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Wenjian Min

Observed name: Wen‐Jian Min
ORCID: 0000-0002-0519-0654
Observed ORCID: 0000-0002-0519-0654
OpenAlex ID: A5018320327
Selective inhibition of CDK4/6: A safe and effective strategy for developing anticancer drugs
2020 · Kai Yuan, Xiao Wang, et al. · Acta Pharmaceutica Sinica B · 143
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Tubeimoside-1 induces TFEB-dependent lysosomal degradation of PD-L1 and promotes antitumor immunity by targeting mTOR
2021 · Xiaojia Liu, Mingxiao Yin, et al. · Acta Pharmaceutica Sinica B · 85
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Serum‐plasma matched metabolomics for comprehensive characterization of benign thyroid nodule and papillary thyroid carcinoma
2018 · Feng‐Qing Huang, Jing Li, et al. · International Journal of Cancer · 52
Novel Small-Molecule PD-L1 Inhibitor Induces PD-L1 Internalization and Optimizes the Immune Microenvironment
2022 · Chengliang Sun, Mingxiao Yin, et al. · Journal of Medicinal Chemistry · 48
Design, Synthesis, and Biological Evaluation of Novel EGFR PROTACs Targeting C797S Mutation
2024 · Yasheng Zhu, Xiuquan Ye, et al. · Journal of Medicinal Chemistry · 40
A new LKB1 activator, piericidin analogue S14, retards renal fibrosis through promoting autophagy and mitochondrial homeostasis in renal tubular epithelial cells
2022 · Canzhen Liu, Xiaoxu Wang, et al. · Theranostics · 40
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Targeting ADAR1 with a small molecule for the treatment of prostate cancer
2025 · Xiao Wang, Jiaxing Li, et al. · Nature Cancer · 39
Novel phthalimides regulating PD-1/PD-L1 interaction as potential immunotherapy agents
2022 · Chengliang Sun, Yao Cheng, et al. · Acta Pharmaceutica Sinica B · 35
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B7-1 mediates podocyte injury and glomerulosclerosis through communication with Hsp90ab1-LRP5-β-catenin pathway
2022 · Jiemei Li, Jing Niu, et al. · Cell Death and Differentiation · 34
Discovery of Novel Fourth-Generation EGFR Inhibitors to Overcome C797S-Mediated Resistance
2023 · Yasheng Zhu, Xiuquan Ye, et al. · Journal of Medicinal Chemistry · 26
Development and clinical advancement of small molecules for ex vivo expansion of hematopoietic stem cell
2021 · Jiaxing Li, Xiao Wang, et al. · Acta Pharmaceutica Sinica B · 23
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Fibroblast expression of transmembrane protein smoothened governs microenvironment characteristics after acute kidney injury
2024 · Yuan Gui, Haiyan Fu, et al. · Journal of Clinical Investigation · 20
Targeting dual-specificity tyrosine phosphorylation-regulated kinase 2 with a highly selective inhibitor for the treatment of prostate cancer
2022 · Kai Yuan, Zhaoxing Li, et al. · Nature Communications · 19
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Design, Synthesis, and Antitumor Activity Evaluation of Novel VISTA Small Molecule Inhibitors
2024 · Chengliang Sun, Yuling He, et al. · Journal of Medicinal Chemistry · 18
Limonin, a natural ERK2 agonist, protects against ischemic acute kidney injury
2023 · Xianke Zhou, Yadie Xiang, et al. · International Journal of Biological Sciences · 18
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Sodium cantharidinate, a novel anti-pancreatic cancer agent that activates functional p53
2020 · Xiaoxiao Liu, Li Zhang, et al. · Science China Life Sciences · 18
Iron‐Catalyzed C(sp3)−C(sp3) Bond Formation in 3,4‐Dihydro‐1,4‐benzoxazin‐2‐ones
2017 · Jie Dong, Wenjian Min, et al. · Advanced Synthesis & Catalysis · 18
Discovery of Dual CDK6/PIM1 Inhibitors with a Novel Structure, High Potency, and Favorable Druggability for the Treatment of Acute Myeloid Leukemia
2021 · Kai Yuan, Minghui Ji, et al. · Journal of Medicinal Chemistry · 17
Discovery of Potent DYRK2 Inhibitors with High Selectivity, Great Solubility, and Excellent Safety Properties for the Treatment of Prostate Cancer
2023 · Kai Yuan, Hongtao Shen, et al. · Journal of Medicinal Chemistry · 16
Discovery, Optimization, and Evaluation of Selective CDK4/6 Inhibitors for the Treatment of Breast Cancer
2022 · Weijiao Chen, Minghui Ji, et al. · Journal of Medicinal Chemistry · 16
Discovery of novel and orally bioavailable CDK 4/6 inhibitors with high kinome selectivity, low toxicity and long-acting stability for the treatment of multiple myeloma
2021 · Kai Yuan, Wenbin Kuang, et al. · European Journal of Medicinal Chemistry · 16
Lead discovery, chemical optimization, and biological evaluation studies of novel histone methyltransferase SET7 small-molecule inhibitors
2020 · Zeng Hou, Wenjian Min, et al. · Bioorganic & Medicinal Chemistry Letters · 16
Discovery of Novel Phosphoinositide-3-Kinase α Inhibitors with High Selectivity, Excellent Bioavailability, and Long-Acting Efficacy for Gastric Cancer
2022 · Yi Hou, Fang Zhang, et al. · Journal of Medicinal Chemistry · 15
Discovery of Novel and Selective CDK4/6 Inhibitors By Pharmacophore and structure-based Virtual Screening
2020 · Kai Yuan, Wenjian Min, et al. · Future Medicinal Chemistry · 15
Discovery of Novel Small-Molecule Inhibitors Disrupting the MTDH-SND1 Protein–Protein Interaction
2025 · Hao Shen, Jiayu Ding, et al. · Journal of Medicinal Chemistry · 13
Works count: 51
Citation count: 919
H-index: 17
I10-index: 28
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