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Molly C. Madden

Observed name: Molly Madden
ORCID: 0009-0009-9008-7288
Observed ORCID: 0009-0009-9008-7288
OpenAlex ID: A5018840484
Myostatin, activin receptor IIb, and follistatin-like-3 gene expression are altered in adipose tissue and skeletal muscle of obese mice
2008 · David L. Allen, Allison S. Cleary, et al. · American Journal of Physiology-Endocrinology and Metabolism · 191
Acute daily psychological stress causes increased atrophic gene expression and myostatin-dependent muscle atrophy
2010 · David L. Allen, Gary E. McCall, et al. · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 55
Modulating fast skeletal muscle contraction protects skeletal muscle in animal models of Duchenne muscular dystrophy
2023 · Alan J. Russell, Mike DuVall, et al. · Journal of Clinical Investigation · 42
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Plasma matrix metalloproteinase-9 response to eccentric exercise of the elbow flexors
2011 · Molly C. Madden, William C. Byrnes, et al. · European Journal of Applied Physiology · 22
A Phase 1, Double‐Blind, Placebo‐Controlled Trial of Sevasemten ( EDG ‐5506), a Selective Modulator of Fast Skeletal Muscle Contraction, in Healthy Volunteers and Adults With Becker Muscular Dystrophy
2025 · Joanne Donovan, Jeffrey A. Silverman, et al. · Muscle & Nerve · 11
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EDG-7500, A First-in-Class Cardiac Sarcomere Modulator, Demonstrates Favorable Tolerability, Safety, And Pharmacokinetics In Healthy Adults
2025 · Christopher Dufton, Marc Evanchik, et al. · Journal of Cardiac Failure · 5
Edg-002, a Novel Targeted Sarcomere Regulator Preserves Intrinsic Myosin-motor Function, Blunts Hypercontractility and Eliminates Lvot Obstruction in Cats With Hypertrophic Cardiomyopathy: in Vitro and in Vivo Evidence
2023 · Joanna Kaplan, Sarah Lehman, et al. · Journal of the American College of Cardiology · 2
Mechanistic diversity within RLC-dependent myosin ATPase inhibitors differentiates EDG-7500, a diastolic-selective cardiac sarcomere modulator
2026 · Craig A. Emter, Marcus Henze, et al. · JCI Insight · 1
Human Disposition, Metabolism, and Excretion of Sevasemten (EDG‐5506), a Selective Modulator of Fast Myosin in Healthy Volunteers
2026 · Molly Madden, Marc Evanchik, et al. · The Journal of Clinical Pharmacology · 1
Effects of sevasemten (EDG-5506) on safety, biomarkers, and functional measures in adults with Becker muscular dystrophy: results of a phase 1b, open-label study
2026 · Han Phan, Ben Barthel, et al. · EBioMedicine · 1
Direct and selective myosin-inhibition stabilizes the super-relaxed state of myosin and blunts post-tetanic potentiation in fast-skeletal muscle
2022 · Breanne Stamper, Sarah Lehman, et al. · Biophysical Journal · 1
Expression of Components of the Myostatin Signaling Pathway in Fasting Mouse Skeletal Muscle and Adipose
2008 · David L. Allen, Allison S. Cleary, et al. · Medicine & Science in Sports & Exercise · 1
Phase 1 Evaluation of the Pharmacokinetics of Sevasemten ( EDG ‐5506) for Potential Food Effect and Drug–Drug Interaction With a CYP3A4 Moderate Inhibitor
2026 · Molly Madden, Roxana Donisa Dreghici, et al. · Clinical and Translational Science
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Plasma Matrix Metalloproteinase-9 is Unchanged Following Downhill Running in Concentrically-trained Individuals
2011 · Molly C. Madden, David L. Allen, et al. · Medicine & Science in Sports & Exercise
Evaluation Of The Force-joint Angle Relationship As A Tool For Quantifying Force Generating Changes Following Eccentric Exercise
2010 · Molly C. Madden, David L. Allen, et al. · Medicine & Science in Sports & Exercise
Plasma Matrix Metalloproteinase-9 Activity As A Marker Of Exercise-induced Muscle Injury In Humans
2009 · Molly C. Madden, Nicole T. Bannister, et al. · Medicine & Science in Sports & Exercise
Metabolic And Adipogenic Regulation Of Myostatin And Activin Riib Expression In Adipose
2007 · David L. Allen, Sarah Lindsay, et al. · Medicine & Science in Sports & Exercise
Works count: 18
Citation count: 333
H-index: 5
I10-index: 5
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