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Zhengfan Jiang

Observed names: Jiang Zhengfan, Jiang, Zhengfan, Z F Jiang, Zheng-Fan Jiang, Zheng-fan Jiang, ZhengFan JIANG, Zheng‐Fan Jiang
Observed institutions: Scripps Research Institute, Cleveland Clinic, Shanghai Medical College of Fudan University, University of Toronto, Peking University, Fudan University, Shanghai Public Health Clinical Center, Athersys (United States), Center for Life Sciences, State Key Laboratory of Protein and Plant Gene Research, State Key Laboratory of Membrane Biology, Cleveland Clinic Research, The Ohio State University, Tsinghua University
ORCID: 0000-0002-1247-1382
Observed ORCID: 0000-0002-1247-1382
OpenAlex ID: A5018827487
Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy
2020 · Mengze Lv, Meixia Chen, et al. · Cell Research · 1,088
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Manganese Increases the Sensitivity of the cGAS-STING Pathway for Double-Stranded DNA and Is Required for the Host Defense against DNA Viruses
2018 · Chenguang Wang, Yukun Guan, et al. · Immunity · 881
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ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization
2009 · Wenxiang Sun, Yang Li, et al. · Proceedings of the National Academy of Sciences · 878
GENETIC ANALYSIS OF HOST RESISTANCE: Toll-Like Receptor Signaling and Immunity at Large
2006 · Bruce Beutler, Zhengfan Jiang, et al. · Annual Review of Immunology · 784
CD14 is required for MyD88-independent LPS signaling
2005 · Zhengfan Jiang, Philippe Georgel, et al. · Nature Immunology · 683
STING directly activates autophagy to tune the innate immune response
2018 · Dong Liu, Hao Wu, et al. · Cell Death and Differentiation · 439
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Toll-like receptor 3-mediated activation of NF-κB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-β
2004 · Zhengfan Jiang, Tak W. Mak, et al. · Proceedings of the National Academy of Sciences · 403
Activation of STAT6 by STING Is Critical for Antiviral Innate Immunity
2011 · Huihui Chen, Hui Sun, et al. · Cell · 383
Hypersusceptibility to Vesicular Stomatitis Virus Infection in Dicer1-Deficient Mice Is Due to Impaired miR24 and miR93 Expression
2007 · Motoyuki Otsuka, Qing Jing, et al. · Immunity · 371
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Apoptotic Caspases Suppress Type I Interferon Production via the Cleavage of cGAS, MAVS, and IRF3
2019 · Xiaohan Ning, Yutao Wang, et al. · Molecular Cell · 347
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PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4
2009 · Fuping You, Hui Sun, et al. · Nature Immunology · 341
Mn2+ Directly Activates cGAS and Structural Analysis Suggests Mn2+ Induces a Noncanonical Catalytic Synthesis of 2′3′-cGAMP
2020 · Zhen Zhao, Zhixing Ma, et al. · Cell Reports · 338
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Manganese salts function as potent adjuvants
2021 · Rui Zhang, Chenguang Wang, et al. · Cellular and Molecular Immunology · 329
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Metalloimmunology: The metal ion-controlled immunity
2019 · Chenguang Wang, Rui Zhang, et al. · Advances in immunology · 305
Poly(dI·dC)-induced Toll-like Receptor 3 (TLR3)-mediated Activation of NFκB and MAP Kinase Is through an Interleukin-1 Receptor-associated Kinase (IRAK)-independent Pathway Employing the Signaling Components TLR3-TRAF6-TAK1-TAB2-PKR
2003 · Zhengfan Jiang, Maryam Zamanian-Daryoush, et al. · Journal of Biological Chemistry · 300
Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity
2020 · Chun Zhou, Xia Chen, et al. · Immunity · 299
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Interleukin-1 (IL-1) Receptor-Associated Kinase-Dependent IL-1-Induced Signaling Complexes Phosphorylate TAK1 and TAB2 at the Plasma Membrane and Activate TAK1 in the Cytosol
2002 · Zhengfan Jiang, Jun Ninomiya-Tsuji, et al. · Molecular and Cellular Biology · 286
Inflammasome Activation Triggers Caspase-1-Mediated Cleavage of cGAS to Regulate Responses to DNA Virus Infection
2017 · Yutao Wang, Xiaohan Ning, et al. · Immunity · 279
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NEMO–IKKβ Are Essential for IRF3 and NF-κB Activation in the cGAS–STING Pathway
2017 · Run Fang, Chenguang Wang, et al. · The Journal of Immunology · 232
The structural basis for the sensing and binding of cyclic di-GMP by STING
2012 · Yi-He Huang, Xiang-Yu Liu, et al. · Nature Structural & Molecular Biology · 224
A Toll-Like Receptor 2-Responsive Lipid Effector Pathway Protects Mammals against Skin Infections with Gram-Positive Bacteria
2005 · Philippe Georgel, Karine Crozat, et al. · Infection and Immunity · 222
MAVS activates TBK1 and IKKε through TRAFs in NEMO dependent and independent manner
2017 · Run Fang, Qifei Jiang, et al. · PLoS Pathogens · 218
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Vesicular stomatitis virus glycoprotein G activates a specific antiviral Toll-like receptor 4-dependent pathway
2007 · Philippe Georgel, Zhengfan Jiang, et al. · Virology · 211
The STING phase-separator suppresses innate immune signalling
2021 · Xiaoyu Yu, Liyuan Zhang, et al. · Nature Cell Biology · 205
TRIM30α Is a Negative-Feedback Regulator of the Intracellular DNA and DNA Virus-Triggered Response by Targeting STING
2015 · Yanming Wang, Qiaoshi Lian, et al. · PLoS Pathogens · 198
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Works count: 124
Citation count: 14,370
H-index: 55
I10-index: 83
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