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Daisuke Sugiura

LAG-3: from molecular functions to clinical applications
2020 · Takumi Maruhashi, Daisuke Sugiura, et al. · Journal for ImmunoTherapy of Cancer · 475
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Restriction of PD-1 function by cis -PD-L1/CD80 interactions is required for optimal T cell responses
2019 · Daisuke Sugiura, Takumi Maruhashi, et al. · Science · 393
PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice
2011 · Taku Okazaki, Il-mi Okazaki, et al. · The Journal of Experimental Medicine · 339
LAG-3 inhibits the activation of CD4+ T cells that recognize stable pMHCII through its conformation-dependent recognition of pMHCII
2018 · Takumi Maruhashi, Il-mi Okazaki, et al. · Nature Immunology · 277
Binding of LAG-3 to stable peptide-MHC class II limits T cell function and suppresses autoimmunity and anti-cancer immunity
2022 · Takumi Maruhashi, Daisuke Sugiura, et al. · Immunity · 223
PD-1 Primarily Targets TCR Signal in the Inhibition of Functional T Cell Activation
2019 · Reina Mizuno, Daisuke Sugiura, et al. · Frontiers in Immunology · 186
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Atypical motifs in the cytoplasmic region of the inhibitory immune co-receptor LAG-3 inhibit T cell activation
2019 · Takeo K. Maeda, Daisuke Sugiura, et al. · Journal of Biological Chemistry · 120
PD-1 agonism by anti-CD80 inhibits T cell activation and alleviates autoimmunity
2022 · Daisuke Sugiura, Il-mi Okazaki, et al. · Nature Immunology · 102
Distribution and Function of Macrophage Galactose-type C-type Lectin 2 (MGL2/CD301b)
2010 · Kaori Denda-Nagai, Satoshi Aida, et al. · Journal of Biological Chemistry · 95
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PD-1 Imposes Qualitative Control of Cellular Transcriptomes in Response to T Cell Activation
2020 · Kenji Shimizu, Daisuke Sugiura, et al. · Molecular Cell · 64
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Glucocorticoids potentiate the inhibitory capacity of programmed cell death 1 by up-regulating its expression on T cells
2019 · Natsumi Maeda, Takumi Maruhashi, et al. · Journal of Biological Chemistry · 49
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Mucin 21/Epiglycanin Modulates Cell Adhesion
2010 · Yuri Yi, Mika Kamata-Sakurai, et al. · Journal of Biological Chemistry · 36
PD-1 preferentially inhibits the activation of low-affinity T cells
2021 · Kenji Shimizu, Daisuke Sugiura, et al. · Proceedings of the National Academy of Sciences · 27
PD-1 aborts the activation trajectory of autoreactive CD8+ T cells to prohibit their acquisition of effector functions
2019 · Hikari Okamura, Il-mi Okazaki, et al. · Journal of Autoimmunity · 20
T-cell-intrinsic and -extrinsic regulation of PD-1 function
2021 · Daisuke Sugiura, Kenji Shimizu, et al. · International Immunology · 17
Differential effector mechanisms induced by vaccination with MUC1 DNA in the rejection of colon carcinoma growth at orthotopic sites and metastases
2008 · Daisuke Sugiura, Satoshi Aida, et al. · Cancer Science · 17
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PD-1 efficiently inhibits T cell activation even in the presence of co-stimulation through CD27 and GITR
2019 · Reina Mizuno, Takumi Maruhashi, et al. · Biochemical and Biophysical Research Communications · 9
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Prevention of Inflammation-Driven Colon Carcinogenesis in Human MUC1 Transgenic Mice by Vaccination with MUC1 DNA and Dendritic Cells
2023 · Retno Murwanti, Kaori Denda-Nagai, et al. · Cancers · 7
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Local Effects of Regulatory T Cells in MUC1 Transgenic Mice Potentiate Growth of MUC1 Expressing Tumor Cells In Vivo
2012 · Daisuke Sugiura, Kaori Denda-Nagai, et al. · PLoS ONE · 5
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Organ microenvironment plays significant roles through Fas ligand in vaccine‐induced CD4+ T cell dependent suppression of tumor growth at the orthotopic site
2010 · Daisuke Sugiura, Kaori Denda‐Nagai, et al. · Cancer Science · 1
Establishment and maintenance of immune tolerance by immuno-inhibitory receptors
2016 · Takumi Maruhashi, Il‐mi Okazaki, et al. · The Molecular Biology Society of Japan
Works count: 21
Citation count: 2,462
H-index: 16
I10-index: 16
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