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Author

Andrew C. Hedman

Observed names: Andrew C Hedman, Andrew Hedman, Andrew C. Hedman
ORCID: 0009-0009-7704-7425
Observed ORCID: 0009-0009-7704-7425
OpenAlex ID: A5017586422
The biology of IQGAP proteins: beyond the cytoskeleton
2015 · Andrew C Hedman, Jessica M Smith, et al. · EMBO Reports · 240
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IQGAPs choreograph cellular signaling from the membrane to the nucleus
2015 · Jessica M. Smith, Andrew C. Hedman, et al. · Trends in Cell Biology · 176
Agonist-stimulated phosphatidylinositol-3,4,5-trisphosphate generation by scaffolded phosphoinositide kinases
2016 · Suyong Choi, Andrew C. Hedman, et al. · Nature Cell Biology · 130
Phosphatidylinositol 4,5‐bisphosphate: Targeted production and signaling
2013 · Yue Sun, Narendra Thapa, et al. · BioEssays · 106
LAPTM4B is a PtdIns(4,5)P2 effector that regulates EGFR signaling, lysosomal sorting, and degradation
2015 · Xiaojun Tan, Yue Sun, et al. · The EMBO Journal · 89
Endosomal Type Iγ PIP 5-Kinase Controls EGF Receptor Lysosomal Sorting
2013 · Yue Sun, Andrew C. Hedman, et al. · Developmental Cell · 82
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PIP kinases define PI4,5P2 signaling specificity by association with effectors
2015 · Suyong Choi, Narendra Thapa, et al. · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 75
IQGAP1 is a novel phosphatidylinositol 4,5 bisphosphate effector in regulation of directional cell migration
2013 · Suyong Choi, Narendra Thapa, et al. · The EMBO Journal · 64
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The IQGAP scaffolds: Critical nodes bridging receptor activation to cellular signaling
2023 · Louise Thines, Francis J. Roushar, et al. · The Journal of Cell Biology · 49
IQGAP1 Binds to Yes-associated Protein (YAP) and Modulates Its Transcriptional Activity
2016 · Samar Sayedyahossein, Zhigang Li, et al. · Journal of Biological Chemistry · 44
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Absence of IQGAP1 Protein Leads to Insulin Resistance
2017 · Bhavna Chawla, Andrew C. Hedman, et al. · Journal of Biological Chemistry · 33
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PIP Kinases from the Cell Membrane to the Nucleus
2012 · Mark Schramp, Andrew Hedman, et al. · Sub-cellular biochemistry/Subcellular biochemistry · 27
IQGAP1 binds AMPK and is required for maximum AMPK activation
2020 · Andrew C. Hedman, Zhigang Li, et al. · Journal of Biological Chemistry · 26
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Ubiquitination of the scaffold protein IQGAP1 diminishes its interaction with and activation of the Rho GTPase CDC42
2020 · Laëtitia Gorisse, Zhigang Li, et al. · Journal of Biological Chemistry · 26
PIPKIγi5 regulates the endosomal trafficking and degradation of E-cadherin
2014 · Nicholas J. Schill, Andrew C. Hedman, et al. · Journal of Cell Science · 26
Calmodulin Lobes Facilitate Dimerization and Activation of Estrogen Receptor-α
2017 · Zhigang Li, Yonghong Zhang, et al. · Journal of Biological Chemistry · 23
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Endogenous IQGAP1 and IQGAP3 do not functionally interact with Ras
2019 · Chase J. Morgan, Andrew C. Hedman, et al. · Scientific Reports · 19
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Ca2+-Dependent Switch of Calmodulin Interaction Mode with Tandem IQ Motifs in the Scaffolding Protein IQGAP1
2019 · Mingzhen Zhang, Zhigang Li, et al. · Biochemistry · 14
Phosphatidylinositol Phosphate 5-Kinase Iγi2 in Association with Src Controls Anchorage-independent Growth of Tumor Cells
2013 · Narendra Thapa, Suyong Choi, et al. · Journal of Biological Chemistry · 14
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Tyrosine phosphorylation of the scaffold protein IQGAP1 in the MET pathway alters function
2020 · Andrew C. Hedman, Dean E. McNulty, et al. · Journal of Biological Chemistry · 8
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Insulin suppresses transcriptional activity of yes-associated protein in insulin target cells
2019 · Samar Sayedyahossein, Andrew C. Hedman, et al. · Molecular Biology of the Cell · 8
IQGAP1 binds the Axl receptor kinase and inhibits its signaling
2018 · Laëtitia Gorisse, Zhigang Li, et al. · Biochemical Journal · 7
An unexpected role for PI4,5P2in EGF receptor endosomal trafficking
2013 · Yue Sun, Andrew C. Hedman, et al. · Cell Cycle · 5
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Molecular and Functional Diversities of Cadherin and Protocadherin
2010 · Kenichi Yoshida, Takeshi Noda, et al. · 5
Targeted protein degradation in lysosome utilizing naturally produced bifunctional antibodies with high levels of mannose 6-phosphate glycans
2024 · Andrew C. Hedman, Shou Liu, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
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Works count: 40
Citation count: 1,299
H-index: 17
I10-index: 19
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