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Lailiang Qu

Observed names: Lai-Liang Qu, Qu, Lailiang
ORCID: 0009-0009-0886-6128
Observed ORCID: 0009-0009-0886-6128
OpenAlex ID: A5018654186
Discovery of First-in-Class Dual PARP and EZH2 Inhibitors for Triple-Negative Breast Cancer with Wild-Type BRCA
2021 · Cheng Wang, Lailiang Qu, et al. · Journal of Medicinal Chemistry · 109
Discovery of precision targeting EZH2 degraders for triple-negative breast cancer
2022 · Cheng Wang, Xinye Chen, et al. · European Journal of Medicinal Chemistry · 68
Discovery of PT-65 as a highly potent and selective Proteolysis-targeting chimera degrader of GSK3 for treating Alzheimer's disease
2021 · Lailiang Qu, Shang Li, et al. · European Journal of Medicinal Chemistry · 63
Design, Synthesis, and Antifungal Activities of Novel Pyrazole-4-carboxamide Derivatives Containing an Ether Group as Potential Succinate Dehydrogenase Inhibitors
2023 · Bo Luo, Yacong Zhao, et al. · Journal of Agricultural and Food Chemistry · 54
Novel insights into RIPK1 as a promising target for future Alzheimer’s disease treatment
2021 · Shang Li, Lailiang Qu, et al. · Pharmacology & Therapeutics · 51
Histone Deacetylase and Enhancer of Zeste Homologue 2 Dual Inhibitors Presenting a Synergistic Effect for the Treatment of Hematological Malignancies
2022 · Dehua Lu, Cheng Wang, et al. · Journal of Medicinal Chemistry · 47
Synthesis and evaluation of multi-target-directed ligands with BACE-1 inhibitory and Nrf2 agonist activities as potential agents against Alzheimer’s disease
2021 · Lailiang Qu, Limei Ji, et al. · European Journal of Medicinal Chemistry · 47
Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer
2021 · Xingchen Liu, Cheng Wang, et al. · Journal of Medicinal Chemistry · 36
Usnic acid derivatives as tau-aggregation and neuroinflammation inhibitors
2019 · Cun-Jian Shi, Wan Peng, et al. · European Journal of Medicinal Chemistry · 36
A hemicyanine derivative for near-infrared imaging of β-amyloid plaques in Alzheimer's disease
2019 · Hua-Li Yang, Si-Qiang Fang, et al. · European Journal of Medicinal Chemistry · 32
Dual roles of inflammatory programmed cell death in cancer: insights into pyroptosis and necroptosis
2024 · Shuai Wang, Huanhuan He, et al. · Frontiers in Pharmacology · 30
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Identification and optimization of piperlongumine analogues as potential antioxidant and anti-inflammatory agents via activation of Nrf2
2020 · Limei Ji, Lailiang Qu, et al. · European Journal of Medicinal Chemistry · 30
Optimization of WZ4003 as NUAK inhibitors against human colorectal cancer
2020 · Huali Yang, Xiaobing Wang, et al. · European Journal of Medicinal Chemistry · 29
Novel Pyrazole-4-Carboxamide Derivatives Containing Oxime Ether Group as Potential SDHIs to Control Rhizoctonia solani
2024 · Bo Luo, Yuerui Wu, et al. · Journal of Agricultural and Food Chemistry · 28
Iodine-catalyzed oxidative cyclisation for the synthesis of sarisan analogues containing 1,3,4-oxadiazole as insecticidal agents
2016 · Yong Guo, Lailiang Qu, et al. · RSC Advances · 28
Harmine-based dual inhibitors targeting histone deacetylase (HDAC) and DNA as a promising strategy for cancer therapy
2022 · Dehua Lu, Lailiang Qu, et al. · Bioorganic Chemistry · 25
Design, synthesis, antibacterial and insecticidal activities of novel N-phenylpyrazole fraxinellone hybrid compounds
2017 · Yong Guo, Xiaoguang Wang, et al. · RSC Advances · 23
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Application of Sustainable Natural Bioresources in Agriculture: Iodine-Mediated Oxidative Cyclization for Metal-Free One-Pot Synthesis of N -Phenylpyrazole Sarisan Analogues as Insecticidal Agents
2017 · Lailiang Qu, Hongyu Xu, et al. · ACS Omega · 16
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Design, synthesis, and antibacterial activity of novel 8-methoxyquinoline-2-carboxamide compounds containing 1,3,4-thiadiazole moiety
2017 · Tengfei Qu, Lailiang Qu, et al. · Zeitschrift für Naturforschung C · 14
Natural products as sources of new antioxidants: Synthesis and antioxidant evaluation of Mannich bases of novel sesamol derivatives
2019 · Yong Guo, Jiangping Fan, et al. · Industrial Crops and Products · 13
Novel pyrazole-4-carboxamides and aromatic carboxamides derivatives containing a hydrazine moiety as potential SDHIs
2023 · Bo Luo, Wei Zhou, et al. · Journal of Molecular Structure · 12
Design, Synthesis, and Antifungal Activities of Novel Carboxamides Derivatives Bearing a Chalcone Scaffold as Potential SDHIs
2023 · Bo Luo, Chongchong Zhang, et al. · Chemistry & Biodiversity · 11
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Rhodium( iii ) catalyzed olefination and deuteration of tetrahydrocarbazole
2021 · Wan Peng, Qiaohong Liu, et al. · RSC Advances · 11
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Identification of Astragalus Polysaccharide as a Neuroprotective Agent via Activating Klotho-mediated Nrf2 Pathway
2024 · Kuo Liu, Nannan Ding, et al. · Pharmacognosy Magazine · 4
Novel pyrazole-4-carboxamides containing a piperazine moiety: Synthesis, crystal structure, antifungal activity, molecular docking, DFT and ESP calculations
2025 · Bo Luo, Mengxing Liu, et al. · Journal of Molecular Structure · 3
Works count: 30
Citation count: 826
H-index: 17
I10-index: 23
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