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Claire Delehouzé

Observed names: C Delehouzé, C. Delehouze, C. Delehouzé, Claire Delehouze, Claire Delehouzé, Delehouze, Claire, Delehouzé, Claire, Delehouzé, Claire
Observed institutions: Centre National de la Recherche Scientifique, Station Biologique de Roscoff, Sorbonne Université, Laboratoire de Biologie Intégrative des Modèles Marins, ManRos Therapeutics (France), Phosphorylation de protéines et Pathologies Humaines, Université Pierre-et-Marie-Curie
ORCID: 0000-0003-4114-3051
Observed ORCID: 0000-0003-4114-3051
OpenAlex ID: A5017583905
CDK Inhibitors Roscovitine and CR8 Trigger Mcl-1 Down-Regulation and Apoptotic Cell Death in Neuroblastoma Cells
2010 · K. Bettayeb, D. Baunbaek, et al. · Genes & Cancer · 87
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CDK/CK1 inhibitors roscovitine and CR8 downregulate amplified MYCN in neuroblastoma cells
2013 · C Delehouzé, K Godl, et al. · Oncogene · 69
6E11, a highly selective inhibitor of Receptor-Interacting Protein Kinase 1, protects cells against cold hypoxia-reoxygenation injury
2017 · C. Delehouzé, S. Leverrier-Penna, et al. · Scientific Reports · 39
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Synthesis, biological evaluation and molecular modeling studies of imidazo[1,2- a ]pyridines derivatives as protein kinase inhibitors
2016 · Marie Lawson, Jordi Rodrigo, et al. · European Journal of Medicinal Chemistry · 35
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Sibiriline, a new small chemical inhibitor of receptor‐interacting protein kinase 1, prevents immune‐dependent hepatitis
2017 · Fabienne Le Cann, Claire Delehouzé, et al. · FEBS Journal · 30
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Development of new highly potent imidazo[1,2-b]pyridazines targeting Toxoplasma gondii calcium-dependent protein kinase 1
2015 · Espérance Moine, Isabelle Dimier-Poisson, et al. · European Journal of Medicinal Chemistry · 30
Betulin, a Newly Characterized Compound in Acacia auriculiformis Bark, Is a Multi-Target Protein Kinase Inhibitor
2021 · Augustine A. Ahmadu, Claire Delehouzé, et al. · Molecules · 25
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Nigratine as dual inhibitor of necroptosis and ferroptosis regulated cell death
2022 · Claire Delehouzé, Arnaud Comte, et al. · Scientific Reports · 24
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Discovery of simplified benzazole fragments derived from the marine benzosceptrin B as necroptosis inhibitors involving the receptor interacting protein Kinase-1
2020 · Mohamed Benchekroun, Ludmila Ermolenko, et al. · European Journal of Medicinal Chemistry · 17
Microwave synthesis of new 3-(3-aminopropyl)-5-arylidene- 2-thioxo-1,3-thiazolidine-4-ones as potential Ser/Thr protein kinase inhibitors
2016 · Christelle N’ta Ambeu, Camille Déliko Dago, et al. · Medicinal Chemistry Research · 11
Kinase-Based Screening of Marine Natural Extracts Leads to the Identification of a Cytotoxic High Molecular Weight Metabolite from the Mediterranean Sponge Crambe tailliezi
2019 · Thi-Ngoc-Dung Nguyen, Omid Feizbakhsh, et al. · Marine Drugs · 9
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Neurymenolide A, a Novel Mitotic Spindle Poison from the New Caledonian Rhodophyta Phacelocarpus neurymenioides
2019 · Sofia-Eléna Motuhi, Omid Feizbakhsh, et al. · Marine Drugs · 8
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A Transversal Approach Combining In Silico, In Vitro and In Vivo Models to Describe the Metabolism of the Receptor Interacting Protein 1 Kinase Inhibitor Sibiriline
2022 · Romain Pelletier, Thomas Gicquel, et al. · Pharmaceutics · 7
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Casein kinase 1ε and 1α as novel players in polycystic kidney disease and mechanistic targets for (R)-roscovitine and (S)-CR8
2018 · Katy Billot, Charlène Coquil, et al. · American Journal of Physiology-Renal Physiology · 7
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Sibiriline, a novel dual inhibitor of necroptosis and ferroptosis, prevents RIPK1 kinase activity and (phospho)lipid peroxidation as a potential therapeutic strategy
2025 · Claire Delehouzé, Melodie Mallais, et al. · Cell Death Discovery · 3
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NecroFerrins as dual therapeutic inhibitors targeting necroptosis and ferroptosis
2026 · Claire Delehouzé, Stéphane Bach · Ferroptosis and Oxidative Stress
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Sibiriline, an inhibitor of regulated necrosis, protects mice against Acetaminophen-induced liver injury, alone or in combination with N-acetyl-cysteine
2024 · Eugenio, Melanie Simoes, Imerzoukene, Ghiles, et al. · HAL (Le Centre pour la Communication Scientifique Directe)
FRI-333 Sibiriline, an inhibitor of regulated necrosis, protects mice against Acetaminophen-induced liver injury, alone or in combination with N-acetyl-cysteine
2024 · Mélanie Simoes Eugenio, Ghiles Imerzoukene, et al. · Journal of Hepatology
Chemobiological approach for studying the molecular modulation of regulated cell necrosis
2023 · Delehouzé, Claire · theses.fr (ABES)
Approche chémobiologique d’étude de la régulation moléculaire de la mort cellulaire programmée par nécrose pour l’optimisation de nouveaux candidats médicaments
2023 · Claire Delehouzé
Natural Product Derivatives For Inhibiting Cellular Necroptosis, Ferroptosis And Oxytosis
2022 · Bach, Stéphane, Dimanche-Boitrel, Marie-Thérèse, et al. · HAL (Le Centre pour la Communication Scientifique Directe)
Nigratine as first-in-class dual inhibitor of necroptosis and ferroptosis regulated cell death
2020 · Claire Delehouzé, Arnaud Comte, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Sibiriline derivatives for use for preventing and/or treating disorders associated with cellular necroptosis.
2017 · Dimanche-Boitrel, Marie-Thérèse, Bach, Stéphane, et al. · HAL (Le Centre pour la Communication Scientifique Directe)
N1- and N7-substituted sibiriline derivatives and their use as inhibitor of cellular necroptosis.
2017 · Dimanche-Boitrel, Marie-Thérèse, Bach, Stéphane, et al. · HAL (Le Centre pour la Communication Scientifique Directe)
Développement de nouveaux inhibiteurs de TgCDPK1 à visée anti-toxoplasmique
2016 · Moine, Espérance, Dimier-Poisson, Isabelle, et al. · HAL (Le Centre pour la Communication Scientifique Directe)
Works count: 26
Citation count: 401
H-index: 10
I10-index: 10
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