Author

Stephen D. C. Griffin

Observed names: Griffin Stephen, Griffin, S, Griffin, Stephen, Professor Stephen Griffin, S D Griffin, S GRIFFIN, S. D. C. Griffin, S. Griffin, S.D.C. Griffin, Stephen D. Griffin, Stephen D.C. Griffin, Stephen Griffin

Institution: University of Leeds

Observed institutions: University of Leeds, Mayo Clinic, Institute of Cancer Research, University of Cambridge, Leiden University Medical Center, Cancer Research UK, St James's University Hospital, University of Surrey, Addenbrooke's Hospital, Institut de Biologie Moléculaire et Cellulaire, National Yang Ming University, Fundação Oswaldo Cruz, Oncolytics Biotech (Canada)

ORCID: 0000-0002-7233-5243

Observed ORCID: 0000-0002-7233-5243

OpenAlex ID: A5017014154

The p7 protein of hepatitis C virus forms an ion channel that is blocked by the antiviral drug, Amantadine

2002 · Stephen D.C. Griffin, Lucy P. Beales, et al. · FEBS Letters · 497

Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade

2018 · Adel Samson, Karen J. Scott, et al. · Science Translational Medicine · 374

A multinational Delphi consensus to end the COVID-19 public health threat

2022 · Jeffrey V. Lazarus, Diana Romero, et al. · Nature · 225

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Intracellular Proton Conductance of the Hepatitis C Virus p7 Protein and Its Contribution to Infectious Virus Production

2010 · Ann L. Wozniak, Stephen Griffin, et al. · PLoS Pathogens · 197

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A conserved basic loop in hepatitis C virus p7 protein is required for amantadine-sensitive ion channel activity in mammalian cells but is dispensable for localization to mitochondria

2004 · Stephen D. C. Griffin, Ruth Harvey, et al. · Journal of General Virology · 166

Enhanced hepatitis C virus genome replication and lipid accumulation mediated by inhibition of AMP-activated protein kinase

2010 · Jamel Mankouri, Philip R. Tedbury, et al. · Proceedings of the National Academy of Sciences · 151

Evidence for the Formation of a Heptameric Ion Channel Complex by the Hepatitis C Virus P7 Protein in Vitro

2006 · Dean Clarke, Stephen Griffin, et al. · Journal of Biological Chemistry · 139

Viroporins: structure, function and potential as antiviral targets

2015 · Claire Scott, Stephen Griffin · Journal of General Virology · 138

Genotype-dependent sensitivity of hepatitis C virus to inhibitors of the p7 ion channel

2008 · Stephen Griffin, Corine StGelais, et al. · Hepatology · 124

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High-Risk Human Papillomavirus E5 Oncoprotein Displays Channel-Forming Activity Sensitive to Small-Molecule Inhibitors

2012 · Laura F. Wetherill, Kristopher K. Holmes, et al. · Journal of Virology · 118

Vps4 and the ESCRT-III complex are required for the release of infectious hepatitis C virus particles

2009 · L. Corless, C. M. Crump, et al. · Journal of General Virology · 114

Modulation of calcium signaling pathway by hepatitis C virus core protein stimulates NLRP3 inflammasome activation

2019 · Amina A. Negash, Rebecca M. Olson, et al. · PLoS Pathogens · 107

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Domain III of NS5A contributes to both RNA replication and assembly of hepatitis C virus particles

2009 · Mair Hughes, Stephen Griffin, et al. · Journal of General Virology · 102

Internalization of Oncolytic Reovirus by Human Dendritic Cell Carriers Protects the Virus from Neutralization

2011 · Elizabeth J. Ilett, Montserrat Bárcena, et al. · Clinical Cancer Research · 97

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The Major Human Immunodeficiency Virus Type 2 (HIV-2) Packaging Signal Is Present on All HIV-2 RNA Species: Cotranslational RNA Encapsidation and Limitation of Gag Protein Confer Specificity

2001 · Stephen D. C. Griffin, Jane F. Allen, et al. · Journal of Virology · 93

Inhibition of hepatitis C virus p7 membrane channels in a liposome-based assay system

2007 · C STGELAIS, T TUTHILL, et al. · Antiviral Research · 82

Oncolytic reovirus as a combined antiviral and anti-tumour agent for the treatment of liver cancer

2016 · Adel Samson, Matthew J Bentham, et al. · Gut · 78

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Signal Peptide Cleavage and Internal Targeting Signals Direct the Hepatitis C Virus p7 Protein to Distinct Intracellular Membranes

2005 · Stephen Griffin, Dean Clarke, et al. · Journal of Virology · 77

Direct visualization of the small hydrophobic protein of human respiratory syncytial virus reveals the structural basis for membrane permeability

2010 · Stephen D. Carter, Kyle C. Dent, et al. · FEBS Letters · 76

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Resistance mutations define specific antiviral effects for inhibitors of the hepatitis C virus p7 ion channel

2011 · Toshana L. Foster, Mark Verow, et al. · Hepatology · 72

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Suppression of a pro-apoptotic K + channel as a mechanism for hepatitis C virus persistence

2009 · Jamel Mankouri, Mark L. Dallas, et al. · Proceedings of the National Academy of Sciences · 71

Determinants of Hepatitis C Virus p7 Ion Channel Function and Drug Sensitivity Identified In Vitro

2009 · Corine StGelais, Toshana L. Foster, et al. · Journal of Virology · 71

MicroRNA-18a targeting of the STK4/MST1 tumour suppressor is necessary for transformation in HPV positive cervical cancer

2020 · Ethan L. Morgan, Molly R. Patterson, et al. · PLoS Pathogens · 64

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Structure-Guided Design Affirms Inhibitors of Hepatitis C Virus p7 as a Viable Class of Antivirals Targeting Virion Release

2013 · Toshana L. Foster, Gary S. Thompson, et al. · Hepatology · 62

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Mosquito saliva enhances virus infection through sialokinin-dependent vascular leakage

2022 · Daniella A. Lefteri, Steven R. Bryden, et al. · Proceedings of the National Academy of Sciences · 59

Works count: 103

Citation count: 4,130

H-index: 33

I10-index: 52