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Sigrun Ruth Hofmann

Observed names: Hofmann, Sigrun Ruth, S Hofmann, S R Hofmann, S. Hofmann, S. R. Hofmann, S.R. Hofmann, Sigrun Hofmann, Sigrun Hofmann6, Sigrun R Hofmann, Sigrun R. Hofmann
Observed institutions: National Institutes of Health, National Institute of Arthritis and Musculoskeletal and Skin Diseases, Pediatrics and Genetics, Klinikum im Friedrichshain, University Hospital Carl Gustav Carus, Technische Universität Dresden
ORCID: 0000-0003-3128-1143
Observed ORCID: 0000-0003-3128-1143
OpenAlex ID: A5017070315
Critical Role for STAT4 Activation by Type 1 Interferons in the Interferon-γ Response to Viral Infection
2002 · Khuong B. Nguyen, Wendy T. Watford, et al. · Science · 504
Chronic Recurrent Multifocal Osteomyelitis (CRMO): Presentation, Pathogenesis, and Treatment
2017 · Sigrun R. Hofmann, Franz Kapplusch, et al. · Current Osteoporosis Reports · 321
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Jak3, severe combined immunodeficiency, and a new class of immunosuppressive drugs
2005 · Marko Pesu, Fabio Candotti, et al. · Immunological Reviews · 134
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Chronic non-bacterial osteomyelitis is associated with impaired Sp1 signaling, reduced IL10 promoter phosphorylation, and reduced myeloid IL-10 expression
2011 · S.R. Hofmann, T. Schwarz, et al. · Clinical Immunology · 109
Cytokines and their role in lymphoid development, differentiation and homeostasis
2002 · Sigrun R. Hofmann, Rachel Ettinger, et al. · Current Opinion in Allergy and Clinical Immunology · 103
Autoinflammatory mutation in NLRC4 reveals a leucine-rich repeat (LRR)–LRR oligomerization interface
2018 · Fiona Moghaddas, Ping Zeng, et al. · Journal of Allergy and Clinical Immunology · 72
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The molecular pathophysiology of chronic non-bacterial osteomyelitis (CNO)—a systematic review
2017 · Sigrun Ruth Hofmann, Franz Kapplusch, et al. · Molecular and Cellular Pediatrics · 67
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CD14+ monocytes contribute to inflammation in chronic nonbacterial osteomyelitis (CNO) through increased NLRP3 inflammasome expression
2018 · D. Brandt, E. Sohr, et al. · Clinical Immunology · 58
Jak3-Independent Trafficking of the Common γ Chain Receptor Subunit: Chaperone Function of Jaks Revisited
2004 · Sigrun R. Hofmann, Albert Q. Lam, et al. · Molecular and Cellular Biology · 55
Serum Interleukin-6 and CCL11/Eotaxin May Be Suitable Biomarkers for the Diagnosis of Chronic Nonbacterial Osteomyelitis
2017 · Sigrun Ruth Hofmann, Fanny Böttger, et al. · Frontiers in Pediatrics · 52
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Clinical Experiences with Low-Molecular Weight Heparins in Pediatric Patients
2001 · Sigrun Hofmann, Ralf Knoefler, et al. · Thrombosis Research · 45
Development of a Diagnostic Clinical Score for Hemodynamically Significant Patent Ductus Arteriosus
2017 · Annemarie Kindler, Barbara Seipolt, et al. · Frontiers in Pediatrics · 42
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Immune modulating effects of receptor interacting protein 2 (RIP2) in autoinflammation and immunity
2020 · Sigrun Ruth Hofmann, Leonie Girschick, et al. · Clinical Immunology · 39
Naturally Occurring Genetic Variants of Human Caspase-1 Differ Considerably in Structure and the Ability to Activate Interleukin-1β
2012 · Hella Luksch, Michael J. Romanowski, et al. · Human Mutation · 37
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Non-canonical Caspase-1 Signaling Drives RIP2-Dependent and TNF-α-Mediated Inflammation In Vivo
2020 · Sören Reinke, Mary Linge, et al. · Cell Reports · 33
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cAMP Response Element Modulator α Induces Dual Specificity Protein Phosphatase 4 to Promote Effector T Cells in Juvenile-Onset Lupus
2019 · Sigrun R Hofmann, Katrin Mäbert, et al. · The Journal of Immunology · 33
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DNA methylation patterns in CD4+ T-cells separate psoriasis patients from healthy controls, and skin psoriasis from psoriatic arthritis
2023 · Valentina Natoli, Amandine Charras, et al. · Frontiers in Immunology · 32
Characterization and Analysis of the Proximal Janus Kinase 3 Promoter
2003 · Martin Aringer, Sigrun R Hofmann, et al. · The Journal of Immunology · 31
Human Procaspase-1 Variants with Decreased Enzymatic Activity Are Associated with Febrile Episodes and May Contribute to Inflammation via RIP2 and NF-κB Signaling
2014 · Michael C Heymann, Stefan Winkler, et al. · The Journal of Immunology · 27
DNA Methylation Patterns in CD8+ T Cells Discern Psoriasis From Psoriatic Arthritis and Correlate With Cutaneous Disease Activity
2021 · Amandine Charras, Jessica Garau, et al. · Frontiers in Cell and Developmental Biology · 25
P2RX7 gene variants associate with altered inflammasome assembly and reduced pyroptosis in chronic nonbacterial osteomyelitis (CNO)
2024 · Amandine Charras, Sigrun R. Hofmann, et al. · Journal of Autoimmunity · 24
Congenital Idiopathic Dilatation of the Right Atrium: Antenatal Appearance, Postnatal Management, Long-Term Follow-Up and Possible Pathomechanism
2012 · Sigrun R. Hofmann, Antje Heilmann, et al. · Fetal Diagnosis and Therapy · 23
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Cytohesin Binder and Regulator (Cybr) Is Not Essential for T- and Dendritic-Cell Activation and Differentiation
2006 · Wendy T. Watford, Denise Li, et al. · Molecular and Cellular Biology · 22
Dynamic CpG-DNA Methylation of Il10 and Il19 in CD4+ T Lymphocytes and Macrophages: Effects on Tissue-Specific Gene Expression
2011 · S. Hofmann, J. Möller, et al. · Klinische Pädiatrie · 21
Enzymatically Inactive Procaspase 1 stabilizes the ASC Pyroptosome and Supports Pyroptosome Spreading during Cell Division
2016 · Robert Stein, Franz Kapplusch, et al. · Journal of Biological Chemistry · 15
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Works count: 51
Citation count: 1,987
H-index: 22
I10-index: 27
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