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R. Overman

Observed names: R. C. Overman, R.C. Overman, Ross C. Overman, Ross Overman, Ross Overmann, Ross C. Overman
ORCID: 0000-0001-8729-9735
Observed ORCID: 0000-0001-8729-9735
OpenAlex ID: A5017986639
Rapid isolation and enrichment of extracellular vesicle preparations using anion exchange chromatography
2018 · Nikki Heath, Lois Grant, et al. · Scientific Reports · 189
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Small Molecule Binding Sites on the Ras:SOS Complex Can Be Exploited for Inhibition of Ras Activation
2015 · Jon J. G. Winter, Malcolm Anderson, et al. · Journal of Medicinal Chemistry · 119
Structural Insights into FGFR Kinase Isoform Selectivity: Diverse Binding Modes of AZD4547 and Ponatinib in Complex with FGFR1 and FGFR4
2014 · Julie A. Tucker, Tobias Klein, et al. · Structure · 116
Engineered Cas9 extracellular vesicles as a novel gene editing tool
2022 · Xabier Osteikoetxea, Andreia Silva, et al. · Journal of Extracellular Vesicles · 113
Structural and functional characterization of a DARPin which inhibits Ras nucleotide exchange
2017 · Sandrine Guillard, Paulina Kolasinska-Zwierz, et al. · Nature Communications · 102
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KRAS-specific inhibition using a DARPin binding to a site in the allosteric lobe
2019 · Nicolas Bery, Sandrine Legg, et al. · Nature Communications · 97
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Structural basis of Lewis b antigen binding by the Helicobacter pylori adhesin BabA
2015 · Naim Hage, Tina Howard, et al. · Science Advances · 92
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Endosomal Escape Enhancing Compounds Facilitate Functional Delivery of Extracellular Vesicle Cargo
2019 · Nikki Heath, Xabier Osteikoetxea, et al. · Nanomedicine · 79
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Discovery of N-(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)-1H-1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors
2018 · Jason G. Kettle, Rana Anjum, et al. · Journal of Medicinal Chemistry · 71
Plant‐made dengue virus‐like particles produced by co‐expression of structural and non‐structural proteins induce a humoral immune response in mice
2020 · Daniel Ponndorf, Yulia Meshcheriakova, et al. · Plant Biotechnology Journal · 54
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Recurrent MLK4 Loss-of-Function Mutations Suppress JNK Signaling to Promote Colon Tumorigenesis
2015 · Anna A. Marusiak, Natalie L. Stephenson, et al. · Cancer Research · 49
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Development of Specific, Irreversible Inhibitors for a Receptor Tyrosine Kinase EphB3
2016 · Alvin Kung, Ying-Chu Chen, et al. · Journal of the American Chemical Society · 35
Discovery and pharmacological characterization of AZD3229, a potent KIT/PDGFRα inhibitor for treatment of gastrointestinal stromal tumors
2020 · Erica Banks, Michael Grondine, et al. · Science Translational Medicine · 30
The structure of human GCN2 reveals a parallel, back-to-back kinase dimer with a plastic DFG activation loop motif
2020 · Taiana Maia de Oliveira, Victoria Korboukh, et al. · Biochemical Journal · 29
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Generating Selective Leads for Mer Kinase Inhibitors—Example of a Comprehensive Lead-Generation Strategy
2021 · J. Willem M. Nissink, Sana Bazzaz, et al. · Journal of Medicinal Chemistry · 28
A-loop interactions in Mer tyrosine kinase give rise to inhibitors with two-step mechanism and long residence time of binding
2020 · Alexander Pflug, Marianne Schimpl, et al. · Biochemical Journal · 25
Completing the structural family portrait of the human EphB tyrosine kinase domains
2014 · Ross C. Overman, Judit E. Debreczeni, et al. · Protein Science · 25
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A Chemical-Genetic Approach to Generate Selective Covalent Inhibitors of Protein Kinases
2017 · Alvin Kung, Marianne Schimpl, et al. · ACS Chemical Biology · 18
Quantitative investigation of the affinity of human respiratory syncytial virus phosphoprotein C-terminus binding to nucleocapsid protein
2014 · Adam B Shapiro, Ning Gao, et al. · Virology Journal · 16
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Structural and binding characterization of the LacdiNAc-specific adhesin (LabA; HopD) exodomain from Helicobacter pylori
2020 · Vasiliki Paraskevopoulou, Marianne Schimpl, et al. · Current Research in Structural Biology · 10
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Introduction of a C-terminal hexa-lysine tag increases thermal stability of the LacDiNac binding adhesin (LabA) exodomain from Helicobacter pylori
2019 · Vasiliki Paraskevopoulou, Verónica García Artiaga, et al. · Protein Expression and Purification · 8
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Biochemical and biophysical characterization of four EphB kinase domains reveals contrasting thermodynamic, kinetic and inhibition profiles
2013 · Ross C. Overman, Judit E. Debreczeni, et al. · Bioscience Reports · 8
Affimer reagents enable targeted delivery of therapeutic agents and RNA via virus-like particles
2024 · Sophie E. Roberts, Heather L. Martin, et al. · iScience · 4
Stability and solubility engineering of the EphB4 tyrosine kinase catalytic domain using a rationally designed synthetic library
2013 · R. C. Overman, I. Green, et al. · Protein Engineering Design and Selection · 2
Data from Recurrent MLK4 Loss-of-Function Mutations Suppress JNK Signaling to Promote Colon Tumorigenesis
2023 · Anna A. Marusiak, Natalie L. Stephenson, et al.
Works count: 51
Citation count: 1,320
H-index: 18
I10-index: 20
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