inhibitors of Mycobacterium tuberculosis
2013 · Christophe Menendez, Frédéric Rodriguez, et al. · European Journal of Medicinal Chemistry · 37
Bismuth Triflate as a Safe and Readily Handled Source of Triflic Acid: Application to the Oxa–Pictet–Spengler Reaction
2010 · Benaissa Bouguerne, Pascal Hoffmann, et al. · Synthetic Communications · 35
In Silico Repositioning of Cannabigerol as a Novel Inhibitor of the Enoyl Acyl Carrier Protein (ACP) Reductase (InhA)
2019 · Luca Pinzi, Christian Lherbet, et al. · Molecules · 34
Bismuth triflate-catalyzed oxa- and thia-Pictet–Spengler reactions: access to iso- and isothio-chroman compounds
2008 · Christian Lherbet, David Soupaya, et al. · Tetrahedron Letters · 34
Discovery of new diaryl ether inhibitors against Mycobacterium tuberculosis targeting the minor portal of InhA
2023 · Mélina Chebaiki, Evelyne Delfourne, et al. · European Journal of Medicinal Chemistry · 30
Discovery of novel N-methyl carbazole tethered rhodanine derivatives as direct inhibitors of Mycobacterium tuberculosis InhA
2019 · Mahamadhanif S. Shaikh, Ashish M. Kanhed, et al. · Bioorganic & Medicinal Chemistry Letters · 29
Insights into Substrate Modification by Dehydratases from Type I Polyketide Synthases
2017 · Alexandre Faille, Sabine Gavalda, et al. · Journal of Molecular Biology · 29
PDF
Kinetic Studies of Rat Kidney γ-Glutamyltranspeptidase Deacylation Reveal a General Base-Catalyzed Mechanism
2003 · Roselyne Castonguay, Christian Lherbet, et al. · Biochemistry · 29
First triclosan-based macrocyclic inhibitors of InhA enzyme
2019 · Frédéric Rodriguez, Nathalie Saffon, et al. · Bioorganic Chemistry · 28
PDF
Works count: 166
Citation count: 1,955
H-index: 27
I10-index: 50
Year
Topic
Type