Get started
Author

Jherek Swanger

ORCID: 0000-0001-7796-5511
Observed ORCID: 0000-0001-7796-5511
OpenAlex ID: A5017764964
Proteasomal Turnover of p21Cip1 Does Not Require p21Cip1 Ubiquitination
2000 · Robert J Sheaff, Jeffrey D Singer, et al. · Molecular Cell · 382
PDF
Kinase-Independent Function of Cyclin E
2007 · Yan Geng, Young-Mi Lee, et al. · Molecular Cell · 187
PDF
p53 and p21 Form an Inducible Barrier that Protects Cells against Cyclin E-cdk2 Deregulation
2002 · Alex C. Minella, Jherek Swanger, et al. · Current Biology · 117
PDF
Isoform- and cell cycle–dependent substrate degradation by the Fbw7 ubiquitin ligase
2008 · Jonathan E. Grim, Michael P. Gustafson, et al. · The Journal of Cell Biology · 116
PDF
The SCF–Fbw7 ubiquitin ligase degrades MED13 and MED13L and regulates CDK8 module association with Mediator
2013 · Michael A. Davis, Elizabeth A. Larimore, et al. · Genes & Development · 115
PDF
Characterization and Targeted Disruption of Murine Nup50, a p27Kip1-Interacting Component of the Nuclear Pore Complex
2000 · Matthew Smitherman, Keesook Lee, et al. · Molecular and Cellular Biology · 111
Fbw7 and p53 Cooperatively Suppress Advanced and Chromosomally Unstable Intestinal Cancer
2012 · Jonathan E. Grim, Sue E. Knoblaugh, et al. · Molecular and Cellular Biology · 97
Fbw7 dimerization determines the specificity and robustness of substrate degradation
2013 · Markus Welcker, Elizabeth A. Larimore, et al. · Genes & Development · 93
PDF
Phosphorylation of Eukaryotic Elongation Factor 2 (eEF2) by Cyclin A–Cyclin-Dependent Kinase 2 Regulates Its Inhibition by eEF2 Kinase
2012 · Asli A. Hizli, Yong Chi, et al. · Molecular and Cellular Biology · 77
PDF
Essential role for Cdk2 inhibitory phosphorylation during replication stress revealed by a human Cdk2 knockin mutation
2013 · Bridget T. Hughes, Julia Sidorova, et al. · Proceedings of the National Academy of Sciences · 76
Two diphosphorylated degrons control c-Myc degradation by the Fbw7 tumor suppressor
2022 · Markus Welcker, Baiyun Wang, et al. · Science Advances · 58
Pan-cancer transcriptional signatures predictive of oncogenic mutations reveal that Fbw7 regulates cancer cell oxidative metabolism
2018 · Ryan J. Davis, Mehmet Gönen, et al. · Proceedings of the National Academy of Sciences · 43
A novel landscape of nuclear human CDK2 substrates revealed by in situ phosphorylation
2020 · Yong Chi, John H. Carter, et al. · Science Advances · 41
PDF
FOXM1 drives HPV+ HNSCC sensitivity to WEE1 inhibition
2020 · Ahmed Diab, Hakan Gem, et al. · Proceedings of the National Academy of Sciences · 33
The PP2A-B56 Phosphatase Opposes Cyclin E Autocatalytic Degradation via Site-Specific Dephosphorylation
2017 · Ryan J. Davis, Jherek Swanger, et al. · Molecular and Cellular Biology · 15
Therapeutic scheduling of WEE1 inhibition preserves T cell function and promotes immune control of HPV⁺ tumors
2026 · Ying Liu, Zhiheng Zhang, et al. · bioRxiv (Cold Spring Harbor Laboratory)
PDF
1421 WEE1 inhibition triggers tumor microenvironment-dependent antitumor immunity against HPV+ HNSCC tumors
2024 · Ahmed Diab, Yasser Hussaini, et al. · Regular and Young Investigator Award Abstracts
Author response: Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations
2022 · H Nayanga Thirimanne, Feinan Wu, et al. · eLife
Abstract PR07: WEE1 inhibition triggers premature mitotic entry in HPV16-E6-expressing cells independent of p53 inactivation
2020 · Ahmed Diab, Jherek Swanger, et al. · Clinical Cancer Research
Abstract 308: The PP2A-B56 phosphatase opposes cyclin E autocatalytic degradation via site-specific dephosphorylation
2017 · Ryan J. Davis, Jherek Swanger, et al. · Cancer Research
Abstract 1340: A mouse model of metastatic intestinal cancers associated with Fbw7- and p53-loss
2012 · Jonathan E. Grim, Sue Knoblaugh, et al. · Cancer Research
A Novel Function for Cyclin E in Cell Cycle Progression
2007 · Yan Geng, Youngmi Lee, et al. · Springer eBooks
Works count: 28
Citation count: 1,561
H-index: 15
I10-index: 15
Year
Topic
Type