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Author

Doris Rau

Institution: Amgen (Germany)
OpenAlex ID: A5019027771
T cell-engaging BiTE antibodies specific for EGFR potently eliminate KRAS- and BRAF-mutated colorectal cancer cells
2010 · Ralf Lutterbuese, Tobias Raum, et al. · Proceedings of the National Academy of Sciences · 166
Regression of Human Prostate Cancer Xenografts in Mice by AMG 212/BAY2010112, a Novel PSMA/CD3-Bispecific BiTE Antibody Cross-Reactive with Non-Human Primate Antigens
2012 · Matthias Friedrich, Tobias Raum, et al. · Molecular Cancer Therapeutics · 145
Side-by-side analysis of five clinically tested anti-EpCAM monoclonal antibodies
2010 · Markus Münz, Alexander Murr, et al. · Cancer Cell International · 124
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CD19-/CD3-bispecific antibody of the BiTE class is far superior to tandem diabody with respect to redirected tumor cell lysis
2006 · Michael Mølhøj, Sandrine Crommer, et al. · Molecular Immunology · 103
The PSMA-targeting Half-life Extended BiTE Therapy AMG 160 has Potent Antitumor Activity in Preclinical Models of Metastatic Castration-resistant Prostate Cancer
2021 · Petra Deegen, Oliver Thomas, et al. · Clinical Cancer Research · 102
Potent Control of Tumor Growth by CEA/CD3-bispecific Single-chain Antibody Constructs That Are Not Competitively Inhibited by Soluble CEA
2009 · Ralf Lutterbuese, Tobias Raum, et al. · Journal of Immunotherapy · 78
Antitumor Activity of an EpCAM/CD3-bispecific BiTE Antibody During Long-term Treatment of Mice in the Absence of T-cell Anergy and Sustained Cytokine Release
2009 · Maria Amann, Sandrine dÁrgouges, et al. · Journal of Immunotherapy · 64
Toward generalizable prediction of antibody thermostability using machine learning on sequence and structure features
2023 · Ameya Harmalkar, Roshan Rao, et al. · mAbs · 48
SINGLE-CHAIN FvANTIBODY-ALKALINE PHOSPHATASE FUSION PROTEINS PRODUCED BY ONE-STEP CLONING AS RAPID DETECTION TOOLS FOR ELISA
2002 · Doris Rau, Karl Kramer, et al. · Journal of Immunoassay and Immunochemistry · 30
Preclinical evaluation of AMG 160, a next-generation bispecific T cell engager (BiTE) targeting the prostate-specific membrane antigen PSMA for metastatic castration-resistant prostate cancer (mCRPC).
2019 · Julie Bailis, Petra Deegen, et al. · Journal of Clinical Oncology · 21
Cloning, functional expression and kinetic characterization of pesticide-selective F ab fragment variants derived by molecular evolution of variable antibody genes
2002 · Doris Rau, Karl Kramer, et al. · Analytical and Bioanalytical Chemistry · 14
Human IgG1 antibodies antagonizing activating receptor NKG2D on natural killer cells
2009 · Jutta Steigerwald, Tobias Raum, et al. · mAbs · 9
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Comparison of affinity ranking and immunochemical key data as measure for molecular antibody evolution
2003 · Karl Kramer, Doris Rau, et al. · Journal of Spectroscopy · 3
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Abstract 4561: Preclinical characterization of MT112/BAY 2010112, a novel PSMA/CD3-bispecific BiTE antibody for the treatment of prostate cancer
2011 · Ralf Lutterbuese, Matthias Friedrich, et al. · Cancer Research · 1
Abstract 2434: Novel primate-crossreactive BiTE antibodies that eliminate cancer cells expressing cMet, IGFR-1, FAP-alpha, PSCA, Endosialin, CAIX or Her2/neu
2010 · Tobias J. Raum, Doris Rau, et al. · Cancer Research · 1
Abstract 2435: Validation of Cynomolgus monkeys as relevant species for safety assessment of a novel human BiTE antibody platform for cancer therapy
2010 · Benno Rattel, Roman Kischel, et al. · Cancer Research
Abstract 2429: Evidence of a therapeutic window with a T cell-engaging BiTE antibody based on monoclonal antibody cetuximab
2010 · Ralf Lutterbuese, Oliver Thomas, et al. · Cancer Research
Abstract 5339: Inhibition of breast cancer cell proliferation and unique epitope recognition by EpCAM-specific human monoclonal antibody adecatumumab
2010 · Markus Münz, Alexander Murr, et al. · Cancer Research
Konstruktion von scFv-, Fab- und enzymkonjugierten Antikörperfragmenten für die Umweltanalytik
2002 · Doris Rau
Works count: 19
Citation count: 909
H-index: 11
I10-index: 11
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