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Robert Kastelein
Observed names:
Kastelein, Robert; id_orcid 0000-0002-7318-6884,
R Kastelein,
R. Kastelein,
Robert A Kastelein
Institution:
Synthekine
Observed institutions:
Merck & Co., Inc., Rahway, NJ, USA (United States),
Leiden University Medical Center,
Royal Tropical Institute,
Synthekine
ORCID:
0000-0002-7318-6884
Observed ORCID:
0000-0002-7318-6884
OpenAlex ID:
A5018250332
Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteria
2004
·
Frank A. W. Verreck
, Tjitske de Boer
, et al.
·
Proceedings of the National Academy of Sciences
·
1,012
Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of haematopoietic stem cells and is encoded by variant RNAs
1994
·
C. Hannum
, J. Culpepper
, et al.
·
Nature
·
442
Modulation of murine macrophage function by IL-13.
1993
·
T M Doherty
, R Kastelein
, et al.
·
The Journal of Immunology
·
245
Cutting Edge: A Critical Functional Role for IL-23 in Psoriasis
2010
·
Giulia Tonel
, Curdin Conrad
, et al.
·
The Journal of Immunology
·
228
IL-27 Mediates Complete Regression of Orthotopic Primary and Metastatic Murine Neuroblastoma Tumors: Role for CD8+ T Cells
2004
·
Rosalba Salcedo
, Jimmy K Stauffer
, et al.
·
The Journal of Immunology
·
163
Mouse T Cell Membrane Proteins Rt6−1 and Rt6−2 Are Arginine/Protein Mono(ADPribosyl)transferases and Share Secondary Structure Motifs with ADP-ribosylating Bacterial Toxins
1996
·
Friedrich Koch-Nolte
, David Petersen
, et al.
·
Journal of Biological Chemistry
·
137
PDF
Interleukin-18 (IL-18) Enhances Innate IL-12-Mediated Resistance toToxoplasma gondii
2000
·
Guifang Cai
, Robert Kastelein
, et al.
·
Infection and Immunity
·
116
Molecular cloning of a cDNA encoding the human interleukin 4 receptor
1990
·
Jean-Pierre Galizzl
, Caroline E. Zuber
, et al.
·
International Immunology
·
116
Immunologic and Therapeutic Synergy of IL-27 and IL-2: Enhancement of T Cell Sensitization, Tumor-Specific CTL Reactivity and Complete Regression of Disseminated Neuroblastoma Metastases in the Liver and Bone Marrow
2009
·
Rosalba Salcedo
, Julie A Hixon
, et al.
·
The Journal of Immunology
·
101
Identification of STAT4-Dependent and Independent Mechanisms of Resistance to Toxoplasma gondii
2000
·
Guifang Cai
, Thad Radzanowski
, et al.
·
The Journal of Immunology
·
98
PDF
FLK-2/FLT-3 ligand regulates the growth of early myeloid progenitors isolated from human fetal liver
1995
·
MO Muench
, MG Roncarolo
, et al.
·
Blood
·
94
Signaling Events Involved in Interleukin 27 (IL-27)-induced Proliferation of Human Naive CD4+ T Cells and B Cells
2011
·
Pascaline Charlot-Rabiega
, Emilie Bardel
, et al.
·
Journal of Biological Chemistry
·
43
PDF
Uncovered: the family relationship of a T-cell-membrane protein and bacterial toxins
1996
·
Friedrieh Koch-Nolte
, Friedrich Haag
, et al.
·
Immunology Today
·
35
Circulating and Gut-resident Human Th17 Cells Express CD161 and Promote Intestinal Inflammation
2009
·
Melanie Kleinschek
, Katia Boniface
, et al.
·
Clinical Immunology
·
33
Expression of biologically active, mature human granulocyte-macrophage colony stimulating factor with anE. coli secretory expression system
1988
·
Robert Greenberg
, Daniel Lundell
, et al.
·
Current Microbiology
·
17
Evaluation of murine interleukin 4 (IL-4) receptor expression using anti-receptor monoclonal antibodies and S1 nuclease protection analyses
1991
·
Hiroshi Ishida
, Gloria Yang
, et al.
·
Cellular Immunology
·
4
How Taxes of Local Governments Can Contribute to Climate Goals
2022
·
Arjen Schep
, Anneke Monsma
, et al.
·
Erasmus Law Review
·
3
PDF
Abstract 5544: IL10/IL2 surrogate cytokine agonists
2022
·
Mahalakshmi Ramadass
, Sandro Vivona
, et al.
·
Cancer Research
·
2
New paradigms in inflammation: where to next?
2008
·
Christopher A. Hunter
, Robert Kastelein
·
Immunological Reviews
·
2
1053 Preclinical pharmacodynamic characterization of STK-026: a novel IL-12 partial agonist for cancer with maintained CD8 T cell activity, reduced NK-mediated toxicity and an improved therapeutic window
2023
·
Zhenya Koliesnik
, Michael Totagrande
, et al.
·
Journal for ImmunoTherapy of Cancer
·
1
PDF
Functional dissection of interleukin-17 in the pathogenesis of psoriasis
2007
·
Claudia Conrad
, G Tonel
, et al.
·
Research Portal (King's College London)
·
1
An IL-6 receptor antagonist for IL-6 activity on human myeloma cells
1994
·
J.P.J. Brakenhoff
, F.D. de Hon
, et al.
·
Cytokine
·
1
1041 Preferential stimulation of antigen activated CD25 + CD8 T cells with STK-012, an α/β biased IL-2, avoids capillary leak syndrome and enhances anti-tumor immunity
2026
·
In-Young E Jung
, Jan Emmerich
, et al.
·
Journal for ImmunoTherapy of Cancer
PDF
Verlengde beslistermijn gemeenten ook van toepassing op dwangsombeschikking.
2026
·
Kastelein, Robert; id_orcid 0000-0002-7318-6884
·
EUR Research Repository (Erasmus University Rotterdam)
Theorie en praktijk van de bufferfunctie van gemeentelijke belastingen
2026
·
Schep, Arjen; id_orcid 0000-0001-6993-2533
, Kastelein, Robert; id_orcid 0000-0002-7318-6884
·
EUR Research Repository (Erasmus University Rotterdam)
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Works count:
33
Citation count:
2,894
H-index:
15
I10-index:
15
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