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Derren J. Heyes

Observed names: D.J. Heyes, Derren Heyes, Derren J Heyes, Derren James Heyes, Derren J. Heyes, Derren J. Heyes, HEYES, Derren, Heyes Derren, Heyes, Derren, Heyes, Derren J, Heyes, Derren J., Heyes, Derren; id_orcid 0000-0002-7453-1571
Observed institutions: Engineering and Physical Sciences Research Council, Biotechnology and Biological Sciences Research Council, University of Manchester, Research Complex at Harwell, Central Laser Facility, Vrije Universiteit Amsterdam, University of Sheffield
ORCID: 0000-0002-7453-1571
Observed ORCID: 0000-0002-7453-1571
OpenAlex ID: A5018819443
A designed photoenzyme for enantioselective [2+2] cycloadditions
2022 · Jonathan S. Trimble, Rebecca Crawshaw, et al. · Nature · 247
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Quantum Biology: An Update and Perspective
2021 · Youngchan Kim, Federico Bertagna, et al. · Quantum Reports · 189
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Making light work of enzyme catalysis: protochlorophyllide oxidoreductase
2005 · Derren J. Heyes, C. Neil Hunter · Trends in Biochemical Sciences · 185
Light-induced structural changes in a full-length cyanobacterial phytochrome probed by time-resolved X-ray scattering
2018 · Derren J. Heyes, Samantha J. O. Hardman, et al. · Communications Biology · 172
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Structural basis for enzymatic photocatalysis in chlorophyll biosynthesis
2019 · Shaowei Zhang, Derren J. Heyes, et al. · Nature · 167
Conformational changes in an ultrafast light-driven enzyme determine catalytic activity
2008 · Olga A. Sytina, Derren J. Heyes, et al. · Nature · 144
Structural basis of kynurenine 3-monooxygenase inhibition
2013 · Marta Amaral, Colin Levy, et al. · Nature · 135
Photochemical Mechanism of Light-Driven Fatty Acid Photodecarboxylase
2020 · Derren J. Heyes, Balaji Lakavath, et al. · ACS Catalysis · 133
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Low carbon strategies for sustainable bio-alkane gas production and renewable energy
2020 · Mohamed Amer, Emilia Z. Wojcik, et al. · Energy & Environmental Science · 128
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Enzymatic Carboxylation of 2-Furoic Acid Yields 2,5-Furandicarboxylic Acid (FDCA)
2019 · Karl A.P. Payne, Stephen A. Marshall, et al. · ACS Catalysis · 125
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Catalytic Mechanism of Aromatic Nitration by Cytochrome P450 TxtE: Involvement of a Ferric-Peroxynitrite Intermediate
2020 · Savvas Louka, Sarah M. Barry, et al. · Journal of the American Chemical Society · 100
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Nuclear Quantum Tunneling in the Light-activated Enzyme Protochlorophyllide Oxidoreductase
2008 · Derren J. Heyes, Michiyo Sakuma, et al. · Journal of Biological Chemistry · 91
Catalytic Mechanism of Cofactor-Free Dioxygenases and How They Circumvent Spin-Forbidden Oxygenation of Their Substrates
2015 · Aitor Hernández-Ortega, Matthew G. Quesne, et al. · Journal of the American Chemical Society · 89
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Enzymology below 200 K: The kinetics and thermodynamics of the photochemistry catalyzed by protochlorophyllide oxidoreductase
2002 · Derren J. Heyes, Alexander V. Ruban, et al. · Proceedings of the National Academy of Sciences · 89
Insights into the H 2 O 2 ‐driven catalytic mechanism of fungal lytic polysaccharide monooxygenases
2021 · Tobias M. Hedison, Erik Breslmayr, et al. · FEBS Journal · 81
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Radical-based photoinactivation of fatty acid photodecarboxylases
2020 · Balaji Lakavath, Tobias M. Hedison, et al. · Analytical Biochemistry · 80
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Ultrafast enzymatic reaction dynamics in protochlorophyllide oxidoreductase
2003 · Derren J Heyes, C Neil Hunter, et al. · Nature Structural & Molecular Biology · 79
Proton-Coupled Electron Transfer in the Catalytic Cycle of Alcaligenes xylosoxidans Copper-Dependent Nitrite Reductase
2011 · Nicole G. H. Leferink, Cong Han, et al. · Biochemistry · 71
Protochlorophyllide Oxidoreductase: “Dark” Reactions of a Light-Driven Enzyme
2002 · Derren J. Heyes, Alexander V. Ruban, et al. · Biochemistry · 66
A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites
2019 · Shaowei Zhang, Michiyo Sakuma, et al. · Communications Biology · 65
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Light-driven biocatalytic reduction of α,β-unsaturated compounds by ene reductases employing transition metal complexes as photosensitizers
2015 · Martyn K. Peers, Helen S. Toogood, et al. · Catalysis Science & Technology · 63
The First Catalytic Step of the Light-driven Enzyme Protochlorophyllide Oxidoreductase Proceeds via a Charge Transfer Complex
2006 · Derren J. Heyes, Peter Heathcote, et al. · Journal of Biological Chemistry · 63
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Demonstration of Proton-coupled Electron Transfer in the Copper-containing Nitrite Reductases
2009 · Sibylle Brenner, Derren J. Heyes, et al. · Journal of Biological Chemistry · 57
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Efficient and selective energy transfer photoenzymes powered by visible light
2025 · Rebecca Crawshaw, Ross Smithson, et al. · Nature Chemistry · 56
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A guide to time‐resolved structural analysis of light‐activated proteins
2021 · Harshwardhan Poddar, Derren J. Heyes, et al. · FEBS Journal · 56
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Works count: 167
Citation count: 4,715
H-index: 37
I10-index: 97
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